Floxuridine - PubChem

Floxuridine - Compound Summary (CID 5790) Also known as: 2'-Deoxy-5-fluorouridine, FUDR, Fluorodeoxyuridine, 5-Fluorodeoxyuridine, Floxuridin, Deoxyfluorouridine, 50-91-9, Fluoruridine deoxyribose Molecular Formula: C₉H₁₁FN₂O₅ Molecular Weight: 246.192443 InChIKey: ODKNJVUHOIMIIZ-RRKCRQDMSA-N An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract. From: MeSH View the conformer with web-based 3D viewer View the conformer with Pc3D viewer application Download Pc3D viewer application 2D ASN.1 Text: Display 2D ASN.1 Text: Save 2D ASN.1 Binary: Save 3D ASN.1 Text: Display 3D ASN.1 Text: Save 3D ASN.1 Binary: Save 2D XML: Display 2D XML: Save 3D XML: Display 3D XML: Save 2D SDF: Display 2D SDF: Save 3D SDF: Display 3D SDF: Save BioActivity, this compound BioActivity, with similar compounds BioActivity, with similar conformers
Show subcontent titlesHide subcontent titlesTable of Contents Identification Depositor-Supplied Synonyms Compound Information Related Records Related Compounds with Annotation Related Compounds Related Substances Use and Manufacturing Medication Information Formulations/Preparations Pharmacology Pharmacological Action Therapeutic Uses Drug Warning Biomedical Effects and Toxicity Absorption, Distribution and Excretion Metabolism/Metabolites Mechanism of Action Interactions Antidote and Emergency Treatment Medical Surveillance Human Toxicity Excerpts Non-Human Toxicity Excerpts TSCA Test Submissions Toxicology References Safety and Handling Decomposition Protective Equipment and Clothing Other Preventative Measures Storage Conditions Cleanup Methods Disposal Methods Environmental Fate and Exposure Potential Probable Routes of Human Exposure Exposure Standards and Regulations FDA Requirements Monitoring and Analysis Methods Analytic Laboratory Methods Literature Depositor Provided PubMed Citations NLM Curated PubMed Citations Patents Depositor-Supplied Patent Identifiers Biomolecular Interactions and Pathways Protein Bound 3-D Structures Biosystems and Pathways Interactions Target Enzyme Action General Function Specific Function Gene Name GenBank Gene GenBank Protein References Biological Test Results BioAssay Results Classification Ontologies Substance Categorization Classification Chemical and Physical Properties Color/Form Odor Melting Point Dissociation Constants Octanol/Water Partition Coefficient Solubilities Spectral Properties Vapor Pressure Other Chemical/Physical Properties Computed Properties Expand all sub-sections	2D Structure 3D Conformer
Identification Help top of page Related Records Help top of page show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)show first sub-section only Use and Manufacturing Help top of page show all 2 sub-sections (Medication Information, Formulations/Preparations)show first sub-section only Pharmacology Help top of page show all 3 sub-sections (Pharmacological Action, Therapeutic Uses, Drug Warning)show first sub-section only Biomedical Effects and Toxicity Help top of page show all 10 sub-sections (Absorption, Distribution and Excretion, Metabolism/Metabolites, Mechanism of Action ...)show first sub-section only Safety and Handling Help top of page show all 6 sub-sections (Decomposition, Protective Equipment and Clothing, Other Preventative Measures, Storage Conditions ...)show first sub-section only Environmental Fate and Exposure Potential Help top of page Exposure Standards and Regulations Help top of page Monitoring and Analysis Methods Help top of page Literature Help top of page show all 2 sub-sections (Depositor Provided PubMed Citations, NLM Curated PubMed Citations)show first sub-section only Patents Help top of page Biomolecular Interactions and Pathways Help top of page show all 3 sub-sections (Protein Bound 3-D Structures, Biosystems and Pathways, Interactions)show first sub-section only Biological Test Results Help top of page Data Analysis Data Download BioActivity Summary: This Compound with Similar Compounds with Similar Conformers Classification Help top of page show all 2 sub-sections (Ontologies, Substance Categorization Classification)show first sub-section only Chemical and Physical Properties Help top of page show all 10 sub-sections (Color/Form, Odor, Melting Point, Dissociation Constants, Octanol/Water Partition Coefficient ...)show first sub-section only

_

_