5716457
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
8
8
8
8
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
3
-1
6
1
1
1
2
3
4
5
5
5
6
7
7
8
8
8
9
9
9
10
10
11
11
12
12
12
13
13
13
14
14
15
15
16
16
17
17
18
19
19
20
21
21
22
22
24
24
25
25
26
27
20
23
23
6
6
7
8
9
26
10
11
12
28
29
13
30
31
14
16
15
17
14
32
33
15
34
35
36
37
38
39
18
40
18
41
19
20
42
21
22
24
23
25
27
43
26
44
27
45
1
1
2
1
2
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
2
1
1
2
1
1
1
2
1
2
1
1
1
19
18
42
20
1
21
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
-0.9585
-2.405
-7.4348
-7.3076
5.3965
-6.7644
4.029
6.1482
6.1365
3.3193
3.308
5.334
5.3116
4.029
4.0054
1.949
1.9376
1.2623
-0.1583
-1.1722
-2.5837
-3.2074
-2.1933
-3.3279
-4.5839
-5.3466
-4.7228
6.4134
7.085
7.074
6.4003
5.9057
5.1182
5.0974
5.8747
4.2321
3.3885
3.3581
4.2051
1.425
1.4048
-0.3786
-2.8557
-5.027
-5.299
0.1046
0.2639
-0.1099
0.0821
0.0119
-0.0179
-0.0145
-1.2398
1.2589
-1.2368
1.1833
-2.3488
2.4398
-2.5495
2.521
-1.2543
1.146
-0.0678
-0.0961
-0.0182
-0.0439
0.0641
0.1572
-0.1469
0.0761
-0.0267
-0.1375
-1.513
-1.1139
1.2197
1.3895
-3.2832
-2.0831
2.3193
3.3723
-3.0066
-3.2354
3.2729
2.8401
-2.2072
2.0778
-0.1918
-0.2327
0.1636
-0.2185
-1.1875
-2.987
1.2502
-0.9329
-0.0965
0.1937
0.1894
-0.0999
0.0735
0.2341
0.4024
-0.7518
-0.4187
0.0092
0.3621
0.5354
0.7023
0.7683
1.079
0.1926
0.4734
-0.7503
-1.7939
1.6357
-0.8884
0.2755
1.5299
0.929
-0.6549
-0.4933
1.1304
-0.7656
-1.7949
-1.4888
-0.3027
0.9854
-0.5576
-0.1043
1.3924
0.5859
0.884
2.1402
2.6085
-1.8748
2.4487
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
005739E900000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
83.9716
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
50.987
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10 15 17168422774862320616
10299344 5 17989488524458560687
10411042 1 18123191196340104554
10670039 82 15357975595704770366
10673678 19 17751940240058842676
11497681 19 18196085763001913991
11796584 16 15195280967442662876
12236239 1 17704354363838031802
12403259 415 17821442452613075956
12516196 113 17748828527472434301
12616971 3 18060412513301993382
12730499 353 18113899355925971586
12788726 201 17060070224201606754
12916748 109 16370722621806773352
13533116 47 18272933812683270938
13782708 43 17894910689657179362
14170010 4 18411417315798703440
14251764 18 17346597478490802427
14294032 229 14780096447473392367
14933364 13 18407761426382421409
15131766 46 18127401482979799837
15183329 4 16845580832775926457
15419008 47 17676205762709102876
15537594 2 17846495950312226260
1577012 14 17561089098862526113
15961568 22 16443634609710783980
17844677 252 18337957796341660892
1813 80 17915750786622576046
20157964 124 18410858776591942328
20511986 3 17418082218460047400
20612939 158 18413111662837239648
20645477 70 18410011023210095850
21033648 29 17968362507615347892
21267235 1 18200599090940783854
21792961 116 17968668108457510218
22122407 14 18200610175919384833
221357 26 18335981991485190688
2297311 6 17095245796086980493
23081809 10 17775573026641516353
23522609 53 17631475469370176289
23557571 272 17095241389049673316
23559900 14 16588316002823889903
255183 451 17914065196896360286
2747138 104 17022913358813538001
3004659 81 16128657457386987730
335352 9 18411989062188174622
3383291 50 16371019546424297449
34797466 226 17313112951378694502
3633792 109 18410290277667440057
4073 2 18188215410855396122
46194498 28 17967535671140399660
5104073 3 16951108583008030377
5281201 14 18334011658306032756
54039377 194 17987523615850179758
5486654 2 15285361721533504473
59755656 215 17749390338647820290
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
522.21
18.56
1.91
1.49
15.52
0.01
0.75
-0.05
-0.09
-5.6
0.09
2.32
0.04
0.36
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1172.472
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
276.7
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2010.05.05
1
2
3
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.05.21
31
1 -0.23
10 -0.14
11 -0.14
14 0.14
15 0.14
16 -0.15
17 -0.15
18 0.03
19 -0.18
2 -0.57
20 0.05
21 0.03
22 0.09
23 0.63
24 -0.15
25 -0.15
26 0.13
27 -0.15
3 -0.52
4 -0.52
40 0.15
41 0.15
42 0.15
43 0.15
44 0.15
45 0.15
5 -0.84
6 0.91
7 0.1
8 0.37
9 0.37
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
3.4
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.05.21
10
1 2 acceptor
1 3 acceptor
1 3 anion
1 4 acceptor
1 5 cation
5 1 20 21 22 23 rings
6 21 22 24 25 26 27 rings
6 5 7 8 10 12 14 rings
6 5 7 9 11 13 15 rings
6 7 10 11 16 17 18 rings
27
0
0
0
1
1
0
0
1
1