5517
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
9
9
9
8
8
8
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
3
4
5
5
6
7
7
7
8
8
8
9
9
10
10
10
11
11
11
12
12
12
13
13
14
14
15
16
17
18
18
19
20
21
21
22
23
23
24
25
25
27
27
28
28
16
24
29
20
26
44
26
13
14
15
11
37
38
15
17
17
21
23
12
13
30
14
31
32
33
34
35
36
16
19
18
19
20
39
22
22
40
26
24
25
27
28
41
29
42
29
43
1
1
1
2
1
1
2
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
2
1
1
1
2
1
1
2
1
1
2
1
2
1
1
1
11
8
12
13
30
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
-2.2657
0.9566
-0.1227
2.7666
5.0835
5.5117
-3.1064
-6.0272
-0.8905
1.402
-5.1447
-5.4331
-3.6763
-4.1475
-1.7551
-1.371
0.4448
0.9048
-0.0127
2.3543
2.7547
3.2812
1.0087
0.7954
0.8361
4.7387
0.4143
0.4551
0.2442
-5.2363
-5.5818
-6.3162
-3.5698
-3.1928
-4.1937
-4.0478
-5.9681
-5.7133
0.3147
3.3943
0.9968
0.2499
0.3222
6.0559
3.7044
-1.9586
-5.838
3.386
2.3531
0.4147
1.1142
-1.051
0.3434
-0.4784
0.0053
1.3611
-0.2333
2.1407
1.3836
2.7086
0.6004
1.9282
2.983
2.233
-0.15
1.0801
-1.859
-2.5667
-2.5102
1.2155
-3.9081
-3.8514
-4.5503
0.0945
1.2616
1.8523
-0.6829
-0.8843
2.628
2.8836
-1.1336
-1.9464
4.0187
-1.0291
-1.9766
-4.4521
-4.3518
2.4796
0.0342
-2.2309
0.2537
0.1069
-0.58
0.5555
0.0058
0.0882
0.0555
0.1052
-0.3762
0.26
-0.0064
-0.0162
0.0392
0.0527
0.0981
0.0964
0.0788
0.0942
0.0777
0.0719
0.1414
-1.0471
1.3681
0.0595
-1.0091
1.4059
0.2173
-1.4663
1.3432
-0.1597
0.9882
-0.7436
-0.9966
0.7819
1.1025
-0.2845
0.0795
0.0654
2.3016
-1.9344
2.3605
-0.6088
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0000158D00000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
95.1499
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
66.395
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10074138 170 18052226760986968290
10090160 65 18409163303396632069
10906281 52 18261974980453374873
1100329 8 18266171927963118672
11135926 11 18337102368248713725
11421498 54 17560529417168045425
11488393 25 17844266046131832678
11719270 70 18410001118345539801
11991303 11 18042972162730695710
12156800 1 17613187433877194783
12553582 1 17187290063133497999
12788726 201 17398378115096241842
12839892 36 18265315236643280584
12969540 37 17903639583662953558
13140716 1 18339355361746874145
13257819 37 18263945335628829956
13692114 37 18127678546834693115
138480 1 17906170646666446099
14790565 3 18410577318052153133
14863182 85 18336558143782906437
14866123 147 18266451178405622714
15131766 46 15504362585742462324
15927050 60 18410009975212273410
16728300 4 17389914822358331650
16993438 75 18044098084571824043
17138139 8 17628329852755266199
18681886 176 18334852866084854464
19591789 44 18339077215232440193
20028762 73 18343579676661796607
20567600 347 18335707109029961362
21133410 32 16162501417539291931
21133410 62 18045475747167243719
21133410 90 16624638558843276475
21197605 99 18123758810016027683
21344244 181 18059874864975052806
21421861 104 18193561060654316001
21796203 349 17043774151913441515
22956985 138 17973999549323486850
23184049 29 17545598950905324283
23366157 5 17902239914140626628
23559900 14 17835231251769554441
283562 15 18342462512703369944
3178227 256 18337116756009464489
3383291 50 18410851024472145474
38695281 34 18411134744872057107
3882209 13 17470405619158458427
4280585 95 17547855148998259606
5486654 2 18338239370234676692
57359948 33 17604708851577904245
59755656 215 18335699386979853013
6669772 16 18342460310096900950
9709674 26 18122344571768817425
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
537.45
9.33
6.37
0.97
7.99
8.36
-0.18
-6.74
0.08
-2.55
0.35
-0.36
0.94
-0.16
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1191.754
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
287.6
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2010.05.05
1
8
9
5
4
7
6
2
3
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.05.21
36
1 -0.19
10 -0.3
11 0.27
13 0.37
14 0.37
15 0.41
16 0.19
17 0.41
18 0.09
19 -0.15
2 -0.19
20 0.47
21 -0.05
22 0.03
23 0.1
24 0.19
25 -0.15
26 0.71
27 -0.15
28 -0.15
29 0.19
3 -0.19
37 0.36
38 0.36
39 0.15
4 -0.57
40 0.15
41 0.15
42 0.15
43 0.15
44 0.5
5 -0.65
6 -0.57
7 -0.84
8 -0.99
9 -0.62
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
4
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.05.21
13
1 22 anion
1 4 acceptor
1 5 acceptor
1 6 acceptor
1 7 cation
1 8 cation
1 8 donor
3 5 6 26 anion
3 9 10 17 cation
5 7 11 12 13 14 rings
6 10 17 18 20 21 22 rings
6 23 24 25 27 28 29 rings
6 9 15 16 17 18 19 rings
29
1
0
1
0
0
0
0
1
1