54662715 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 8 8 8 8 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 4 5 5 5 6 6 6 7 7 7 8 8 8 9 9 9 10 10 10 11 11 12 12 13 14 14 14 14 15 15 16 18 18 19 19 19 20 20 21 21 22 22 22 23 24 24 24 25 25 25 26 26 26 27 27 28 28 29 15 56 16 17 23 8 10 16 12 13 23 17 22 47 9 12 30 11 15 31 11 13 32 17 33 34 35 21 18 19 20 36 37 38 18 39 40 20 41 42 43 44 28 45 24 25 46 29 27 50 51 26 48 49 27 52 53 54 55 29 57 58 1 1 2 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 8 5 12 9 30 2 1 9 8 11 15 31 1 1 10 5 11 13 32 1 1 11 9 17 10 33 2 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 1.3771 2.3251 -2.3672 1.0907 1.4879 0.63 -2.8409 1.588 0.2773 0.1076 -0.6452 1.5945 -0.057 4.8465 0.5235 2.4904 -2.0295 3.8488 5.6338 6.3084 -0.8481 -4.2252 0.5053 -4.6868 -5.1527 -5.3081 -5.0503 -1.0219 -0.4019 2.4894 -0.1146 -0.1225 -0.7344 1.418 2.5839 4.5659 1.001 -0.4181 4.1577 3.7694 5.4768 5.8591 6.99 6.6025 -1.3878 -4.3514 -2.4687 -4.776 -6.1314 -5.5858 -3.9357 -6.3001 -4.5704 -4.2237 -5.9258 1.5182 -1.6801 -0.5291 -2.1283 -0.9556 -0.1126 3.946 -0.6197 1.8756 -0.6887 -0.3492 -0.9457 -0.3481 -1.0834 1.1802 1.1633 -1.4869 -2.3089 -0.9021 -0.5665 -1.1651 -0.3748 -1.3376 1.8112 -0.2847 3.2664 0.1062 -1.4413 -2.2174 -1.2131 3.2344 3.9461 -0.7717 -0.2789 -0.7486 -2.1442 1.4884 1.5674 -2.3374 -3.0057 -2.7458 -0.2881 -2.0184 0.6384 -0.4533 -2.0613 -0.9716 1.2866 0.5453 -1.1406 -2.0747 -1.0506 0.731 0.6646 -2.6734 -3.0268 -1.5621 -1.0952 -3.0039 3.7158 5.0191 3.6605 -2.2207 1.9995 1.5749 -0.0972 0.5926 -0.2058 1.3309 1.9 -0.4586 0.6627 1.4689 -0.4031 -1.4599 2.5466 -1.001 0.9093 -0.4053 -2.0883 -1.1557 -1.2737 -0.2223 0.7324 -1.6212 0.1282 -1.1767 -2.3003 -1.1814 -0.2354 1.7811 2.6771 -1.452 0.3875 2.5063 1.1914 -2.07 1.8493 2.8949 0.1749 0.2779 -1.7395 -3.1449 -1.5859 -0.1797 -2.0543 0.4812 -1.0362 0.9376 0.4332 -1.5503 -2.1884 -1.2559 -1.2275 -2.9298 -2.9471 4.0589 -1.896 -0.1537 Conformer ID 11 2.1 PubChem ncbi.nlm.nih.gov 2011.09.13 0342163B00000001 Energy MMFF94 NoEstat 7 1.7.2 Szybki openeye.com 2012.11.26 78.6544 Feature Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 45.678 Fingerprint Shape 2 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 10764073 3 15584205653500991057 10930396 42 18266719421173066314 11135609 12 17843395435271620839 11135609 99 15768912693465711463 11421498 54 18040998388966449051 12293681 160 17894918420903630312 12633257 1 13542462120548898095 12788726 201 18263360283124778282 13009979 54 17417824962687640659 13149001 5 18044391640542094299 14713325 29 17700421273770974636 15775530 1 17249798879525597002 17357779 13 18411696573923676757 17492 89 18056191617355489151 1813 80 18201429289994693790 18336668 15 16988842791249211007 20775438 99 17689703582342912183 22182313 1 17986647343362689240 22393880 68 18188475991533623175 23352939 185 17988652904132270840 23559900 14 17703497905016548367 25147074 1 17607236559235907610 266924 1 17751637646221034746 283562 15 18189629258576014562 2838139 119 14418135140355140710 376196 1 17545580714843951321 4017518 198 17410211038541343276 4340502 62 7853576824467148789 469060 322 17845389781770166742 497634 4 16915963785549177854 5171179 24 18272083907196398120 57527295 17 17895182287110707971 5969126 39 18343023251190907564 Shape Multipoles 8 1.8.3 OEShape openeye.com 2012.11.26 558.39 10.41 3.69 2.64 0.81 5.29 1.29 -9.34 -9.65 -0.22 0.98 0.95 -1.5 0.4 Shape Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 1201.541 Shape Volume 7 1.8.3 OEShape openeye.com 2012.11.26 305 Conformer RMSD 7 2011.09.13 1 Diverse Conformer ID List 6 2012.02.08 1 23 10 13 11 24 25 5 20 2 15 7 18 21 4 19 12 16 14 22 6 8 9 17 3 Charge MMFF94 Partial 2 1.7.6 OEChem openeye.com 2012.02.08 34 1 -0.68 10 0.44 11 0.06 12 0.3 13 -0.03 14 -0.19 15 0.28 16 0.57 17 0.57 18 0.16 19 -0.2 2 -0.57 20 -0.2 21 -0.15 22 0.3 23 0.62 28 -0.15 29 -0.14 3 -0.57 36 0.1 4 -0.57 41 0.1 42 0.1 43 0.1 44 0.1 45 0.15 47 0.37 5 -0.66 56 0.4 57 0.15 58 0.15 6 -0.47 7 -0.73 8 0.3 Count Effective Rotor 7 1.7.6 OEChem ncbi.nlm.nih.gov 2012.01.18 9.4 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.1 OEShape openeye.com 2012.02.08 9 1 1 acceptor 1 1 donor 1 2 acceptor 1 3 acceptor 1 4 acceptor 1 7 donor 5 22 24 25 26 27 rings 6 6 13 21 23 28 29 rings 8 5 6 8 9 10 11 12 13 rings 29 4 4 0 0 0 0 0 1 2