Bookmark and Share

Compound Summary for: CID 54454

Simvastatin

Also known as: Zocor; Synvinolin; MK-733; Simvastatine; Colemin; Sinvacor; Sivastin; Lipex; Medipo
Molecular Formula: C25H38O5   Molecular Weight: 418.56622   InChIKey: RYMZZMVNJRMUDD-HGQWONQESA-N
A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.   From: MeSH
Show subcontent titlesTable of Contents
Identification
Related Records
show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)
Use and Manufacturing
Pharmacology
Biomedical Effects and Toxicity
Safety and Handling
Environmental Fate and Exposure Potential
Exposure Standards and Regulations
Literature
Patents
Biomolecular Interactions and Pathways
Biological Test Results
Classification
Chemical and Physical Properties
_ _