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Compound Summary for: CID 54454


Also known as: Zocor; Synvinolin; MK-733; Simvastatine; Colemin; Sinvacor; Sivastin; Lipex; Medipo
Molecular Formula: C25H38O5   Molecular Weight: 418.56622   InChIKey: RYMZZMVNJRMUDD-HGQWONQESA-N
A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.   From: MeSH
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