5411
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
8
8
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
3
3
3
4
4
4
5
5
5
5
6
6
7
7
7
8
8
9
9
9
10
10
11
11
11
12
12
12
13
13
14
14
15
16
18
18
18
19
19
19
10
17
17
6
8
26
9
18
19
6
7
20
21
22
23
11
24
25
13
14
10
27
28
29
30
31
32
33
15
16
17
15
34
16
35
36
37
38
39
40
41
42
43
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
2
1
1
1
1
2
1
1
1
1
1
1
1
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
2.6684
2.0965
-3.5615
6.3012
-6.0051
-4.7143
-7.2574
-2.2537
4.8792
4.057
-8.5234
0.4012
-1.1737
-1.9718
0.1423
-0.6558
1.7733
7.0927
6.7051
-6.0037
-6.0382
-4.7033
-4.7007
-7.2937
-7.2168
-3.7056
4.5815
4.6246
4.2535
4.2557
-8.5308
-9.4059
-8.609
-1.3583
-2.7639
0.9332
-0.4756
6.8155
6.9578
8.1588
6.3354
7.7973
6.3819
-0.0653
-2.2942
0.7635
0.5659
0.7101
-0.1045
-0.1691
0.3064
0.8682
-0.4103
0.6711
-0.6208
1.2084
-1.0713
0.7488
-1.5309
-1.1
1.7984
-0.2744
1.3862
1.3483
-0.7446
-0.7496
-0.8098
-0.828
1.7663
1.4838
1.455
-0.9801
-1.0413
1.2974
0.0244
1.3231
2.2797
-1.8153
1.4936
-2.602
2.4183
2.3918
1.5705
-1.2994
-0.372
0.1358
0.1074
0.168
-0.0856
0.1994
-0.083
-0.0863
-0.0366
-0.0369
0.134
0.1558
0.0321
0.0649
-0.0376
0.016
0.0128
0.0666
0.1189
0.2207
-0.9307
0.7818
-0.9754
0.8042
-0.973
-0.9251
0.8385
-0.1329
0.993
-0.7591
1.0719
-0.7158
0.9298
0.0618
-0.843
-0.0776
0.0175
0.0099
0.1066
1.0807
-0.6909
0.3311
-0.83
-0.9612
-1.8945
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0000152300000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
48.5585
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
30.446
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10 15 17822009830730702400
10354089 29 17458344148404962284
106641 1 17821731658858012625
10968037 39 18411980261546678655
11315181 36 18272934921940107929
11638347 137 16371000785485168264
13073987 5 16950835896056178601
13288520 33 9511466627884586410
13533116 47 18272366417734610410
13885169 127 9367356929209782683
14123256 10 18412544305957371493
14251752 14 13183026198159768203
14251764 18 18259701203629015883
14251764 46 18411418410102708104
15048467 5 18411135844225494265
15690457 1 11314310563972141905
17834076 25 18342175565853037741
20281389 69 18186515497654982876
21095086 128 16702301248347281351
21150785 3 17060621105407701821
21267235 1 18339080368018361122
221357 26 17704073984885493080
22224240 67 17967812764512067627
23035841 295 15052012364512514181
23402539 116 18342452690850830150
23521765 1 18342175566333111605
23559900 14 18201430445436108520
246663 6 12247679387937426533
28498 318 9871754585389764857
33532 11 9655582902445314996
335352 9 18410575114775563508
33684 2 18410855451538240201
34797466 226 17846503625714404396
3545911 37 18408886230808651534
4325135 7 18410293605813491925
4340502 62 16732983111314042595
4463277 17 18412262822775744109
5486654 2 18412826893156583971
5758199 1 18410857651199851531
59682541 35 18113903792853879393
8209 1 18413671309496735861
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
369.31
21.83
1.54
0.66
10.75
0.34
-0.05
-8.94
-1.24
-1.41
0.1
-0.32
0.01
0.29
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
732.995
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
221
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.02.08
1
119
112
158
193
124
132
206
170
122
101
82
217
35
86
85
167
189
185
123
224
140
169
210
83
207
74
209
165
142
143
73
229
69
17
150
18
216
164
199
107
37
186
192
121
92
191
71
41
28
146
130
213
24
114
32
190
220
171
162
211
187
103
221
155
67
12
152
62
178
84
182
181
113
135
219
177
110
57
139
173
6
208
48
166
163
96
89
43
126
93
144
226
22
38
81
50
161
108
40
55
39
34
156
102
70
205
174
109
120
100
63
131
223
197
184
148
77
198
203
15
88
25
98
56
136
172
79
99
129
31
153
145
115
201
13
222
16
128
47
195
116
5
76
159
196
44
53
176
157
218
30
54
94
228
175
4
14
97
45
95
133
80
160
180
212
225
134
72
20
141
183
33
64
19
21
61
46
23
111
58
10
51
3
104
68
202
230
27
66
36
52
87
149
179
200
204
9
154
137
168
188
227
194
151
75
7
65
118
11
8
138
147
29
60
106
26
105
125
42
78
127
117
215
59
2
90
49
214
91
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.05.21
21
1 -0.43
10 0.28
12 0.09
13 -0.15
14 -0.15
15 -0.15
16 -0.15
17 0.63
18 0.27
19 0.27
2 -0.57
26 0.4
3 -0.87
34 0.15
35 0.15
36 0.15
37 0.15
4 -0.81
6 0.37
8 0.1
9 0.27
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
9
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.05.21
6
1 11 hydrophobe
1 2 acceptor
1 3 cation
1 3 donor
1 4 cation
6 8 12 13 14 15 16 rings
19
0
0
0
0
0
0
0
1
2