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Compound Summary for: CID 53846677

SureCN7802295

Also known as: CTK5E0054, 745-65-3
Molecular Formula: C20H34O5   Molecular Weight: 354.48096   InChIKey: GMVPRGQOIOIIMI-VZDIDWBNSA-N
Alprostadil is produced endogenously and causes vasodilation by means of a direct effect on vascular and ductus arteriosus (DA) smooth muscle, preventing or reversing the functional closure of the DA that occurs shortly after birth. This results in increased pulmonary or systemic blood flow in infants. In infants, it is used for palliative, not definitive, therapy to temporarily maintain the patency of the ductus arteriosus until corrective or palliative surgery can be performed in neonates who have congenital heart defects and who depend upon the patent ductus for survival. In adults, it is used for the treatment of erectile dysfunction due to neurogenic, vasculogenic, psychogenic, or mixed etiology.   From: DrugBank
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