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Compound Summary for: CID 5381226

Rifampin

Also known as: Rifampicin, Rifadin, Rimactane, Rimactan, Tubocin, Rifamycin AMP, Rifampicinum, Rifoldin, Riforal
Molecular Formula: C43H58N4O12   Molecular Weight: 822.94022   InChIKey: FZYOVNIOYYPUPY-ZTWDQPHTSA-N
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)   From: MeSH
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