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Compound Summary for: CID 5362449

Dextromethorphan

Also known as: Methorphan, Levomethorphan, 3-Methoxy-17-methylmorphinan, l-Methorphan, CHEBI:4470, DEA No. 9210, (-)-3-Methoxy-N-methylmorphinan
Molecular Formula: C18H25NO   Molecular Weight: 271.3972   InChIKey: MKXZASYAUGDDCJ-CGTJXYLNSA-N
Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.   From: MeSH
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