Dextromethorphan - PubChem

Dextromethorphan - Compound Summary (CID 5362449) Also known as: Levomethorphan, Methorphan, 3-Methoxy-17-methylmorphinan, CHEBI:4470, DEA No. 9210, EINECS 204-751-7, Morphinan, 3-methoxy-17-methyl-, l- Molecular Formula: C₁₈H₂₅NO Molecular Weight: 271.3972 InChIKey: MKXZASYAUGDDCJ-CGTJXYLNSA-N Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity. From: MeSH View the conformer with web-based 3D viewer View the conformer with Pc3D viewer application Download Pc3D viewer application 2D ASN.1 Text: Display 2D ASN.1 Text: Save 2D ASN.1 Binary: Save 3D ASN.1 Text: Display 3D ASN.1 Text: Save 3D ASN.1 Binary: Save 2D XML: Display 2D XML: Save 3D XML: Display 3D XML: Save 2D SDF: Display 2D SDF: Save 3D SDF: Display 3D SDF: Save BioActivity, this compound BioActivity, with similar compounds BioActivity, with similar conformers
Show subcontent titlesHide subcontent titlesTable of Contents Identification Depositor-Supplied Synonyms Compound Information Related Records Related Compounds with Annotation Related Compounds Related Substances Use and Manufacturing Medication Information Methods of Manufacturing Formulations/Preparations Pharmacology Pharmacological Action Therapeutic Uses Drug Tolerance Minimum/Potential Fatal Human Dose Biomedical Effects and Toxicity Absorption, Distribution and Excretion Metabolism/Metabolites Mechanism of Action Interactions Toxicity Summary Human Toxicity Excerpts Toxicology References Safety and Handling Stability/Shelf Life Monitoring and Analysis Methods Analytic Laboratory Methods Clinical Laboratory Methods Literature Depositor Provided PubMed Citations NLM Curated PubMed Citations Patents Depositor-Supplied Patent Identifiers Biomolecular Interactions and Pathways Biosystems and Pathways Biological Test Results BioAssay Results Classification Ontologies Substance Categorization Classification Chemical and Physical Properties Spectral Properties Other Chemical/Physical Properties Computed Properties Expand all sub-sections	2D Structure 3D Conformer
Identification Help top of page Related Records Help top of page show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)show first sub-section only Use and Manufacturing Help top of page show all 3 sub-sections (Medication Information, Methods of Manufacturing, Formulations/Preparations)show first sub-section only Pharmacology Help top of page show all 4 sub-sections (Pharmacological Action, Therapeutic Uses, Drug Tolerance, Minimum/Potential Fatal Human Dose)show first sub-section only Biomedical Effects and Toxicity Help top of page show all 7 sub-sections (Absorption, Distribution and Excretion, Metabolism/Metabolites, Mechanism of Action ...)show first sub-section only Safety and Handling Help top of page Monitoring and Analysis Methods Help top of page show all 2 sub-sections (Analytic Laboratory Methods, Clinical Laboratory Methods)show first sub-section only Literature Help top of page show all 2 sub-sections (Depositor Provided PubMed Citations, NLM Curated PubMed Citations)show first sub-section only Patents Help top of page Biomolecular Interactions and Pathways Help top of page Biological Test Results Help top of page Data Analysis Data Download BioActivity Summary: This Compound with Similar Compounds with Similar Conformers Classification Help top of page show all 2 sub-sections (Ontologies, Substance Categorization Classification)show first sub-section only Chemical and Physical Properties Help top of page show all 3 sub-sections (Spectral Properties, Other Chemical/Physical Properties, Computed Properties)show first sub-section only

_

_