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Compound Summary for: CID 5353272

12-Hydroxy-5,8,10,14-eicosatetraenoic Acid

Also known as: 12-hydroxyicosa-5,8,10,14-tetraenoic acid; 12-R-Hete; 12-S-Hete; 12(S)-hydroxy-eicosatetraenoic acid; 12-S-Hydroxyeicosatetraenoic acid
Molecular Formula: C20H32O3   Molecular Weight: 320.46628   InChIKey: ZNHVWPKMFKADKW-GIZKKEBHSA-N
A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)   From: MeSH
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