53468168
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
16
16
16
16
16
16
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
4
5
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
20
21
22
23
24
25
26
27
28
29
30
31
31
32
32
33
34
35
36
36
37
37
38
39
40
41
42
43
43
44
45
46
46
47
47
47
48
48
48
49
49
49
50
50
50
51
51
51
52
52
52
53
53
53
54
54
54
55
55
55
56
56
56
57
57
57
58
58
58
59
59
59
60
60
60
61
61
61
62
62
62
63
63
63
64
64
64
65
65
65
66
66
66
67
67
67
68
68
68
69
69
69
70
70
70
71
71
71
72
72
72
73
73
73
74
74
74
75
75
75
76
76
76
77
77
77
78
78
78
79
79
79
80
80
80
81
81
82
82
82
83
83
83
84
84
84
85
85
85
86
86
86
87
87
88
88
88
89
89
89
91
91
91
92
92
92
93
93
94
94
94
96
96
96
98
98
98
99
99
99
101
101
101
102
102
102
103
103
103
104
104
104
105
106
106
106
107
107
108
108
108
109
109
110
110
110
112
113
113
113
114
114
114
115
115
116
116
116
118
118
119
120
120
121
122
122
122
124
124
124
125
125
125
126
126
127
127
127
128
128
128
129
129
129
130
130
130
131
132
132
132
133
133
133
134
134
135
136
137
137
138
138
139
139
141
141
142
142
142
143
143
143
145
145
146
146
147
147
148
148
148
149
149
151
152
152
152
154
154
154
155
155
155
156
156
156
159
159
159
160
160
160
162
162
162
165
165
165
167
167
167
168
168
168
169
169
169
170
170
171
171
173
174
174
174
175
175
175
176
176
176
177
177
178
178
179
180
180
181
181
182
182
182
183
183
185
185
185
187
187
187
188
188
189
189
189
190
190
191
191
192
192
192
193
193
193
197
197
197
198
198
198
199
199
199
200
200
201
201
202
202
202
203
204
204
205
205
205
208
208
208
210
210
211
211
211
212
212
212
213
213
214
214
214
215
215
3
109
4
115
133
142
6
149
182
90
95
97
100
105
111
112
117
119
121
123
131
135
141
329
140
144
150
153
157
158
161
163
164
166
170
373
171
375
172
173
179
184
396
188
399
184
186
194
195
196
206
414
203
209
213
420
84
86
90
88
92
97
89
105
236
95
103
240
96
112
244
100
108
251
107
119
262
111
114
263
117
128
276
118
131
277
120
135
278
123
132
282
134
153
304
140
148
307
138
157
312
139
161
314
136
315
316
144
162
318
150
154
320
152
166
328
147
173
330
159
163
332
156
179
341
164
176
344
158
352
353
172
185
357
183
186
369
177
207
374
181
195
376
180
203
379
189
194
380
196
199
391
204
209
400
207
412
413
207
415
210
416
417
215
421
422
85
95
216
87
217
218
87
219
220
221
222
91
100
223
90
94
224
93
225
226
93
227
228
229
230
99
101
231
97
98
232
102
104
233
106
234
235
237
238
239
110
241
242
109
111
243
245
246
247
107
248
249
250
113
252
115
117
253
254
255
256
257
258
118
121
259
260
116
123
261
264
265
122
125
266
267
268
120
124
269
126
127
270
271
129
130
272
273
274
275
136
137
279
280
281
140
283
284
285
289
290
286
287
288
134
141
144
291
138
292
293
143
294
139
145
146
295
150
296
149
297
298
299
147
300
301
158
302
303
151
305
151
306
164
308
155
163
309
310
311
313
153
160
317
166
167
319
169
321
322
157
165
323
161
170
324
168
325
326
171
172
327
174
175
331
178
333
334
177
335
336
184
337
338
339
340
342
343
181
345
346
347
348
349
350
186
188
351
354
355
190
191
180
187
356
358
359
183
360
361
196
362
194
197
363
193
364
365
366
367
192
195
368
200
370
201
371
198
205
372
202
377
378
381
382
383
211
384
385
208
209
386
206
387
206
388
210
389
390
204
213
392
393
394
395
212
397
398
401
402
403
404
405
214
406
407
408
409
215
410
411
418
419
1
1
1
1
1
1
1
1
1
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
2
2
2
2
2
2
2
2
2
2
1
1
1
1
2
2
2
1
1
1
1
2
2
2
2
2
1
1
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
84
47
85
95
216
1
1
88
48
91
100
223
1
1
89
49
94
90
224
2
1
94
89
101
99
231
2
1
96
51
98
97
232
2
1
98
96
104
102
233
2
1
103
50
109
111
243
1
1
107
53
113
105
252
2
1
108
52
115
117
253
1
1
114
54
116
123
261
1
1
116
114
125
122
266
2
1
120
57
124
119
269
2
1
132
58
141
144
291
1
1
134
59
143
131
294
2
1
138
61
133
150
296
1
1
139
62
149
135
297
2
1
147
67
142
164
308
1
1
148
60
155
163
309
1
1
152
66
160
153
317
2
1
154
65
167
166
319
2
1
156
69
165
157
323
2
1
159
68
170
161
324
2
1
162
64
171
172
327
1
1
176
70
188
186
351
2
1
180
76
187
179
356
2
1
183
73
182
196
362
1
1
185
72
197
194
363
2
1
189
77
192
195
368
1
1
192
189
205
198
372
2
1
199
78
208
209
386
1
1
204
79
213
203
392
2
1
1
5
255
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
17.7723
18.9462
17.0489
20.6663
27.3151
28.2942
22.9184
21.2111
7.8538
11.7422
24.3288
18.0235
4.8533
15.4455
25.427
25.0983
17.8718
3.9529
26.2008
17.2499
17.7704
18.0504
13.5278
5.298
19.0828
3.5003
23.2157
19.9236
25.9844
8.6713
22.4503
17.61
18.5572
21.9737
24.4387
16.7016
29.5032
17.0935
29.7703
19.3866
20.4721
31.6303
9.1865
28.7302
31.2638
30.1454
21.5227
9.864
22.9851
19.7787
6.5156
13.7928
24.1499
18.9341
16.9004
4.9987
25.0044
18.8939
5.5584
19.2242
17.2544
24.4602
26.3706
19.1727
12.2248
8.1042
23.365
21.7534
22.3804
26.7395
2.5082
19.7674
29.7077
4.7473
21.8751
26.7745
20.6715
30.7601
29.7267
3.5939
3.0516
27.4573
35.0046
20.9718
21.6225
22.4582
22.5184
10.673
22.53
22.0423
11.482
10.173
11.173
23.5087
20.3902
7.4496
8.5725
6.518
23.8206
12.1814
24.1757
6.3671
19.138
5.7373
23.4072
24.7994
23.7956
15.4779
18.469
5.4356
19.0184
5.7877
24.7904
18.8852
17.2062
17.9118
16.1759
5.279
24.4698
24.7547
25.1999
17.2267
18.8718
25.6222
16.9385
26.1947
16.2533
17.6505
26.4868
26.4898
4.952
18.9515
16.2996
5.1397
25.2186
26.7801
26.6042
15.5254
25.3969
18.4255
18.0074
22.3352
4.2338
19.0445
27.7749
27.599
23.9226
20.0457
26.3489
13.8386
28.1844
7.0542
6.2005
10.7132
19.3153
20.7133
18.9942
3.4141
22.6373
6.1045
23.54
19.3361
20.8892
25.3996
21.1799
9.3313
9.7823
5.9008
18.3586
22.1235
18.4316
19.5344
22.8375
20.6472
22.1791
27.9179
4.9511
9.6334
23.9651
25.4387
22.3407
29.2851
30.2867
17.3846
20.0348
28.9133
26.2159
28.5092
21.04
8.7025
10.4153
20.048
26.0594
20.3363
21.4414
30.6396
19.0351
19.4428
30.6461
8.5536
10.2663
26.8366
27.948
28.9381
19.252
9.3355
3.7976
31.5691
30.2995
26.6801
18.4508
32.3638
29.9003
33.2869
34.0815
20.2575
21.925
21.1185
22.5582
23.0774
23.129
22.6932
10.673
23.1634
11.792
12.0484
10.2378
9.5666
11.7795
11.1082
24.1156
6.9184
6.6116
23.8008
23.2069
23.5478
23.7137
24.5891
24.6376
20.275
6.4888
6.9869
19.9529
5.9713
6.1248
5.2533
5.3499
24.9265
25.4062
24.6723
13.5979
24.0495
15.3217
19.0786
17.9998
5.2101
4.858
5.661
24.7453
25.3916
18.0713
24.7368
18.3155
16.8582
17.2372
18.0539
4.6899
5.8828
25.3747
17.7452
16.982
25.3138
16.7964
16.335
17.0805
16.4626
4.3815
25.609
16.1113
15.6498
16.3954
18.2744
17.5154
18.0728
26.1752
26.7982
27.0276
26.1814
27.0228
26.7984
18.3424
16.8941
15.8754
4.522
26.2412
14.8954
25.542
17.5272
18.3103
22.2173
22.1198
4.59
3.7959
4.968
28.1378
27.8529
18.8347
24.3886
19.4264
26.4289
26.5904
17.2257
28.8012
24.1795
26.7336
25.7538
6.6413
18.5591
10.5158
11.9546
19.811
19.0346
20.6896
22.0347
5.4848
6.0156
18.7182
7.6361
16.6645
22.8407
21.4691
22.0356
9.1625
9.6594
6.5205
5.9897
18.0202
18.3378
21.6001
21.6794
22.5979
17.9951
18.7894
27.1664
21.1719
20.3169
20.1225
22.2028
22.7987
22.1555
28.4854
2
2.4548
4.3313
4.8621
25.6609
19.1665
21.7211
22.8869
29.429
29.4656
31.1041
19.6467
26.5165
26.8021
27.9531
28.6826
20.3634
30.2772
8.2178
10.9924
20.2827
22.0442
5.2098
17.0492
21.5306
25.7589
25.4732
27.203
20.0898
19.0216
18.4152
19.0485
19.994
19.259
31.261
7.9765
10.7511
27.1372
27.4228
31.3801
29.3703
18.8767
18.7585
19.6273
16.0976
32.0254
31.2349
29.8698
30.2971
26.3796
26.0939
18.3726
17.8357
18.529
31.9076
32.698
29.9631
30.5186
33.7431
32.9526
3.005
4.0564
8.6094
2.4628
27.3603
28.0361
33.6253
34.4158
30.7419
35.4973
35.0842
9.5128
-13.8654
10.2664
-13.6012
-5.4279
-5.073
4.0808
6.8313
-10.6737
-13.4989
1.167
7.0226
-5.956
-12.236
-1.8784
1.818
3.8718
-0.4379
-5.0218
2.1672
-9.997
0.7225
12.218
4.9889
12.8521
0.106
-6.2359
-8.5731
-12.286
9.4477
-5.8984
-1.0377
-2.3909
-11.1786
11.2477
-9.5564
-9.7815
-7.8693
-8.1717
-5.4342
-8.2096
-2.8991
14.0749
7.664
2.6799
6.8517
4.5049
-11.1448
1.7346
7.1071
-7.1806
-13.2576
-1.1734
5.9088
-12.1709
-2.2181
-4.1872
2.8594
2.9407
-10.0843
11.893
-6.6942
-0.7984
-0.1775
10.6164
7.4624
-11.5444
-8.2521
11.086
-10.3643
1.5258
-3.1687
-6.108
8.6588
-8.8834
8.3259
-6.0813
-1.0267
4.0584
9.9509
8.306
13.3046
0.6496
5.3924
6.1141
4.7678
5.7376
-11.7326
2.6748
3.5986
-11.1448
-10.1937
-10.1937
2.8798
6.2602
-8.649
-9.9784
-9.0126
3.83
-12.6005
2.1347
-10.0011
7.9322
-8.3876
0.779
4.035
-0.1907
-13.692
8.7344
-10.3647
6.9223
-5.5999
-0.0892
4.893
-13.8959
4.6639
-12.919
-3.9356
-2.1679
-3.1729
0.8232
5.3923
3.8761
-2.6755
4.4347
0.9247
5.1632
-11.4484
-3.178
-2.1781
-0.4785
1.844
10.9943
1.2516
-5.2097
0.114
1.837
11.6956
-6.239
-10.7526
1.5144
-13.1081
1.6751
0.8313
0.2155
1.9386
-12.3949
-9.4442
-5.8167
11.2675
1.1278
6.0746
4.5582
9.7541
-8.7612
11.5854
11.856
1.1023
-7.7014
6.3877
-7.1819
-1.1813
-8.8332
-11.4748
12.4699
8.6964
10.1195
7.3667
-9.0523
-6.8435
-1.6078
-2.1788
-10.6749
13.3162
12.5081
-9.0838
7.6798
11.1084
10.367
9.4413
-9.7876
-4.7525
-4.4669
-8.826
-4.1499
-7.6563
10.0706
-9.8902
-7.0292
11.4738
11.7318
-7.1553
11.0583
-5.1212
-7.9636
-2.7628
-4.1716
-6.3592
0.7098
12.4627
12.7206
11.6876
7.0409
5.6097
-7.7605
13.0861
8.9719
1.0944
2.4152
12.6753
-6.4853
0.4874
5.8822
0.872
0.265
4.9316
6.6553
6.4752
4.1559
4.7988
5.6304
6.3325
-12.5826
3.2417
-11.6817
-10.8926
-9.5771
-10.0648
-10.0648
-9.5771
3.0069
-9.3125
-8.3997
4.4496
3.9181
1.9949
1.7212
1.6727
2.5482
7.4788
-10.609
-9.9868
8.1741
-7.4773
-7.9036
-8.0001
-8.8716
3.4281
4.162
4.6418
-13.8462
0.3749
-14.5276
8.8474
8.3291
-9.7871
-10.5901
-10.9423
-0.7075
-0.241
5.138
-0.9733
5.9494
-14.409
-13.2767
4.0604
-3.7424
-3.7948
-3.1747
5.7322
5.962
-2.1376
5.0382
4.2926
3.8312
-11.7319
-2.2765
-4.0496
5.7667
5.0212
4.5597
2.8351
-10.8434
-11.9025
-3.7141
-2.7159
-1.8697
-1.6402
-3.4896
-2.642
1.9597
11.1704
10.5421
1.1982
2.3397
12.2663
-7.0765
1.1222
0.9734
-13.7168
-12.5267
2.1826
2.1139
3.1301
-0.2872
2.5043
-9.6019
-13.1058
-9.4163
-5.2018
-6.3877
12.5123
1.1908
-6.1414
-1.301
-0.8613
6.5371
-0.2665
10.3418
11.1744
-8.3888
-8.2084
12.205
-7.5558
6.3687
5.7741
-1.1299
7.869
1.9629
-11.8752
13.0183
-7.7
10.1351
9.5118
7.3857
7.9803
-9.5718
-8.4326
-6.5112
-7.2762
11.6666
-2.0481
-2.1142
-10.814
13.6465
13.8409
12.9859
11.8885
12.5318
13.1276
-9.3335
1.1707
2.1435
7.6608
7.0662
10.0201
-3.3213
-9.765
-9.4942
-4.1494
-5.3457
-4.2337
-4.6334
9.5284
10.2725
-10.1644
-10.4855
-7.5436
-6.3532
11.0873
11.5052
-7.7291
-5.43
9.0717
-1.3022
-9.3989
11.6006
10.8565
8.7739
-6.2958
-3.5518
-4.1851
-4.7915
-6.0754
-5.7671
0.6302
12.6892
13.1072
11.1454
11.8895
-1.0279
6.0543
-7.267
-8.1358
-8.2541
-9.4161
1.5143
1.6166
-10.2815
4.3015
13.2176
12.4735
-5.8703
-6.5635
-7.1004
0.0675
-0.0348
5.2654
5.8369
1.2919
1.3942
10.145
10.3638
14.3015
8.5001
13.917
13.0825
-0.1549
-0.2572
7.0206
0.2732
1.2645
5
6
5
6
5
6
5
6
5
5
5
6
8
8
6
6
8
8
6
5
8
8
5
5
6
6
6
5
6
6
8
8
6
6
6
5
8
8
5
6
8
8
6
84
88
89
94
96
98
103
107
108
114
116
120
126
126
132
134
136
137
138
139
145
146
147
148
152
154
156
159
162
176
178
178
180
183
185
189
190
191
192
199
200
201
204
216
223
224
101
232
104
243
113
253
261
125
124
136
137
141
143
145
146
296
297
151
151
308
155
160
167
165
170
171
188
190
191
187
362
197
368
200
201
205
208
206
206
213
0
Compound
Canonicalized
5
2011.09.13
0
Compound Complexity
7
E_COMPLEXITY
3.396
Cactvs
xemistry.com
2012.02.08
7160
Count
Hydrogen Bond Acceptor
5
E_NHACCEPTORS
3.396
Cactvs
xemistry.com
2012.02.08
50
Count
Hydrogen Bond Donor
5
E_NHDONORS
3.396
Cactvs
xemistry.com
2012.02.08
42
Count
Rotatable Bond
5
E_NROTBONDS
3.396
Cactvs
xemistry.com
2012.02.08
38
Fingerprint
SubStructure Keys
16
extended 2
E_SCREEN
3.396
Cactvs
xemistry.com
2012.02.08
00000371F07FFE00700000000000000000000000000162C00000306000000000000000014000001E04100800000D2CE5D806B3CE83C00200A802A5D27800820000A422000988818E6CC88A763E82DDB394718066F61398D9C7BDDFA28E20000000000200004000000000040000000000000000
InChI
Standard
1
1.0.4
InChI
iupac.org
2012.02.08
InChI=1S/C132H207N37O40S6/c1-14-64(9)101-126(204)142-49-96(179)145-86-57-211-210-56-85-107(185)141-48-95(178)144-76(38-39-98(181)182)110(188)153-82(53-172)117(195)158-89-60-214-212-58-87(157-118(196)83(54-173)155-119(86)197)120(198)148-73(29-20-22-40-133)109(187)152-81(52-171)115(193)147-74(30-21-23-41-134)111(189)163-100(63(7)8)128(206)161-88(121(199)149-77(45-69-34-36-70(175)37-35-69)112(190)146-75(31-24-42-139-132(137)138)108(186)150-79(47-94(136)177)106(184)140-50-97(180)162-103(66(11)16-3)130(208)168-43-25-32-91(168)124(202)159-85)59-213-215-61-90(123(201)166-102(65(10)15-2)129(207)156-84(55-174)116(194)154-80(51-170)114(192)143-68(13)105(183)165-101)160-125(203)92-33-26-44-169(92)131(209)104(67(12)17-4)167-113(191)78(46-93(176)71-27-18-19-28-72(71)135)151-127(205)99(62(5)6)164-122(89)200/h18-19,27-28,34-37,62-68,73-92,99-104,170-175H,14-17,20-26,29-33,38-61,133-135H2,1-13H3,(H2,136,177)(H,140,184)(H,141,185)(H,142,204)(H,143,192)(H,144,178)(H,145,179)(H,146,190)(H,147,193)(H,148,198)(H,149,199)(H,150,186)(H,151,205)(H,152,187)(H,153,188)(H,154,194)(H,155,197)(H,156,207)(H,157,196)(H,158,195)(H,159,202)(H,160,203)(H,161,206)(H,162,180)(H,163,189)(H,164,200)(H,165,183)(H,166,201)(H,167,191)(H,181,182)(H4,137,138,139)/t64-,65-,66-,67-,68-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,99-,100-,101-,102-,103-,104-/m0/s1
InChIKey
Standard
1
1.0.4
InChI
iupac.org
2012.02.08
LXXJDERKESNVHX-OYUHEIPXSA-N
Log P
XLogP3-AA
7
3.0
sioc-ccbg.ac.cn
2012.02.08
-7.9
Mass
Exact
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.02.08
3143.365885
Molecular Formula
1
2.1
PubChem
ncbi.nlm.nih.gov
2012.02.08
C132H207N37O40S6
Molecular Weight
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.02.08
3144.66988
SMILES
Canonical
1
1.7.6
OEChem
openeye.com
2012.02.08
CCC(C)C1C(=O)NCC(=O)NC2CSSCC3C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC4CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)C)CO)CO)C(C)CC)NC(=O)C5CCCN5C(=O)C(NC(=O)C(NC(=O)C(NC4=O)C(C)C)CC(=O)C6=CC=CC=C6N)C(C)CC)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)N7CCCC7C(=O)N3)C(C)CC)CC(=O)N)CCCNC(=N)N)CC8=CC=C(C=C8)O)C(C)C)CCCCN)CO)CCCCN)NC(=O)C(NC2=O)CO)CO)CCC(=O)O
SMILES
Isomeric
1
1.7.6
OEChem
openeye.com
2012.02.08
CC[C@H](C)[C@H]1C(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]4CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)C)CO)CO)[C@@H](C)CC)NC(=O)[C@@H]5CCCN5C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC4=O)C(C)C)CC(=O)C6=CC=CC=C6N)[C@@H](C)CC)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N7CCC[C@H]7C(=O)N3)[C@@H](C)CC)CC(=O)N)CCCNC(=N)N)CC8=CC=C(C=C8)O)C(C)C)CCCCN)CO)CCCCN)NC(=O)[C@@H](NC2=O)CO)CO)CCC(=O)O
Topological
Polar Surface Area
7
E_TPSA
3.396
Cactvs
xemistry.com
2012.02.08
1370
Weight
MonoIsotopic
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.02.08
3142.362531
215
31
31
0
0
0
0
0
1
1000