53377419
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
16
9
8
8
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
3
4
5
5
5
6
6
7
7
7
8
8
8
9
10
11
11
12
14
14
15
15
16
16
17
17
18
18
20
20
21
22
23
24
24
25
25
26
23
26
19
13
22
11
13
27
9
12
10
22
30
9
10
14
13
15
12
16
17
18
28
19
29
20
31
21
32
19
33
21
34
35
23
24
25
36
26
37
38
1
1
1
2
2
1
1
1
2
1
1
1
1
1
2
1
1
1
1
2
2
2
1
2
1
1
1
1
1
1
1
2
1
1
1
2
1
1
2
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
0.0658
4.6793
-0.8573
3.5985
-2.7615
-1.2105
1.4794
0.7542
-0.6634
1.7683
-3.3481
-2.5596
-1.4322
1.066
3.0943
-4.6947
-3.1413
2.3919
3.4061
-5.263
-4.4871
2.3782
1.7643
2.3794
1.4436
0.1493
-3.3313
0.2866
3.9385
0.4967
-5.3046
-2.5491
2.635
-6.3094
-4.93
3.4483
1.7064
-0.7513
-3.054
2.9755
2.6003
-1.5302
1.5809
0.626
-0.5173
1.8011
1.414
0.8443
0.7469
0.2695
1.9356
3.1545
1.2411
0.3944
-0.577
3.5513
2.5945
-0.4498
-0.9358
-1.5904
-2.932
-4.1637
-5.2215
-4.7582
1.9111
3.9118
0.5698
-0.753
0.767
-0.9621
4.6048
-0.7299
-1.594
-4.3077
-6.2692
-5.3388
0.3539
-0.6131
2.1391
-0.1129
1.3415
-0.7894
-0.015
-0.0974
0.0854
-0.1418
0.3865
-0.6602
1.2889
-0.2271
-0.3158
0.4962
-1.6095
-0.4007
-0.445
-0.4561
-1.5077
-0.0078
0.1739
0.2235
0.4116
0.4987
2.1148
-0.2016
-0.368
0.0987
1.3145
-2.4361
-0.5032
-0.3786
-2.2497
0.1301
0.4796
0.6404
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2012.05.21
032E798B00000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
74.1305
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
45.703
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10064457 181 18048597324195062765
10090160 65 18339074994602635325
108634 29 17764595704329062510
1100329 8 18410287056199823038
11014199 57 17762335816860551263
11069576 57 18270378539329335535
12107183 9 17909276780638657801
12156800 1 17402862997224397530
12553582 1 17977388235332623310
12788726 201 17560814225382613145
13004483 165 17472411054640168025
13009979 54 17844531006842485322
13052359 8 17977102689053775280
13140716 1 18339635737180334402
13540713 4 17335353009783185196
13692114 37 17910096242559364958
13785724 45 17766010398264409007
138480 1 18192991517499106358
13911987 19 18044388342203007444
14659021 117 17252582383543516090
14844126 61 16604907298259034146
16728300 4 15446092359976896427
16993438 75 17684932796925914459
17138139 8 17626926918683423631
19319366 153 18269548502523573623
19930381 70 18336265635283300939
20028762 73 18343297068262573990
20642791 105 17472691911611774896
20775438 99 17181603491995112196
21133410 171 16526332993915556995
21133410 52 18267559400264771054
21421861 104 18199766760284850385
21796203 349 17904798516474773074
2255824 54 18410011022497913326
3380486 145 17686065994061118792
4409770 3 17760933243960833866
5309563 4 18049161073139371503
5364581 5 17039483823894881946
550186 72 17687740538124109842
563151 97 18410866459841217564
59755656 520 18192428791395583972
7097593 13 17982738467408084761
9777508 108 17690840489833377680
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
504.96
7.96
6.57
1.17
7.66
7.26
0.19
-1.25
-1.87
-8.56
1.04
1.15
-0.46
-1.85
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1111.95
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
273.8
Conformer
RMSD
7
2012.05.21
0.8
Diverse Conformer
ID List
6
2012.05.21
1
12
22
8
17
20
7
11
15
13
18
6
19
23
5
14
16
9
4
21
24
10
2
3
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.05.21
38
1 -0.08
10 0.12
11 0.12
12 0.18
13 0.63
14 -0.15
15 -0.15
16 -0.15
17 -0.15
18 -0.15
19 0.19
2 -0.19
20 -0.15
21 -0.15
22 0.71
23 -0.05
24 -0.15
25 -0.15
26 -0.11
27 0.37
28 0.15
29 0.15
3 -0.57
30 0.37
31 0.15
32 0.15
33 0.15
34 0.15
35 0.15
36 0.15
37 0.15
38 0.15
4 -0.57
5 -0.55
6 -0.63
7 -0.55
8 0.09
9 0.36
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.05.21
4
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.05.21
9
1 3 acceptor
1 4 acceptor
1 5 donor
1 6 acceptor
1 7 donor
5 1 23 24 25 26 rings
6 11 12 16 17 20 21 rings
6 5 6 9 11 12 13 rings
6 8 10 14 15 18 19 rings
26
0
0
0
0
0
0
0
1
10