5329831 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 17 17 16 8 8 8 7 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 3 3 3 6 7 7 7 8 8 8 9 9 10 10 10 11 11 12 12 12 13 13 13 14 14 15 15 16 17 17 18 18 19 19 19 20 20 21 22 24 24 25 25 26 26 27 27 27 28 29 30 30 31 33 33 34 35 36 36 37 37 38 34 35 4 5 13 19 32 18 22 27 16 23 48 22 23 26 32 57 23 31 32 33 59 14 39 40 15 17 16 41 20 21 42 24 25 43 44 45 21 46 47 30 28 49 29 50 28 29 51 52 53 54 55 31 56 58 34 35 36 37 38 60 38 61 62 1 1 2 2 1 1 2 1 1 1 1 1 1 2 1 1 1 1 2 1 1 1 1 1 1 1 2 1 1 1 2 2 1 2 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 1 1 2 1 1 2 1 1 2 2 1 1 1 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 14.1244 15.8564 2.866 3.366 2.366 13.2583 8.9282 5.4641 7.1962 12.3923 6.3301 14.1244 3.732 3.732 4.5981 4.5981 2.866 9.7942 2 3.732 2.866 8.0622 6.3301 10.6603 9.7942 11.5263 8.9282 11.5263 10.6603 8.0622 7.1962 13.2583 14.9904 14.9904 15.8564 15.8564 16.7224 16.7224 4.3426 3.9441 5.135 2.3291 2.31 1.4631 1.69 3.732 2.3291 5.4641 10.6603 9.2573 8.3082 8.9282 9.5482 12.0632 10.6603 8.5991 12.3923 7.1962 14.1244 15.8564 17.2594 17.2594 -1.683 1.317 1.817 2.683 0.951 -1.183 -1.683 -1.683 -1.683 0.317 -0.183 0.317 1.317 0.317 -0.183 -1.183 -0.183 -1.183 2.317 -1.683 -1.183 -1.183 -1.183 -1.683 -0.183 -0.183 -2.683 -1.183 0.317 -0.183 0.317 -0.183 -0.183 -1.183 0.317 -1.683 -0.183 -1.183 1.2093 1.8996 0.127 0.127 2.8539 2.627 1.78 -2.303 -1.493 -2.303 -2.303 0.127 -2.683 -3.303 -2.683 -1.493 0.937 0.127 0.937 0.937 0.937 -2.303 0.127 -1.493 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 9 9 11 11 14 14 15 16 17 18 18 20 22 24 25 26 26 30 33 33 34 35 36 37 22 23 23 31 15 17 16 20 21 24 25 21 30 28 29 28 29 31 34 35 36 37 38 38 0 Compound Canonicalized 5 2011.04.04 1 Compound Complexity 7 E_COMPLEXITY 3.402 Cactvs xemistry.com 2012.05.21 860 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.402 Cactvs xemistry.com 2012.05.21 7 Count Hydrogen Bond Donor 5 E_NHDONORS 3.402 Cactvs xemistry.com 2012.05.21 3 Count Rotatable Bond 5 E_NROTBONDS 3.402 Cactvs xemistry.com 2012.05.21 8 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.402 Cactvs xemistry.com 2012.05.21 00000371E07BB0004600000000000000000000000000000000003C60C100000000000001D400001E06100000000C0AC55A24BFF097C8100AA80236677470C280293107B009D8203866988828E2E1DBD1C42408689402C8C8271080000E00008040008000100001008001000020000000000000 IUPAC Name Allowed 1 2.1.0 LexiChem openeye.com 2012.05.21 1-(2,6-dichlorophenyl)-3-[4-[methyl-[2-[3-(methylsulfonylmethyl)anilino]pyrimidin-4-yl]amino]phenyl]urea IUPAC Name CAS-like Style 1 2.1.0 LexiChem openeye.com 2012.05.21 1-(2,6-dichlorophenyl)-3-[4-[methyl-[2-[3-(methylsulfonylmethyl)anilino]-4-pyrimidinyl]amino]phenyl]urea IUPAC Name Preferred 1 2.1.0 LexiChem openeye.com 2012.05.21 1-(2,6-dichlorophenyl)-3-[4-[methyl-[2-[3-(methylsulfonylmethyl)anilino]pyrimidin-4-yl]amino]phenyl]urea IUPAC Name Systematic 1 2.1.0 LexiChem openeye.com 2012.05.21 1-[2,6-bis(chloranyl)phenyl]-3-[4-[methyl-[2-[[3-(methylsulfonylmethyl)phenyl]amino]pyrimidin-4-yl]amino]phenyl]urea IUPAC Name Traditional 1 2.1.0 LexiChem openeye.com 2012.05.21 1-(2,6-dichlorophenyl)-3-[4-[[2-[3-(mesylmethyl)anilino]pyrimidin-4-yl]-methyl-amino]phenyl]urea InChI Standard 1 1.0.4 InChI iupac.org 2012.05.21 InChI=1S/C26H24Cl2N6O3S/c1-34(20-11-9-18(10-12-20)31-26(35)33-24-21(27)7-4-8-22(24)28)23-13-14-29-25(32-23)30-19-6-3-5-17(15-19)16-38(2,36)37/h3-15H,16H2,1-2H3,(H,29,30,32)(H2,31,33,35) InChIKey Standard 1 1.0.4 InChI iupac.org 2012.05.21 NXPQZPWXVHIWGN-UHFFFAOYSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.05.21 5.1 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 570.100765 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 C26H24Cl2N6O3S Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 571.47816 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.05.21 CN(C1=CC=C(C=C1)NC(=O)NC2=C(C=CC=C2Cl)Cl)C3=NC(=NC=C3)NC4=CC=CC(=C4)CS(=O)(=O)C SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.05.21 CN(C1=CC=C(C=C1)NC(=O)NC2=C(C=CC=C2Cl)Cl)C3=NC(=NC=C3)NC4=CC=CC(=C4)CS(=O)(=O)C Topological Polar Surface Area 7 E_TPSA 3.402 Cactvs xemistry.com 2012.05.21 125 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 570.100765 38 0 0 0 0 0 0 0 1 9