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Compound Summary for: CID 5284616

Sirolimus

Also known as: rapamycin, Rapamune, 53123-88-9, (-)-Rapamycin, AY-22989, WY-090217, CHEBI:9168, NCGC00021305-05, Antibiotic AY 22989
Molecular Formula: C51H79NO13   Molecular Weight: 914.17186   InChIKey: QFJCIRLUMZQUOT-HPLJOQBZSA-N
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.   From: MeSH
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