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Compound Summary for: CID 5281081     Try the new version summary page


Also known as: Comtan; Comtess; Entacaponum; Entacapona; 130929-57-6; OR-611; Entacaponum [INN-Latin]; Entacapona [INN-Spanish]
Molecular Formula: C14H15N3O5   Molecular Weight: 305.286   InChIKey: JRURYQJSLYLRLN-BJMVGYQFSA-N
Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of levodopa and a decarboxylase inhibitor.   From: DrugBank
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