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Compound Summary for: CID 5280383     Try the new version summary page

Leukotriene A4

Also known as: LTA4; CHEBI:15651; 5S,6S-epoxy-7E,9E,11Z,14Z-eicosatetraenoic acid; (5S,6S,7E,9E,11Z,14Z)-5,6-Epoxyicosa-7,9,11,14-tetraenoate
Molecular Formula: C20H30O3   Molecular Weight: 318.4504   InChIKey: UFPQIRYSPUYQHK-WAQVJNLQSA-N
(2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate precursor 5-HPETE via the stereospecific removal of a proton at C-10 and dehydration. Its biological actions are determined primarily by its metabolites, i.e., LEUKOTRIENE B4 and cysteinyl-leukotrienes. Alternatively, leukotriene A4 is converted into LEUKOTRIENE C4 by glutathione-S-transferase or into 5,6-di-HETE by the epoxide-hydrolase. (From Dictionary of Prostaglandins and Related Compounds, 1990)   From: MeSH
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