5160
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
8
8
8
8
8
8
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
4
4
5
5
6
7
7
7
8
8
8
9
9
10
10
11
11
11
11
12
12
13
13
13
14
15
15
16
16
17
17
17
18
18
18
19
19
20
21
21
22
23
23
23
24
24
25
25
26
27
27
27
28
28
29
31
31
31
10
14
8
20
20
26
31
30
62
30
9
17
18
9
10
32
33
34
35
36
12
13
37
38
14
16
15
39
40
19
24
25
21
41
42
43
44
45
46
47
22
48
23
22
49
50
27
51
52
26
53
28
54
29
30
55
56
29
57
58
59
60
61
1
1
1
1
2
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
2
2
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
2
1
2
1
1
1
1
1
1
1
1
1
8
2
9
10
32
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
-2.5951
-0.3572
0.6642
3.6247
5.4972
4.0464
-2.4225
-1.5036
-1.2833
-2.7454
-1.0137
-2.4982
-0.5392
-3.226
0.9624
-3.1569
-2.4738
-2.3609
-4.6126
0.66
-4.5434
-5.2713
1.7842
1.6075
1.7053
2.9953
3.1653
3.093
3.738
4.2549
2.8048
-1.6348
-0.3489
-1.1074
-3.6555
-2.833
-0.5832
-0.5913
-0.9158
-0.9853
-2.6025
-2.591
-1.5717
-3.3423
-2.3845
-1.4612
-3.2353
-5.1944
-5.0566
-6.3512
1.7245
1.6156
0.9809
1.214
3.2641
3.3078
3.6715
4.8193
3.4705
2.1213
2.2782
6.1964
-0.229
-1.5594
-3.5237
0.3193
-1.545
0.1138
-3.435
-2.2978
-2.7074
-1.4326
2.0534
2.0201
2.5632
0.8825
2.5559
3.1433
-3.303
-4.8484
0.8683
-2.3067
3.1291
1.9915
-1.3797
1.4267
3.6789
1.4205
-1.999
3.6727
2.5435
-1.022
-0.7938
-3.1861
-3.2748
-1.7857
-1.9522
-1.197
2.6878
1.0612
3.5806
1.9548
4.0372
-2.2523
-3.6969
-3.8348
-4.9718
-5.3427
-5.3841
-0.0069
4.004
1.9814
-0.4668
-1.0925
0.5808
4.5636
-2.8833
-2.3037
4.5467
2.5443
-1.5822
-0.5457
-1.2002
-0.9042
-0.1604
0.817
1.4629
-2.1392
1.7933
2.3467
-1.6187
0.3819
-1.0762
0.586
0.5242
0.6799
-0.8504
0.331
-1.0017
1.18
-3.0763
-1.2402
0.482
1.3412
1.3311
0.9821
1.7508
-1.5062
-0.6371
-1.6462
1.5733
-0.777
-1.2816
1.9403
-2.4923
1.0121
-1.1854
-1.6495
0.268
1.6551
1.3118
0.7198
-1.0212
-1.6487
1.4534
-3.3645
-3.5584
-3.4808
-0.1528
-1.625
-1.6275
0.206
1.7194
1.0976
1.145
2.795
-1.7696
-0.2409
2.2122
0.5307
-0.4923
-1.3878
-2.8588
-3.3114
-1.6222
2.0441
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0000142800000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
83.9693
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
45.731
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10006869 2 18263940989370190603
10032420 55 14438399543703769964
1100329 8 18259989253673084472
11513181 2 17629182837043840487
11578080 2 16629974355105977634
12156800 1 17631441431400257798
12788726 201 18052260892780799911
14117953 113 17974285417840465189
14840074 17 18041843896391915688
14955137 171 18042412322481309210
15840311 113 16114290899721858777
18336668 15 17313948498890941472
19319366 153 17678203549745880462
2132832 1 18193816348909746726
21796203 349 17681305207856059952
23558518 356 18048332324549635588
23559900 14 18129962125322827148
25019877 29 17630304373485580127
445580 8 18190184481672182744
463206 1 17968387779514271080
474144 1 17896616002453856688
57091435 65 17970924253680424368
5895379 119 18343021112112668422
6287921 2 17550115762300483929
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
597.77
9.26
6.35
2.59
0.54
2.68
0.65
-3.99
-3.15
-3.23
1.92
2.36
2
-5.58
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1230.299
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
343.5
Conformer
RMSD
7
2009.12.11
1.2
Diverse Conformer
ID List
6
2012.02.08
1
178
8
243
73
206
215
35
222
263
93
284
280
228
25
140
265
64
262
104
63
157
273
54
227
238
187
218
110
148
256
139
102
75
266
92
153
249
111
239
34
162
69
42
230
285
250
15
159
113
116
38
247
121
163
182
26
151
88
211
260
183
89
128
170
114
176
267
180
108
136
199
201
9
198
56
122
61
11
138
191
251
194
281
255
107
141
269
74
221
23
261
200
51
205
203
90
167
195
277
190
6
188
149
233
28
216
196
131
184
177
99
275
87
57
105
202
143
244
10
145
283
17
33
207
101
179
118
84
171
181
103
175
47
43
259
29
234
21
46
97
127
264
24
254
31
164
204
27
271
226
245
91
100
96
235
62
2
45
147
241
214
49
223
94
258
135
40
115
231
210
112
32
20
72
276
76
150
268
193
52
197
81
18
155
237
185
173
146
209
117
225
156
79
137
119
16
282
58
3
133
106
242
4
154
144
217
70
246
77
60
67
65
71
158
123
212
78
82
50
55
13
192
132
142
125
41
109
129
53
257
208
172
166
37
220
213
66
12
5
236
7
48
248
152
68
30
224
189
169
168
44
219
186
274
36
165
278
272
134
86
270
80
14
252
83
161
22
95
124
279
98
85
229
19
174
130
120
59
240
253
232
39
126
160
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
40
1 -0.36
10 0.28
11 0.14
12 -0.14
13 0.14
14 0.08
15 -0.14
16 -0.15
17 0.27
18 0.27
19 -0.15
2 -0.43
20 0.66
21 -0.15
22 -0.15
23 0.06
24 -0.15
25 -0.15
26 0.08
27 0.06
28 -0.15
29 -0.15
3 -0.57
30 0.66
31 0.28
4 -0.36
41 0.15
48 0.15
49 0.15
5 -0.65
50 0.15
53 0.15
54 0.15
57 0.15
58 0.15
6 -0.57
62 0.5
7 -0.81
8 0.28
9 0.27
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
14
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
9
1 1 acceptor
1 3 acceptor
1 4 acceptor
1 5 acceptor
1 6 acceptor
1 7 cation
3 5 6 30 anion
6 12 14 16 19 21 22 rings
6 15 24 25 26 28 29 rings
31
1
0
1
0
0
0
0
1
1