50919373 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 17 8 8 8 8 8 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 3 4 5 5 6 6 7 7 7 8 8 8 9 9 10 10 11 11 11 11 12 12 12 13 13 14 14 14 15 15 15 17 17 18 20 20 21 22 22 23 23 24 25 25 26 27 27 28 28 29 30 30 31 31 32 32 34 34 36 36 36 37 37 37 35 16 54 16 19 26 36 33 37 13 19 48 18 20 21 17 18 24 29 12 13 38 39 14 15 40 16 41 42 46 47 43 44 45 19 21 22 23 25 49 26 27 24 28 31 29 50 30 32 51 34 52 53 33 55 35 56 33 57 35 58 59 60 61 62 63 64 1 1 1 2 2 1 1 1 1 1 1 1 1 1 1 1 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 2 1 1 1 1 2 1 1 2 1 2 1 1 2 1 2 1 1 1 1 1 1 1 1 1 1 1 13 7 11 16 41 1 1 1 3 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 10.8865 8.8063 7.224 9.4387 5.0611 2.7431 8.0374 7.3564 6.8564 7.3564 9.6197 10.2075 8.6252 11.2021 9.8008 8.2185 7.8564 6.5474 8.4442 7.3564 8.1654 5.5963 8.2224 8.2224 6.4904 4.8532 5.3884 9.1164 6.4904 3.9021 9.1164 4.4374 3.6942 10.0224 10.0224 4.3179 2 10.177 9.4488 10.4597 8.8774 11.2669 9.2344 9.5486 10.3672 11.8187 11.1372 7.4208 8.7551 5.9534 5.8492 9.1092 5.9534 8.5541 3.4414 9.1092 4.3084 10.5582 3.9031 3.8572 4.7328 1.5851 1.5392 2.4149 4.6865 -4.1306 -3.4261 -0.581 -0.2637 2.3106 -1.599 1.6624 0.1235 4.6624 -2.3035 -3.1126 -2.4081 -3.008 -4.0261 -3.3216 0.1235 1.0746 -0.6855 2.6624 1.0746 1.3836 3.1624 4.1624 3.1624 0.7145 2.3617 2.6277 4.1624 1.0235 4.697 2.6708 2.0016 3.1415 4.1832 -0.9328 1.6415 -2.0317 -1.7076 -2.5462 -1.8417 -3.6246 -3.7739 -4.5925 -4.2783 -2.9432 -2.3914 -1.6638 1.2662 2.8524 2.7766 2.0077 4.4724 -4.697 0.6086 5.317 3.2772 2.8295 -0.4721 -1.3477 -1.3936 2.1023 1.2266 1.1808 8 8 8 8 8 8 5 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 9 9 10 10 13 17 20 20 22 22 23 23 24 25 26 27 28 30 31 32 34 18 21 17 18 24 29 7 21 23 25 26 27 24 28 31 29 30 32 34 33 35 33 35 0 Compound Canonicalized 5 2011.04.04 1 Compound Complexity 7 E_COMPLEXITY 3.402 Cactvs xemistry.com 2012.05.21 788 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.402 Cactvs xemistry.com 2012.05.21 7 Count Hydrogen Bond Donor 5 E_NHDONORS 3.402 Cactvs xemistry.com 2012.05.21 2 Count Rotatable Bond 5 E_NROTBONDS 3.402 Cactvs xemistry.com 2012.05.21 9 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.402 Cactvs xemistry.com 2012.05.21 00000371E07BB8000400000000000000000000000001600000003C6080000000000000B1FC00001E02100800000D2EC19F263FDEF7CC1600A80337F77C0082882D3737A009D8A1BE7ED88E6FFAC5FBFB9474A86FD617D8E8E798F0AE0E24000008020A00004800001004140000000000000000 IUPAC Name Allowed 1 2.1.0 LexiChem openeye.com 2012.05.21 (2S)-2-[[1-(7-chloro-4-quinolyl)-2-(2,4-dimethoxyphenyl)imidazole-4-carbonyl]amino]-4-methyl-pentanoic acid IUPAC Name CAS-like Style 1 2.1.0 LexiChem openeye.com 2012.05.21 (2S)-2-[[[1-(7-chloro-4-quinolinyl)-2-(2,4-dimethoxyphenyl)-4-imidazolyl]-oxomethyl]amino]-4-methylpentanoic acid IUPAC Name Preferred 1 2.1.0 LexiChem openeye.com 2012.05.21 (2S)-2-[[1-(7-chloroquinolin-4-yl)-2-(2,4-dimethoxyphenyl)imidazole-4-carbonyl]amino]-4-methylpentanoic acid IUPAC Name Systematic 1 2.1.0 LexiChem openeye.com 2012.05.21 (2S)-2-[[1-(7-chloranylquinolin-4-yl)-2-(2,4-dimethoxyphenyl)imidazol-4-yl]carbonylamino]-4-methyl-pentanoic acid IUPAC Name Traditional 1 2.1.0 LexiChem openeye.com 2012.05.21 (2S)-2-[[1-(7-chloro-4-quinolyl)-2-(2,4-dimethoxyphenyl)imidazole-4-carbonyl]amino]-4-methyl-valeric acid InChI Standard 1 1.0.4 InChI iupac.org 2012.05.21 InChI=1S/C27H27ClN4O5/c1-15(2)11-21(27(34)35)31-26(33)22-14-32(23-9-10-29-20-12-16(28)5-7-18(20)23)25(30-22)19-8-6-17(36-3)13-24(19)37-4/h5-10,12-15,21H,11H2,1-4H3,(H,31,33)(H,34,35)/t21-/m0/s1 InChIKey Standard 1 1.0.4 InChI iupac.org 2012.05.21 MSSVRMZTTHGMIT-NRFANRHFSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.05.21 5.1 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 522.166998 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 C27H27ClN4O5 Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 522.98008 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.05.21 CC(C)CC(C(=O)O)NC(=O)C1=CN(C(=N1)C2=C(C=C(C=C2)OC)OC)C3=C4C=CC(=CC4=NC=C3)Cl SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.05.21 CC(C)C[C@@H](C(=O)O)NC(=O)C1=CN(C(=N1)C2=C(C=C(C=C2)OC)OC)C3=C4C=CC(=CC4=NC=C3)Cl Topological Polar Surface Area 7 E_TPSA 3.402 Cactvs xemistry.com 2012.05.21 116 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 522.166998 37 1 1 0 0 0 0 0 1 2