50919365 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 8 8 8 8 8 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 4 4 5 5 6 6 6 7 7 7 8 8 9 9 10 10 10 10 11 11 11 12 12 13 13 13 14 14 14 15 16 16 19 19 20 21 21 22 22 23 23 24 25 26 27 27 28 29 29 30 30 31 31 32 32 33 34 35 35 35 36 36 36 17 54 17 18 25 35 26 36 12 18 47 15 19 20 15 16 24 28 11 12 37 38 13 14 39 17 40 41 45 46 42 43 44 21 18 20 22 23 48 25 26 24 27 28 49 31 29 30 32 50 51 33 52 33 53 34 55 34 56 57 58 59 60 61 62 63 64 1 1 2 2 1 1 1 1 1 1 1 1 1 1 2 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 2 1 1 2 1 1 2 1 2 1 1 1 2 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 12 6 10 17 40 1 1 1 3 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 7.1933 5.611 7.8258 3.5962 4.3164 6.4245 5.7435 5.2435 5.7435 8.0068 8.5946 7.0123 9.5891 8.1879 4.9344 6.2435 6.6056 6.8312 5.7435 6.5525 3.9563 6.6095 4.8774 6.6095 3.2872 3.6472 7.5034 4.8774 2.309 2.6691 7.5034 8.4095 2 8.4095 2.927 4.0074 8.5641 7.8359 7.978 6.3957 9.6539 7.6215 7.9357 8.7543 10.2057 9.5243 5.8079 7.1421 4.3405 7.4963 4.3405 1.8942 2.4775 6.9412 7.4963 8.9452 1.3936 8.9452 3.3878 2.5122 2.4663 3.4177 3.8158 4.597 -4.1306 -3.4261 -0.581 2.5609 -0.8275 -1.599 1.6624 0.1235 4.6624 -2.3035 -3.1126 -2.4081 -3.008 -4.0261 1.0746 0.1235 -3.3216 -0.6855 2.6624 1.0746 0.8667 3.1624 3.1624 4.1624 1.6098 -0.0843 2.6277 4.1624 1.4019 -0.2922 4.697 3.1415 0.4508 4.1832 3.304 -1.7786 -2.0317 -1.7076 -3.1774 -2.4729 -3.6246 -3.7739 -4.5925 -4.2783 -2.9432 -2.3914 -1.6638 1.2662 2.8524 2.0077 4.4724 1.8626 -0.8819 -4.697 5.317 2.8295 0.3219 4.4952 3.7189 3.7648 2.8892 -1.587 -2.3683 -1.9702 8 8 8 8 8 8 5 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 7 7 8 8 9 9 12 16 19 19 21 21 22 22 23 24 25 26 27 29 30 31 32 15 20 15 16 24 28 6 20 22 23 25 26 24 27 28 31 29 30 32 33 33 34 34 0 Compound Canonicalized 5 2011.04.04 1 Compound Complexity 7 E_COMPLEXITY 3.402 Cactvs xemistry.com 2012.05.21 740 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.402 Cactvs xemistry.com 2012.05.21 7 Count Hydrogen Bond Donor 5 E_NHDONORS 3.402 Cactvs xemistry.com 2012.05.21 2 Count Rotatable Bond 5 E_NROTBONDS 3.402 Cactvs xemistry.com 2012.05.21 9 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.402 Cactvs xemistry.com 2012.05.21 00000371E07BB8000000000000000000000000000001600000003C6080000000000000B1FC00001E00100800000D2CC19F063FDEF7CC1600A80337F77C0082882D3732A009D8A1BE7CD88E6FFAC4F9FB9474A86FD617D8E8E798E0AC0E00000008000A00000000001000140000000000000000 IUPAC Name Allowed 1 2.1.0 LexiChem openeye.com 2012.05.21 (2S)-2-[[2-(2,6-dimethoxyphenyl)-1-(4-quinolyl)imidazole-4-carbonyl]amino]-4-methyl-pentanoic acid IUPAC Name CAS-like Style 1 2.1.0 LexiChem openeye.com 2012.05.21 (2S)-2-[[[2-(2,6-dimethoxyphenyl)-1-(4-quinolinyl)-4-imidazolyl]-oxomethyl]amino]-4-methylpentanoic acid IUPAC Name Preferred 1 2.1.0 LexiChem openeye.com 2012.05.21 (2S)-2-[[2-(2,6-dimethoxyphenyl)-1-quinolin-4-ylimidazole-4-carbonyl]amino]-4-methylpentanoic acid IUPAC Name Systematic 1 2.1.0 LexiChem openeye.com 2012.05.21 (2S)-2-[[2-(2,6-dimethoxyphenyl)-1-quinolin-4-yl-imidazol-4-yl]carbonylamino]-4-methyl-pentanoic acid IUPAC Name Traditional 1 2.1.0 LexiChem openeye.com 2012.05.21 (2S)-2-[[2-(2,6-dimethoxyphenyl)-1-(4-quinolyl)imidazole-4-carbonyl]amino]-4-methyl-valeric acid InChI Standard 1 1.0.4 InChI iupac.org 2012.05.21 InChI=1S/C27H28N4O5/c1-16(2)14-19(27(33)34)30-26(32)20-15-31(21-12-13-28-18-9-6-5-8-17(18)21)25(29-20)24-22(35-3)10-7-11-23(24)36-4/h5-13,15-16,19H,14H2,1-4H3,(H,30,32)(H,33,34)/t19-/m0/s1 InChIKey Standard 1 1.0.4 InChI iupac.org 2012.05.21 KQEFWOPYRIREIY-IBGZPJMESA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.05.21 4.5 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 488.20597 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 C27H28N4O5 Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 488.53502 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.05.21 CC(C)CC(C(=O)O)NC(=O)C1=CN(C(=N1)C2=C(C=CC=C2OC)OC)C3=CC=NC4=CC=CC=C43 SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.05.21 CC(C)C[C@@H](C(=O)O)NC(=O)C1=CN(C(=N1)C2=C(C=CC=C2OC)OC)C3=CC=NC4=CC=CC=C43 Topological Polar Surface Area 7 E_TPSA 3.402 Cactvs xemistry.com 2012.05.21 116 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 488.20597 36 1 1 0 0 0 0 0 1 2