rofecoxib - PubChem

rofecoxib - Compound Summary (CID 5090) Also known as: Vioxx, Ceoxx, 162011-90-7, MK 966, Vioxx (trademark), MK 996, MK-966, 4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one, MK 0966 Molecular Formula: C₁₇H₁₄O₄S Molecular Weight: 314.35566 InChIKey: RZJQGNCSTQAWON-UHFFFAOYSA-N On September 30, 2004, Merck voluntarily withdrew rofecoxib from the market because of concerns about increased risk of heart attack and stroke associated with long-term, high-dosage use. From: DrugBank View the conformer with web-based 3D viewer View the conformer with Pc3D viewer application Download Pc3D viewer application 2D ASN.1 Text: Display 2D ASN.1 Text: Save 2D ASN.1 Binary: Save 3D ASN.1 Text: Display 3D ASN.1 Text: Save 3D ASN.1 Binary: Save 2D XML: Display 2D XML: Save 3D XML: Display 3D XML: Save 2D SDF: Display 2D SDF: Save 3D SDF: Display 3D SDF: Save BioActivity, this compound BioActivity, with similar compounds BioActivity, with similar conformers
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Identification Help top of page Related Records Help top of page show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)show first sub-section only Use and Manufacturing Help top of page show all 3 sub-sections (Patents, Methods of Manufacturing, Formulations/Preparations)show first sub-section only Pharmacology Help top of page show all 3 sub-sections (Pharmacological Action, Therapeutic Uses, Drug Warning)show first sub-section only Biomedical Effects and Toxicity Help top of page show all 8 sub-sections (Absorption, Distribution and Excretion, Metabolism/Metabolites, Biological Half-Life ...)show first sub-section only Safety and Handling Help top of page Literature Help top of page show all 2 sub-sections (Depositor Provided PubMed Citations, NLM Curated PubMed Citations)show first sub-section only Patents Help top of page Biomolecular Interactions and Pathways Help top of page Biological Test Results Help top of page Data Analysis Data Download BioActivity Summary: This Compound with Similar Compounds with Similar Conformers Classification Help top of page show all 2 sub-sections (Ontologies, Substance Categorization Classification)show first sub-section only Chemical and Physical Properties Help top of page show all 6 sub-sections (Color/Form, Octanol/Water Partition Coefficient, Solubilities, Vapor Pressure, Other Chemical/Physical Properties ...)show first sub-section only

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