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276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 16 16 16 16 16 16 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 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150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 15.3919 24.7856 14.5258 24.1905 9.1688 9.9563 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14.3872 6.6203 5.0637 14.9437 15.2227 11.3797 6.9499 6.8277 17.8027 5.1923 4.0927 16.9601 7.1369 16.9943 11.6933 9.6158 5.9939 20.3702 10.8046 17.9475 11.3343 12.6011 14.5025 15.8411 5.8415 16.1458 3.4003 5.8994 17.0416 18.745 5.2617 17.3682 10.5856 9.2419 8.9996 11.5154 7.6065 16.18 10.2795 11.2455 17.2229 18.9262 15.0957 9.6372 12.2685 6.9977 8.2518 8.0094 8.6065 18.1652 14.2533 7.6355 10.0207 12.8264 11.8459 7.3804 8.8884 9.4374 7.94 8.489 10.8497 6.7717 7.7403 24.5852 26.5327 26.0222 24.4916 25.2897 26.1006 26.5634 23.8148 22.7277 24.9375 24.3136 22.4294 22.2334 22.333 23.2041 26.3127 24.1201 24.9243 25.2737 20.139 26.3828 25.2771 20.1195 21.2257 19.3364 26.4598 16.7783 26.2955 22.5604 20.6844 15.846 16.5122 25.8818 24.7029 18.3481 23.7651 21.8891 23.4295 18.9185 15.784 18.8725 17.688 16.1619 15.7348 18.9884 13.1429 14.1487 24.0845 23.0787 18.6033 12.7012 10.1172 7.1778 19.6275 18.8934 23.1758 19.0628 17.2615 11.9824 18.2902 10.5036 7.8625 8.8861 10.381 22.1082 20.7468 21.2858 20.5942 18.7175 19.0469 19.8595 16.9933 11.3988 6.1708 6.3896 11.1443 9.226 7.7926 6.0064 5.241 18.2414 17.7244 10.7343 10.4158 9.5989 8.7027 8.1546 8.8389 6.5545 7.0974 16.3622 19.7848 4.0659 10.253 10.6389 14.3204 4.8134 5.5788 15.352 7.569 7.0262 6.2931 7.0555 6.0381 5.7002 4.9303 4.343 3.5775 16.328 18.9754 17.6008 13.6133 11.6933 6.276 5.4992 20.9301 20.6365 19.8103 10.3427 10.9826 10.669 10.7211 13.9461 14.2289 15.0588 15.5675 16.3975 16.1147 5.3022 6.0491 15.5393 15.914 3.15 3.9154 4.9796 5.7564 16.4574 19.2169 17.9432 17.6 16.7931 15.7827 11.071 10.29 12.1786 9.624 9.2314 7.8438 7.1367 16.7996 16.2011 15.5603 10.7179 16.751 19.5105 11.6696 11.2546 6.5789 6.4748 8.0199 7.6274 18.2775 2.2564 2 4.5933 9.1531 3.8518 4.167 14.1969 14.6223 10.6384 10.0747 12.4448 11.7918 13.0588 7.7993 7.9033 9.0123 9.9016 7.4758 8.3651 6.2633 7.1522 8.8943 9.8094 10.7827 6.7769 -0.666 9.8628 -0.166 10.6664 -9.5353 -9.99 -0.0402 2.7717 -1.8662 6.1039 -2.3965 6.3731 -2.613 1.808 -1.7224 -5.7712 1.5816 -8.0158 2.0265 -10.1741 -8.6998 13.8219 0.651 -4.9659 -10.7777 4.593 -1.8572 -2.5192 14.2067 -11.4974 -11.8707 8.2942 -13.2671 13.2185 4.303 -10.8606 -10.8775 11.2541 -15.0884 9.7522 -14.034 1.4211 -0.5126 4.0987 -1.3821 7.077 -2.0717 3.022 -4.7073 -5.3146 1.1764 -7.339 12.4948 2.8431 -6.7045 0.3911 -9.4086 -10.4985 -1.4717 -4.0168 13.2336 -10.477 5.7476 12.7605 -11.5107 -10.9468 8.6797 -6.5554 -12.361 0.4225 11.1539 11.4776 2.251 1.9759 0.6403 0.9825 0.0263 0.6749 -0.904 3.1491 -1.0514 -1.6868 -0.9318 -1.9817 -1.2234 5.0822 -2.106 6.0812 -2.7746 -1.4049 -1.2913 8.0512 -2.4648 -3.7529 -1.0435 8.9856 -3.1334 -4.4214 5.5916 -4.1117 -2.9148 0.3456 -3.8005 1.3447 -2.4344 0.4472 11.3815 -6.4981 1.1623 -5.6138 -8.2914 -6.375 11.9948 -7.1729 1.966 0.786 -8.9646 -7.532 1.0499 1.5919 -9.7914 -7.0499 -8.0939 -8.1165 -8.8119 -5.8287 3.7775 -0.7515 -5.5899 12.8722 -9.1467 1.4821 2.5076 -0.1256 13.12 -0.458 3.7434 -10.2512 -4.9256 -6.3114 -11.0821 -9.8922 4.7517 0.5167 -3.1241 -10.1301 -10.2397 -6.0726 13.0522 -2.2689 14.0516 -10.5107 3.8833 0.8102 14.0231 -10.3178 13.2108 6.7466 -10.5642 -11.9794 -11.5233 -3.2902 14.5808 -6.7942 -10.9468 -10.7788 -10.4649 0.129 14.979 7.4095 4.8108 3.0958 7.73 -11.6539 15.5803 -12.1022 -12.361 -11.7622 -11.4483 12.3413 7.0926 9.5778 -12.4473 4.9507 3.2356 -11.6539 -12.097 11.8024 4.1631 -11.1363 10.4077 10.4841 -13.3712 7.7554 6.1127 7.4386 5.7957 10.5712 -14.1645 6.4587 3.0144 1.9327 2.5864 0.3098 0.0838 0.3812 1.0695 -0.099 -0.8126 -0.9276 -0.4316 -1.0564 -1.301 -2.1722 -2.0726 3.9451 -2.2091 -2.5584 -1.7542 -1.83 4.702 5.1526 -2.1569 -1.7239 -1.9995 7.1754 -1.9725 8.5698 -1.8583 -3.9449 -1.4456 -0.4547 8.9152 8.7257 -1.8962 -2.9414 -5.028 -4.5262 3.4928 0.6778 -4.0406 -3.8942 1.9357 1.2627 -4.7093 0.2664 0.9099 11.5623 10.9189 -6.8351 0.3815 -4.8886 -8.8125 -6.0929 -5.7823 12.7002 -7.2492 2.4275 1.7791 -7.6186 1.3884 -9.1272 -8.5135 1.66 13.0516 -7.6652 -6.9736 -6.4346 -7.8523 -8.6649 -8.3355 -9.3464 2.5832 -6.1023 -6.9171 3.363 0.927 -0.2311 -5.0227 -5.2448 -9.1419 -8.5353 2.2585 3.0753 2.7568 2.0983 1.414 0.8658 -0.4897 -1.0733 -9.9065 13.7201 -11.0974 3.2337 4.3625 -10.8676 -6.8786 -6.6565 -10.6155 0.5484 1.1319 -2.81 -1.1323 -3.9459 -9.8841 -9.6778 -5.5054 -5.7276 13.6204 13.853 13.9231 -11.0877 -9.6607 1.3622 1.1839 13.7568 14.583 14.2894 -10.7313 -9.7239 5.7335 6.6552 -11.7058 -12.5358 -12.253 -12.0797 -11.7969 -10.967 -3.596 -3.8744 14.7093 14.0058 -7.3614 -7.1392 -0.423 -0.2447 -10.5712 -10.0627 14.7472 15.5541 15.2109 13.3398 7.7952 7.9544 -11.8965 5.2991 2.5208 -12.2267 -10.374 15.5591 16.1999 15.6014 -11.6638 -12.1644 -11.6559 9.7383 8.9137 -11.9902 -12.7804 5.5257 2.7473 -12.7067 -5.9599 -7.0028 -2.6222 -12.9599 0.0002 1.0268 12.4199 11.3042 -11.0822 -10.5186 10.6446 11.1017 11.5972 -13.8283 -13.038 8.3629 5.7017 7.8496 5.1882 3.8147 6.2622 -10.2786 11.5316 11.9854 -15.5803 5 5 6 6 8 8 6 5 8 8 8 8 6 6 5 6 6 5 6 5 5 5 5 6 5 8 8 6 6 5 8 8 5 8 8 8 8 6 5 8 8 8 8 6 8 8 8 8 8 8 73 77 79 85 89 89 91 92 93 94 97 98 102 108 109 111 113 116 125 126 127 128 135 138 145 146 146 149 151 152 153 153 158 166 167 171 172 174 176 178 179 181 181 182 184 185 194 195 196 197 201 208 82 87 93 94 227 228 97 98 100 100 104 112 251 253 256 120 131 129 137 136 155 141 162 166 167 309 169 313 171 172 170 178 179 184 185 183 190 187 187 194 195 192 189 189 196 197 200 200 0 Compound Canonicalized 5 2010.09.21 0 Compound Complexity 7 E_COMPLEXITY 3.396 Cactvs xemistry.com 2012.02.08 6470 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.396 Cactvs xemistry.com 2012.02.08 43 Count Hydrogen Bond Donor 5 E_NHDONORS 3.396 Cactvs xemistry.com 2012.02.08 35 Count Rotatable Bond 5 E_NROTBONDS 3.396 Cactvs xemistry.com 2012.02.08 32 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.396 Cactvs xemistry.com 2012.02.08 00000371F07FFE007000000000000000000000000001600000003060C1800000000000015400001E04100800000D2CE5D806B20E83C00200880221D218000200002020000888818E08880A763E82D13394700026F611989807BDDFA28E20000000000000004000000000000000000000000000 InChI Standard 1 1.0.4 InChI iupac.org 2012.02.08 InChI=1S/C128H187N31O35S6/c1-12-68(9)103-127(193)136-70(11)105(171)151-88-59-195-196-61-90-120(186)150-87(58-162)118(184)152-91-62-198-200-64-93(153-117(183)86(57-161)149-110(176)78(41-42-100(169)170)137-96(165)52-134-108(88)174)123(189)157-101(66(5)6)125(191)147-82(48-72-30-19-15-20-31-72)114(180)142-79(46-65(3)4)106(172)132-53-97(166)138-89(119(185)145-83(49-73-32-21-16-22-33-73)115(181)158-104(69(10)13-2)128(194)159-45-27-36-94(159)124(190)135-54-98(167)139-90)60-197-199-63-92(154-126(192)102(67(7)8)156-111(177)77(35-24-26-44-130)140-116(182)85(56-160)148-109(175)76(141-121(91)187)34-23-25-43-129)122(188)144-81(50-74-37-39-75(163)40-38-74)112(178)143-80(47-71-28-17-14-18-29-71)113(179)146-84(51-95(131)164)107(173)133-55-99(168)155-103/h14-22,28-33,37-40,65-70,76-94,101-104,160-163H,12-13,23-27,34-36,41-64,129-130H2,1-11H3,(H2,131,164)(H,132,172)(H,133,173)(H,134,174)(H,135,190)(H,136,193)(H,137,165)(H,138,166)(H,139,167)(H,140,182)(H,141,187)(H,142,180)(H,143,178)(H,144,188)(H,145,185)(H,146,179)(H,147,191)(H,148,175)(H,149,176)(H,150,186)(H,151,171)(H,152,184)(H,153,183)(H,154,192)(H,155,168)(H,156,177)(H,157,189)(H,158,181)(H,169,170)/t68-,69-,70-,76-,77-,78-,79-,80-,81-,82-,83-,84+,85-,86-,87-,88-,89-,90-,91-,92-,93+,94-,101-,102-,103-,104-/m0/s1 InChIKey Standard 1 1.0.4 InChI iupac.org 2012.02.08 AXGAZCWAIVSFHO-OHTGTQMRSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.02.08 -3.6 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.02.08 2911.216368 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.02.08 C128H187N31O35S6 Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.02.08 2912.43108 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.02.08 CCC(C)C1C(=O)NC(C(=O)NC2CSSCC3C(=O)NC(C(=O)NC4CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N1)CC(=O)N)CC5=CC=CC=C5)CC6=CC=C(C=C6)O)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC4=O)CCCCN)CO)CCCCN)C(C)C)C(=O)NC(C(=O)NC(C(=O)N7CCCC7C(=O)NCC(=O)N3)C(C)CC)CC8=CC=CC=C8)CC(C)C)CC9=CC=CC=C9)C(C)C)NC(=O)C(NC(=O)C(NC(=O)CNC2=O)CCC(=O)O)CO)CO)C SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.02.08 CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H]4CSSC[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)NCC(=O)N1)CC(=O)N)CC5=CC=CC=C5)CC6=CC=C(C=C6)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC4=O)CCCCN)CO)CCCCN)C(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N7CCC[C@H]7C(=O)NCC(=O)N3)[C@@H](C)CC)CC8=CC=CC=C8)CC(C)C)CC9=CC=CC=C9)C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC2=O)CCC(=O)O)CO)CO)C Topological Polar Surface Area 7 E_TPSA 3.396 Cactvs xemistry.com 2012.02.08 1170 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.02.08 2910.213013 200 26 26 0 0 0 0 0 1 1001