495479
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
15
15
8
8
8
8
8
8
8
8
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
2
3
3
4
4
5
6
7
8
9
10
11
11
11
12
12
13
13
14
14
15
15
16
16
16
17
17
17
18
18
18
19
19
20
20
20
21
21
5
7
8
6
9
10
11
13
12
13
14
15
18
19
20
21
12
14
22
15
23
16
17
24
25
26
27
28
29
30
31
32
33
19
34
35
36
37
21
38
39
40
41
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
11
3
12
14
22
3
1
12
4
11
15
23
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
-4.0203
4.0204
-1.174
1.1738
-2.8641
2.8643
-4.6044
-5.1712
4.6044
5.1715
-0.6801
0.6803
-0.0002
-1.6383
1.6384
0.0597
-0.0605
-5.6227
-6.2643
5.6227
6.2645
-0.5981
0.5983
-1.207
-1.8172
1.2071
1.817
0.9508
-0.8324
0.109
0.8314
-0.1097
-0.9519
-6.3346
-5.1531
-6.8129
-6.9431
6.3345
5.1531
6.8131
6.9432
1.7577
1.7575
-1.5544
-1.5548
0.7106
0.7101
0.9406
1.2734
0.9412
1.2726
-0.2416
-0.2419
-2.3824
0.8044
0.8044
-3.2421
-3.2413
0.0337
0.7093
0.0341
0.7089
-0.1685
-0.1693
1.8047
0.625
1.8047
0.6257
-3.8783
-3.8698
-2.6118
-3.8693
-2.6105
-3.8772
-0.1436
-0.9189
0.004
1.5162
-0.1426
-0.9187
0.0032
1.516
-0.0759
0.0766
-0.046
0.0452
-0.5103
0.5104
1.2105
-1.1264
-1.2105
1.1265
-0.3342
0.3342
-0.0001
0.1988
-0.1983
-1.2562
1.2567
0.7853
-0.402
-0.786
0.4017
-1.4263
1.4264
0.0689
1.2674
-0.0679
-1.2672
-1.2606
-1.3513
-2.1516
1.3523
2.1517
1.2613
1.5965
0.5109
-1.033
-0.0992
-1.5975
-0.5122
1.0322
0.0993
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
00078F7700000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
41.4859
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
30.488
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
11646440 116 18201728365753282169
12516196 113 8286198344649306277
13004483 165 9295020015846811564
13533116 47 17846501379757647198
13631057 29 18129371761484075439
13673619 4 12613022861315905224
13685833 64 9871742512358378941
13740256 8 10231743505559985101
14251752 14 13110970799266827385
15183329 4 16056882420351839988
15849732 13 17894634764400304548
173720 79 18186799184302266202
17539 30 17769644627027065614
17980427 23 13551471424210922863
18222031 100 10737287960941932120
20197701 30 18411136939399989154
204376 136 18408885144287362217
20567600 254 18335415755691559261
20645477 70 18196082254250288919
21054139 6 18340759442896712439
21236236 1 18341048640019106887
21521239 73 17775564212994319062
22182313 1 18197243457802406575
22224240 67 18409167732029887377
23198884 109 16415481554093430281
23402539 116 18201714097897843644
23536379 177 15770061613796132396
23559900 14 18131351960435052080
25147074 1 18338495504688394243
3009799 131 9943529583453903337
314173 85 7925634422779159093
335352 9 18411983551554996198
3759504 43 18259986010820054667
38695281 34 18201719522489148015
474229 33 18409450301954200513
495365 180 17489861653599708522
5104073 3 18115877291851229001
5385378 56 18339086973287289355
559249 180 18410006659602600178
59755656 215 18410859824131491526
59755656 520 18412537730151575095
6669772 16 18272935986085111366
9971528 1 7925620082263055687
9996256 80 18341894121189290975
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
392.91
14.66
2.9
1.08
0
3.49
0
-11.18
0
0
0
0
0.27
0.5
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
777.494
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
237.3
Conformer
RMSD
7
2009.12.11
1.2
Diverse Conformer
ID List
6
2012.02.08
1
25
8
28
27
30
12
38
9
34
18
5
35
39
45
10
26
37
4
17
15
29
31
41
7
43
11
23
40
14
6
22
13
24
44
32
2
20
36
16
21
3
19
33
42
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.05.21
19
1 0.3
10 -0.38
11 0.28
12 0.28
13 0.56
14 0.28
15 0.28
18 0.28
19 0.28
2 0.3
20 0.28
21 0.28
3 -0.56
4 -0.56
5 -0.38
6 -0.38
7 -0.38
8 -0.38
9 -0.38
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
9
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.05.21
6
1 3 acceptor
1 4 acceptor
3 13 16 17 hydrophobe
5 1 7 8 18 19 rings
5 2 9 10 20 21 rings
5 3 4 11 12 13 rings
21
2
0
2
0
0
0
0
1
1