493591
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
8
8
8
8
8
8
8
8
8
8
8
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
3
4
4
5
5
6
6
7
7
8
8
9
9
10
10
11
11
12
12
12
13
13
14
15
15
16
16
17
17
17
18
18
19
19
20
20
21
21
22
22
23
23
14
16
14
17
12
35
13
36
15
37
18
42
19
43
20
44
21
45
22
46
23
47
13
14
24
15
25
26
16
27
20
28
18
19
29
21
30
22
31
32
33
23
34
38
39
40
41
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
12
3
14
13
24
2
1
13
4
15
12
25
2
1
14
1
12
2
26
2
1
15
5
13
16
27
1
1
16
1
15
20
28
1
1
17
2
18
19
29
1
1
18
6
17
21
30
1
1
19
7
17
22
31
1
1
21
9
23
18
34
2
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
-1.6803
-0.0258
-0.9347
-3.7619
-4.4764
2.1309
0.1302
-2.4283
3.7222
1.4095
6.1207
-1.7362
-2.8419
-0.8688
-3.608
-2.6483
1.1989
2.3662
1.299
-3.3802
3.7447
1.361
4.9076
-2.195
-2.4372
-0.2498
-4.2379
-2.1206
1.2106
2.3743
2.1555
-4.1086
-3.8976
3.9409
-0.4764
-4.1305
-3.926
2.243
0.4657
4.977
4.8196
2.148
0.1238
-1.8458
4.5878
2.2105
6.2241
0.2613
-0.3376
-2.9921
-2.6532
0.108
-2.0166
2.3519
2.8835
-0.326
3.3819
-0.5532
-1.981
-1.5692
-0.7886
-0.3596
0.756
0.1949
-0.6471
1.6918
1.9064
-0.2147
1.9745
-1.0712
-2.4193
-1.3707
-1.1638
-0.6687
1.1659
0.1392
-0.6114
2.1595
2.3733
1.5717
0.8354
-2.5944
-2.8593
0.4185
1.5316
1.6033
-1.0644
-2.1057
-2.0956
2.2281
2.4789
-0.0286
3.7184
0.355
1.2718
-0.3171
-0.2663
-0.7831
-1.1254
-0.03
0.332
1.4036
1.6122
-1.8929
0.2271
0.3343
-0.6357
0.7414
-0.096
0.3393
0.1862
-0.3557
-0.1702
1.0251
0.1833
-1.6707
-0.313
1.2292
-1.6349
1.5667
0.747
-0.5317
1.283
-1.4501
0.3268
0.3558
1.9303
-0.056
-1.0264
0.0927
-1.8645
-2.1405
-2.1791
-1.4049
0.0326
0.9391
1.2964
2.0687
1.9409
-1.456
-0.1047
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0007881700000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
66.5625
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
106.693
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10756046 5 18191024710408788751
11315181 36 18410292523845872986
12553582 1 17967813825859353352
12788726 201 17986133970485693809
13009979 54 18338807804718747745
13140716 1 18267876149658976435
13583140 156 16702012063698564982
14178342 30 18413109433285470002
14181834 199 18115033029586444148
15420108 30 17835800798983030161
15442244 35 18410016554484420676
16945 1 18270409394315925243
17349148 13 18411979191113670630
17492 89 18192993952914732042
17980427 23 18201723950658653428
1813 80 17968106278819925932
18981168 100 15937551435794447469
192875 21 18341890822780878365
200 152 16988839479871740131
20600515 1 18338530659591272188
21267235 1 18412553123272379915
21501502 16 18265624349623718749
23402539 116 18201714042516585455
23419403 2 17979314790184511556
23557571 272 17632582621506913561
23558518 356 18189909784211991827
23559900 14 18129932481473478160
23598291 2 18334303105816853628
25147074 1 18266477549145883521
2748010 2 17471306054223860397
312423 11 18191319366793234763
34934 24 18188209776000253946
350125 39 18337117847289378993
6992083 37 18335427828744635181
7471813 234 18199178675554909780
74978 22 17969224597524266170
7615 1 18339657744455491921
81228 2 18190751834215086864
9981440 41 17325491497865821584
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
408.77
8.86
3.22
1.27
7.67
1.11
-0.14
-2.77
0.28
-1.6
-0.76
-0.08
0.82
-1.71
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
813.026
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
238.9
Conformer
RMSD
7
2009.12.11
1
Diverse Conformer
ID List
6
2012.02.08
1
17
19
12
44
56
43
45
47
30
54
24
32
58
5
22
57
38
49
3
53
21
20
10
28
46
33
39
26
8
36
15
52
4
2
23
34
51
16
37
40
31
41
13
35
18
27
55
42
6
29
11
7
25
9
50
14
48
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
32
1 -0.56
10 -0.68
11 -0.68
12 0.28
13 0.28
14 0.56
15 0.28
16 0.28
17 0.28
18 0.28
19 0.28
2 -0.56
20 0.28
21 0.28
22 0.28
23 0.28
3 -0.68
35 0.4
36 0.4
37 0.4
4 -0.68
42 0.4
43 0.4
44 0.4
45 0.4
46 0.4
47 0.4
5 -0.68
6 -0.68
7 -0.68
8 -0.68
9 -0.68
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
9.2
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
21
1 1 acceptor
1 10 acceptor
1 10 donor
1 11 acceptor
1 11 donor
1 2 acceptor
1 3 acceptor
1 3 donor
1 4 acceptor
1 4 donor
1 5 acceptor
1 5 donor
1 6 acceptor
1 6 donor
1 7 acceptor
1 7 donor
1 8 acceptor
1 8 donor
1 9 acceptor
1 9 donor
6 1 12 13 14 15 16 rings
23
9
9
0
0
0
0
0
1
1