4850050 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 16 9 9 9 8 8 8 8 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 4 7 8 8 9 9 9 10 10 11 11 11 12 12 13 14 14 14 15 15 15 16 16 17 17 18 19 20 20 20 21 21 21 22 22 23 24 24 25 25 26 26 27 27 28 28 29 29 30 30 32 32 34 34 35 36 36 36 5 6 10 13 33 33 33 23 31 36 12 14 15 22 44 18 23 51 13 17 16 20 37 38 21 39 40 18 41 19 42 19 43 45 46 47 48 49 50 25 26 24 27 30 28 52 29 53 32 33 31 54 31 55 34 56 35 57 35 58 59 60 61 62 2 2 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 2 1 1 1 2 1 1 2 1 2 1 2 1 1 1 1 1 1 1 2 1 1 1 1 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 3.0459 -5.073 -3.0623 -3.5031 2.1427 4.435 -1.7263 -1.918 4.5361 2.9786 -1.0166 3.1387 2.3472 5.4219 5.0976 0.9691 2.5522 0.3827 1.1744 5.6571 5.372 1.7182 -1.9701 -3.3505 1.6007 0.6135 -4.3305 0.3786 -0.6085 -3.6852 -0.726 -5.6452 -3.9995 -4.9998 -5.9797 -1.9682 6.385 5 4.4114 6.0253 0.3963 3.152 0.73 3.8045 6.3705 4.7364 6.0687 6.1277 4.4692 5.753 -1.358 2.4548 0.6825 0.3571 -1.464 -2.9351 -6.4245 -5.2607 -7.0032 -1.7728 -1.3058 -2.9902 -0.3612 -1.4654 -1.0153 -1.0697 -0.3274 0.0341 0.653 -3.7331 1.014 -1.9357 1.8695 1.2173 0.6405 1.9197 -0.1105 0.8564 2.0102 1.6493 2.2261 3.1675 0.2759 -2.3969 1.3825 1.7613 -2.7426 -2.4998 0.7969 -3.1912 -2.9485 3.1153 -3.2942 1.1865 -0.6601 3.5048 2.5405 -4.0697 1.4421 2.2327 -0.9635 -0.4541 0.401 2.4678 2.846 -2.2402 3.8224 3.7418 2.9413 1.0619 0.6184 -0.5919 2.452 -2.6651 -2.2706 -3.442 -3.0328 3.8798 0.4527 4.559 2.8442 -3.1972 -4.9099 -4.3981 1.8275 -0.2351 -0.9121 1.2166 2.9697 2.0135 1.476 -0.872 -0.4492 1.1342 -0.4007 -0.421 0.5724 0.2528 -1.169 0.5791 -1.4074 -0.4076 -1.4007 -0.5765 -2.6097 0.6176 0.5027 0.233 -0.7287 1.4631 -0.002 -1.2295 0.9624 0.2113 -0.3838 -0.2583 0.0141 -0.045 -0.2799 -2.2577 0.4671 1.2149 -1.1569 -0.6971 1.3709 -2.1894 -2.1752 0.6034 -0.0647 -0.7173 -1.5626 -2.6831 -3.1235 -3.1587 -1.1627 -1.3965 2.5215 -2.2844 1.6269 0.3975 -0.4439 -0.0605 -0.4792 -2.8904 -2.4921 -2.4734 Conformer ID 11 2.1 PubChem ncbi.nlm.nih.gov 2009.12.11 004A018200000001 Energy MMFF94 NoEstat 7 1.7.2 Szybki openeye.com 2012.11.26 122.6859 Feature Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 50.765 Fingerprint Shape 2 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 10483366 6 18123206619119155422 10675989 125 17905609896148334649 10906281 52 17823716186719954953 11093857 51 17841979002154094047 11513181 2 18273214162558671815 12422481 6 18195785415627421890 12788726 201 18049996998133630254 14117953 113 18049716322078768311 14289585 56 17530679905493629084 14294032 229 18200314446230976555 14790565 3 18409450262962118556 14840074 17 17894636932752212101 15001296 14 18190178073412425413 15297060 5 18202002127073899570 15392192 104 18339377262819260753 15575132 122 18410578405152866123 15664445 248 17691696588806607575 15968369 153 17977113683690031291 17492 54 17974035884994471118 18681886 176 18410014351272303520 20511986 3 18040981964848433633 22393880 68 18413111645161868485 23559900 14 17981323383506472029 244849 19 16988556979136155554 3052486 1 18335986484184506366 3298306 158 18413110533092087541 338550 245 18409725132352779551 3388396 114 17258491674241883389 38695281 34 18410860923411237869 513532 50 17631724963919692694 6287921 2 18128540353845618615 Shape Multipoles 8 1.8.3 OEShape openeye.com 2012.11.26 684.47 12.45 5.08 1.88 3.59 3.54 0.21 -11.54 -2.16 2.55 -1.81 -2.27 0.97 -1.51 Shape Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 1455.847 Shape Volume 7 1.8.3 OEShape openeye.com 2012.11.26 385.7 Conformer RMSD 7 2009.12.11 1.2 Diverse Conformer ID List 6 2012.02.08 1 14 28 12 40 35 9 30 8 19 15 34 32 38 18 6 25 31 22 11 33 23 13 16 3 39 7 17 37 21 36 2 24 27 26 29 10 5 20 4 Charge MMFF94 Partial 2 1.7.6 OEChem openeye.com 2012.02.08 47 1 1.45 10 -0.76 11 -0.55 12 0.1 13 -0.01 14 0.37 15 0.37 16 -0.15 17 -0.15 18 0.12 19 -0.15 2 -0.34 22 0.2 23 0.54 24 0.09 25 -0.15 26 -0.15 27 -0.14 28 -0.15 29 -0.15 3 -0.34 30 -0.15 31 0.08 32 -0.15 33 1.16 34 -0.15 35 -0.15 36 0.28 4 -0.34 41 0.15 42 0.15 43 0.15 44 0.42 5 -0.65 51 0.37 52 0.15 53 0.15 54 0.15 55 0.15 56 0.15 57 0.15 58 0.15 59 0.15 6 -0.65 7 -0.57 8 -0.36 9 -0.84 Count Effective Rotor 7 1.7.6 OEChem ncbi.nlm.nih.gov 2012.01.18 11 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.1 OEShape openeye.com 2012.02.08 10 1 10 donor 1 11 donor 1 5 acceptor 1 6 acceptor 1 7 acceptor 1 8 acceptor 1 9 cation 6 12 13 16 17 18 19 rings 6 22 25 26 28 29 31 rings 6 24 27 30 32 34 35 rings 36 0 0 0 0 0 0 0 1 2