4815184 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 16 8 8 8 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 4 5 5 5 6 6 7 7 7 8 8 8 10 10 10 11 11 11 13 14 14 14 15 15 16 16 16 17 17 18 18 18 20 20 21 9 14 12 19 22 9 10 12 9 13 19 22 36 22 37 38 16 23 24 12 13 15 17 18 19 25 20 26 27 28 29 21 30 31 32 33 21 34 35 1 1 2 2 2 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 14 1 18 19 25 3 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 1.6135 -2.0647 3.1752 2.4089 -0.3506 -0.4946 2.0092 1.2741 0.1097 0.3626 -2.2613 -1.5628 -1.6946 2.5375 -3.4661 -0.0643 -2.351 3.9207 2.6177 -4.1089 -3.5521 1.9421 0.1513 1.4439 2.0142 -3.9163 0.1357 -1.137 0.4738 -1.9284 4.4913 3.8601 4.5023 -5.0437 -4.0526 1.5747 0.8939 1.1425 1.7269 1.5753 0.2639 -1.9932 1.6261 0.2052 -1.6003 -3.539 1.122 2.6684 0.1246 1.1745 -0.3189 0.1794 -0.4162 4.0538 -1.3158 0.4218 -0.3504 -1.4087 -1.8587 -2.3405 2.5548 2.5531 -0.5286 -0.0799 4.223 4.2047 4.8162 -1.6761 -0.5139 0.793 1.1365 -1.8314 -2.6319 -2.0183 -3.8064 -4.1887 -1.4875 2.0202 0.8069 2.3026 0.422 -1.4891 0.0351 1.0367 -0.8016 1.1658 0.2022 0.9733 -0.9942 -1.5249 0.6665 0.7268 -1.7255 -2.115 -0.1002 -0.0721 -1.267 1.2194 2.2355 1.0556 -2.1762 1.5963 -0.3356 0.8877 1.2988 -2.6605 -2.1334 -3.144 -1.5211 0.2845 -1.8426 -0.7829 0.1351 1.8048 Conformer ID 11 2.1 PubChem ncbi.nlm.nih.gov 2009.12.11 0049795000000003 Energy MMFF94 NoEstat 7 1.6.0 Szybki openeye.com 2012.01.18 51.3401 Feature Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.01.18 40.678 Fingerprint Shape 2 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 11578080 2 18265029427670807797 11582403 64 11190833964662797316 12553582 1 18343585161609385495 12788726 201 18267313027748893249 128993 33 11742684760645424266 13149001 5 17831599921551115492 13583140 156 18190485881730446769 13911987 19 16880225405407250556 14787075 74 18126564754941674956 15375462 189 18411135874638645847 16752209 62 18059860524189598493 16945 1 18040441017922149476 18981168 100 14548147936695384298 20567600 347 17049064387522113877 20600515 1 17632007654066043511 21033648 29 16271929277384940123 21731516 1 18341885286314813055 22112679 90 18271252633566057985 2255824 54 18053382385998670421 23419403 2 16598646988266412576 23559900 14 17274834557479334541 23598294 1 18058745588833225717 238 59 17822857622524719659 2748010 2 17126249747900670821 35225 105 17485924129796904633 3759504 43 16826700302825403641 392239 28 18126259030621472266 Shape Multipoles 8 1.8.1 OEShape openeye.com 2012.01.18 419.07 6.12 3.57 2.07 2.13 1.17 -0.04 -3.09 1.83 -1.17 -2.28 -0.97 -0.46 -1.93 Shape Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.01.18 870.268 Shape Volume 7 1.8.1 OEShape openeye.com 2012.01.18 240.5 Conformer RMSD 7 2009.12.11 0.8 Diverse Conformer ID List 6 2012.02.08 3 55 38 68 66 30 27 47 60 75 74 70 71 5 59 42 77 52 26 64 58 81 16 49 35 8 50 41 6 19 22 48 37 40 18 14 10 54 69 65 57 11 56 53 31 2 25 45 1 73 32 15 17 9 28 4 61 63 51 23 80 76 46 44 34 67 29 13 78 72 79 39 24 43 36 7 12 33 62 20 21 Charge MMFF94 Partial 2 1.7.6 OEChem openeye.com 2012.02.08 27 1 -0.37 10 0.3 11 0.09 12 0.54 13 0.18 14 0.29 15 -0.15 17 -0.15 19 0.57 2 -0.57 20 -0.15 21 -0.15 22 0.69 26 0.15 3 -0.57 30 0.15 34 0.15 35 0.15 36 0.37 37 0.37 38 0.37 4 -0.57 5 -0.42 6 -0.63 7 -0.49 8 -0.8 9 0.65 Count Effective Rotor 7 1.7.6 OEChem ncbi.nlm.nih.gov 2012.01.18 6 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.1 OEShape openeye.com 2012.02.08 8 1 18 hydrophobe 1 2 acceptor 1 3 acceptor 1 4 acceptor 1 7 donor 1 8 donor 6 11 13 15 17 20 21 rings 6 5 6 9 11 12 13 rings 22 1 0 1 0 0 0 0 1 5