4794449 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 16 8 8 8 8 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 4 5 6 6 6 7 7 7 8 8 8 9 9 9 10 10 10 11 11 16 16 16 18 18 19 20 20 20 21 21 21 22 22 23 23 24 24 24 25 25 26 10 18 13 14 15 17 12 16 17 12 13 27 15 17 21 14 19 30 11 13 14 12 15 20 28 29 19 22 23 24 31 32 33 34 35 25 36 26 37 38 39 40 26 41 42 1 1 2 2 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 10 1 11 13 14 3 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 1.4849 1.2487 0.7182 -0.4564 -4.8196 -3.0208 -0.9852 -2.6609 2.7282 0.6454 -0.7861 -1.6585 0.3938 1.3536 -1.26 -3.8768 -3.5994 3.1594 3.5937 -4.1879 -3.2257 4.0827 4.946 -5.0977 5.424 5.8564 -1.4295 -4.8209 -3.436 3.1641 -4.6619 -3.2561 -2.4551 -3.8508 -3.8612 3.7718 5.3009 -6.0571 -5.2942 -4.6349 6.1315 6.9015 0.0606 -2.2452 1.4361 2.732 1.0713 -0.3333 -1.6121 1.9373 0.7758 0.0425 0.4902 -0.4808 -1.4166 0.8373 1.8292 -1.4738 0.8976 -0.1864 0.2083 -2.3215 3.226 -0.7232 0.0802 -3.5005 -0.8681 -0.4632 -2.4893 -1.0895 -2.0754 1.1841 -1.7001 -2.6994 3.9665 3.5933 3.0847 -1.0291 0.3951 -3.1577 -4.0808 -4.1648 -1.2872 -0.567 -1.4037 0.8917 2.1587 -0.5812 -0.2353 0.2163 0.6338 -0.4359 1.3462 0.1947 0.0233 0.2887 0.6131 1.2845 -0.3617 0.5302 -0.1564 -0.8719 0.3952 -0.6976 -0.8209 -1.7795 0.7401 -0.3832 -1.4239 -0.165 0.8736 0.9367 1.333 2.1692 -1.4672 -1.135 -1.0474 -0.0007 -1.7009 -2.7762 1.7187 0.0169 -1.2901 0.3534 -2.1333 0.1112 Conformer ID 11 2.1 PubChem ncbi.nlm.nih.gov 2009.12.11 0049285100000003 Energy MMFF94 NoEstat 7 1.7.2 Szybki openeye.com 2012.11.26 62.0812 Feature Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 55.93 Fingerprint Shape 2 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 10411042 1 18192150610933127803 10498660 4 18189332377335913564 11796584 16 18268431227201425854 121448 382 18334021561883367467 12166972 35 17386847386548599727 12236239 1 17022906718166253276 12293681 4 17560529404288781961 12390115 104 18124882253212327913 12403259 226 18270112543224497657 12403260 363 18259984898850591628 12553582 1 18188492497140290987 12623949 98 17486502778019921287 13140716 1 18263086668819694361 13583140 156 17988920054965742950 13782708 43 18059575835971377390 14294032 229 17969216738726379285 14790565 3 17691692177759721537 16087824 20 18335698301471264333 16752209 62 18186521020713828914 17349148 13 17749112205229466494 20775438 99 17186708962886687335 21033650 10 18118430387503920558 21065201 7 18411695470137966250 21267235 1 18335987571212184731 22393880 68 18412820270274932415 23175994 123 17704354351206863808 23366157 5 17244140423617526906 23402539 116 18334294275205961038 23557571 272 18341897385110909959 23559900 14 18413105061156397124 3286 77 17631457919774425947 474 4 16298682598554036388 59755656 215 18409162221429234063 7495541 125 17917150606189026938 Shape Multipoles 8 1.8.3 OEShape openeye.com 2012.11.26 495.52 11.24 2.9 1.38 4.74 0.06 0.07 -5.16 -2.79 -5.61 -0.52 1.33 0.12 0.88 Shape Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 1080.473 Shape Volume 7 1.8.3 OEShape openeye.com 2012.11.26 270.7 Conformer RMSD 7 2009.12.11 0.6 Diverse Conformer ID List 6 2010.05.05 3 8 2 5 1 7 6 4 Charge MMFF94 Partial 2 1.7.6 OEChem openeye.com 2012.05.21 30 1 -0.33 10 0.49 11 -0.12 12 0.22 13 0.57 14 0.57 15 0.62 16 0.3 17 0.69 18 0.1 19 0.12 2 -0.57 21 0.3 22 -0.15 23 -0.15 25 -0.15 26 -0.15 27 0.37 3 -0.57 30 0.37 36 0.15 37 0.15 4 -0.57 41 0.15 42 0.15 5 -0.57 6 -0.47 7 -0.54 8 -0.42 9 -0.55 Count Effective Rotor 7 1.7.6 OEChem ncbi.nlm.nih.gov 2012.01.18 2.6 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.1 OEShape openeye.com 2012.05.21 11 1 2 acceptor 1 24 hydrophobe 1 3 acceptor 1 4 acceptor 1 5 acceptor 1 7 donor 1 9 donor 5 7 10 11 12 13 rings 6 1 9 10 14 18 19 rings 6 18 19 22 23 25 26 rings 6 6 8 11 12 15 17 rings 26 1 0 1 0 0 0 0 1 8