4781
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
8
8
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
3
3
3
4
4
5
5
5
5
6
6
6
9
9
9
10
10
10
11
11
12
12
13
13
13
14
14
15
15
16
16
17
17
18
18
19
19
20
20
21
21
22
23
7
8
4
7
11
8
12
6
7
8
24
9
25
26
10
27
28
13
29
30
14
16
15
17
31
32
33
18
34
19
35
20
36
21
37
22
38
23
39
22
40
23
41
42
43
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
2
1
1
1
1
1
1
1
1
2
1
2
1
2
1
2
1
1
1
1
1
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
0.4591
2.0818
-0.3558
0.186
1.6509
3.0072
0.541
1.3514
3.1113
4.4899
-1.7422
-0.1218
4.6091
-2.1592
0.3172
-2.6863
-0.8627
-3.5135
0.017
-4.0406
-1.1628
-4.4542
-0.7229
1.5944
3.1831
3.7953
2.3499
2.9408
4.6736
5.2674
4.4647
3.8644
5.6018
-1.469
0.8507
-2.4314
-1.1572
-3.8354
0.3499
-4.7755
-1.723
-5.5089
-0.9552
-3.0951
0.8807
-0.8608
0.3512
-1.3669
-1.5889
-1.9201
0.1041
-0.8724
-1.0704
-1.071
1.6419
-0.3314
-2.2241
2.7923
-0.1248
1.7594
-2.4299
4.053
-0.3308
3.0203
-1.4833
4.167
-1.8441
-2.6622
-1.2204
-1.246
0.2036
-2.1384
-0.7088
0.745
-0.6897
-0.4882
-2.9677
2.7654
0.7469
0.9058
-3.322
4.9467
0.3972
3.1097
-1.6443
5.1487
0.1715
2.1247
0.2923
0.7852
1.3601
0.7154
0.4974
1.527
-0.6307
-1.2606
0.0232
0.2572
-2.5839
-0.6455
0.9169
0.4281
-0.9212
-0.9083
0.4011
0.1654
-1.4368
-0.5028
-0.7756
2.3446
0.5731
1.3838
-1.3254
-0.5124
-1.4259
-0.5776
-2.4469
-3.3017
-3.0174
-1.0261
1.8596
1.0213
-1.5221
-1.4377
0.921
0.4966
-2.3631
-0.7058
-1.1781
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
000012AD00000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
78.2418
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
35.522
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10369192 42 17201337802391171616
104564 63 18263924341411838103
10764073 3 13897455744096634170
10871710 139 18116739347057634380
12035759 4 18114472162491707708
12054548 360 18410852140123729741
12553582 1 18408597059472287483
12788726 201 18263089837924985030
13140716 1 18194372564396360809
13149001 5 17900835043207325562
14347332 77 18267594498837176158
14363568 33 18189911975009627505
14790565 3 17836088870977357177
14910302 57 17772489906022800270
14955137 171 18194712399700016531
15210252 30 18113619023062467228
15475509 8 18129964294665595431
16945 1 18052516803837800083
17357779 13 18196061448885290669
17980427 26 15408333429898477840
1813 80 18340767130181322479
20600515 1 18197199537524542050
20691752 17 18334851757544844714
21285901 2 17987812795090682943
21330990 113 17559693753581092550
22182313 1 18056732404992144296
22907989 373 18192711137738959261
23557571 272 18340478990042856330
23558518 356 17756145583554754635
23559900 14 18057883744017265111
23566358 27 17906183102573167091
2748010 2 18124842786050261944
352729 6 17331105101814950347
4409770 3 17977362963866204091
532947 4 18050010183794161276
57262259 84 18129112129998427340
59444896 2 17618840942390023921
6287921 2 17839454828108877135
7164475 11 18264488382698967990
7364860 26 18051968418482417633
81228 2 18044080264456652201
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
451.63
6.73
4.66
1.68
1.86
5.6
-0.29
-5.85
-3.83
-1.87
-0.66
1.98
0.21
0.05
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
968.582
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
248.3
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.02.08
1
6
17
18
2
5
16
7
8
3
14
10
4
9
13
15
12
11
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
29
1 -0.57
11 0.12
12 0.12
14 -0.15
15 -0.15
16 -0.15
17 -0.15
18 -0.15
19 -0.15
2 -0.57
20 -0.15
21 -0.15
22 -0.15
23 -0.15
3 -0.18
34 0.15
35 0.15
36 0.15
37 0.15
38 0.15
39 0.15
4 -0.18
40 0.15
41 0.15
42 0.15
43 0.15
5 0.12
7 0.57
8 0.57
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
5.6
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
7
1 1 acceptor
1 13 hydrophobe
1 2 acceptor
1 5 anion
5 3 4 5 7 8 rings
6 11 14 16 18 20 22 rings
6 12 15 17 19 21 23 rings
23
0
0
0
0
0
0
0
1
2