46882313 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 16 16 16 16 16 16 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 3 4 5 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 21 22 23 24 25 26 27 28 28 29 30 31 32 33 34 35 36 37 37 38 39 40 41 42 42 43 44 45 45 46 46 47 48 48 49 50 51 52 53 53 53 54 54 54 55 55 55 56 56 56 57 57 57 58 58 58 59 59 59 60 60 60 61 61 61 62 62 62 63 63 63 64 64 64 65 65 65 66 66 66 67 67 67 68 68 68 69 69 69 70 70 70 71 71 71 72 72 72 73 73 73 74 74 74 75 75 75 76 76 76 77 77 77 78 78 78 79 79 79 80 80 80 81 81 81 82 82 82 83 83 83 84 84 85 85 85 86 86 86 87 87 87 88 88 88 89 89 89 90 90 90 91 91 91 92 92 92 93 93 93 94 94 94 95 95 96 96 96 97 97 98 98 98 99 99 100 100 100 101 101 101 102 102 102 103 103 103 104 104 106 107 107 108 108 108 109 109 109 110 110 110 111 111 111 112 112 112 113 113 114 114 116 116 116 117 117 117 118 118 118 119 120 120 121 123 123 123 124 124 125 125 125 126 126 126 128 128 128 129 129 130 130 130 131 131 132 132 132 133 133 133 134 134 134 135 135 135 136 136 136 137 137 137 139 140 141 141 141 142 142 143 143 144 144 144 146 146 146 147 147 147 148 148 149 149 149 150 150 150 151 151 151 152 153 153 153 156 156 156 157 157 157 158 158 158 159 159 159 160 160 160 161 162 162 162 164 164 164 165 165 165 167 167 169 169 170 170 170 171 172 172 174 174 174 175 175 175 176 176 177 177 177 178 178 180 180 182 182 183 184 184 185 186 186 186 188 188 189 189 189 190 190 190 191 191 191 193 193 193 194 194 194 197 197 197 198 198 198 199 199 199 200 201 201 201 202 202 203 203 203 204 204 205 205 206 206 206 210 210 210 211 212 212 213 213 214 214 215 215 216 216 217 217 217 218 220 220 220 221 221 222 222 223 223 225 225 227 227 227 231 231 233 233 233 235 235 235 2 113 141 4 131 162 6 180 182 105 106 115 119 121 122 127 138 139 140 145 152 154 155 166 362 161 163 166 168 171 173 176 377 179 181 183 185 187 192 196 200 207 426 207 208 209 211 219 441 218 219 224 444 225 446 228 231 449 229 230 236 237 101 104 106 105 108 247 109 114 121 107 119 259 115 117 264 122 136 277 120 140 279 127 130 282 124 139 289 129 300 301 138 144 305 142 155 319 145 150 320 143 161 322 154 156 327 148 171 330 163 174 345 168 177 349 167 183 355 169 185 359 172 195 363 173 367 368 181 186 370 178 200 372 179 197 373 184 196 380 187 194 381 190 192 385 188 211 392 195 404 405 202 218 408 195 409 209 217 414 208 220 415 205 226 418 212 232 420 213 234 427 216 230 428 223 236 434 227 229 435 228 235 436 226 442 443 226 445 232 447 448 232 450 234 451 452 234 453 237 454 455 102 105 238 103 239 240 104 241 242 243 244 107 113 245 110 115 246 111 122 248 116 249 250 112 251 252 114 253 254 255 256 257 258 123 260 261 118 127 262 126 128 263 120 125 265 124 129 266 267 131 268 132 133 269 135 270 271 272 273 274 275 276 134 138 278 280 281 283 284 285 286 287 288 137 290 291 292 293 294 145 295 296 146 147 297 143 148 142 298 299 154 302 151 303 149 152 304 306 307 308 309 310 311 312 313 159 314 315 155 160 316 166 317 318 153 157 163 321 158 168 323 164 324 325 165 170 326 173 328 329 331 332 333 167 169 334 335 172 336 337 175 338 339 176 340 179 341 342 343 344 178 346 347 180 181 348 350 351 352 353 354 182 187 356 357 358 360 361 364 365 184 191 366 188 189 192 369 193 371 199 374 375 196 198 376 207 378 379 204 382 383 201 208 384 209 386 387 203 388 389 205 390 391 202 206 393 394 210 395 212 396 397 214 215 398 399 213 400 401 219 402 403 216 406 407 410 411 221 412 222 413 416 417 225 228 419 223 229 421 422 224 423 224 424 231 425 429 430 230 233 431 432 433 237 437 438 236 439 440 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 2 2 1 1 2 2 2 2 2 2 1 1 2 2 2 2 2 2 2 2 1 1 2 2 2 2 1 1 2 2 1 1 1 1 2 1 1 2 2 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 2 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 101 53 102 105 238 1 1 107 56 113 106 245 2 1 108 54 110 115 246 1 1 109 55 111 122 248 1 1 117 57 118 127 262 1 1 118 117 128 126 263 2 1 120 59 125 119 265 2 1 124 61 131 121 268 2 1 130 60 134 138 278 1 1 142 64 141 154 302 1 1 143 66 151 139 303 2 1 144 63 149 152 304 1 1 150 65 160 155 316 2 1 153 152 163 157 321 2 1 156 67 158 168 323 1 1 158 156 170 165 326 2 1 167 71 176 161 340 2 1 169 72 162 179 341 1 1 174 69 180 181 348 1 1 177 70 182 187 356 1 1 184 78 191 183 366 2 1 186 75 189 192 369 1 1 188 81 193 185 371 2 1 190 80 198 196 376 2 1 194 79 201 208 384 1 1 202 83 210 200 395 2 1 217 85 225 228 419 1 1 223 91 231 218 425 2 1 227 92 233 230 431 2 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 5.602 6.0338 6.9764 6.9113 9.5271 10.3775 6.5804 4.7204 7.0137 4.6346 6.1826 2.4766 7.4248 7.7931 7.8855 4.6463 2.1576 8.1 8.5667 5.5543 7.3215 8.1724 8.2628 9.0528 12.0003 4.7549 8.3069 8.6045 6.847 8.435 8.3789 8.8277 10.3371 8.5136 8.4946 4.9549 9.9338 8.3972 12.041 6.411 10.1452 3.6323 5.2362 3.8429 10.353 5.5318 5.9831 4.5734 8.4159 6.6486 5.5848 8.3682 5.6968 6.6473 5.0175 5.6396 6.8554 2.8494 5.6294 7.0493 7.1567 4.5329 7.2193 6.6615 3.6841 7.3077 9.5805 5.6667 7.4268 11.675 7.4218 7.302 9.8443 9.4786 7.4957 5.7495 6.6357 7.4931 11.5532 7.5182 8.4866 11.5722 5.8737 10.6041 6.4239 10.5278 9.582 10.3405 10.9165 7.9102 6.0331 8.0189 6.2196 11.302 10.6188 12.0443 11.462 12.6478 11.828 10.0995 6.5058 6.1968 5.1968 4.8877 6.5765 5.6726 5.6536 6.7176 4.0499 6.8707 3.4057 3.9021 5.4709 4.8735 6.7871 6.0914 6.9221 7.2916 5.631 5.6275 6.0781 3.2959 6.2445 7.0995 4.6644 6.6716 6.9869 8.2811 5.4653 7.1091 7.0392 4.4159 3.9498 7.6763 7.041 2.7661 7.2467 7.1658 7.2107 5.6366 6.724 7.6046 7.2612 7.2691 3.0564 7.814 6.2499 5.6491 8.0056 4.5709 8.1419 7.315 7.3567 8.589 5.6064 10.4814 8.1859 11.2453 7.788 3.9509 7.3502 6.8443 7.3941 9.0846 11.0683 8.1721 7.3882 11.2033 6.7758 12.1861 5.6894 9.9138 8.5245 7.4548 11.8321 8.3524 11.8503 5.7171 6.7061 8.4543 7.4778 11.377 7.4505 7.4743 8.3015 7.5084 11.3241 8.7748 8.4274 7.5151 8.4734 7.5159 9.71 10.8249 10.6735 7.5067 6.5649 8.4569 8.5452 5.7866 9.9745 5.8281 9.2189 9.8707 9.4641 10.0051 8.9348 11.054 6.4942 5.2265 9.1718 10.1607 10.886 9.0963 10.8059 8.8836 6.3545 5.9233 4.2339 9.6775 9.2571 10.9666 5.9765 10.1922 6.3831 10.5009 8.3071 6.2862 8.7041 7.622 5.5681 11.2823 9.188 11.7974 6.155 6.0927 9.2186 7.1934 6.1319 6.8032 4.5903 5.2616 4.5777 4.3213 4.827 6.3422 6.6961 3.867 7.1694 7.4576 2.9075 2.9832 4.0863 3.3344 4.96 6.0907 5.4932 4.9217 5.0276 5.7927 5.5045 6.5711 7.676 7.0407 5.027 6.5433 6.8314 7.573 5.1075 6.2592 6.144 8.1914 8.8945 8.3707 5.1442 5.9318 2.2495 6.9853 5.0107 7.5777 6.7333 7.3618 3.8153 4.2618 5.0164 4.3836 3.5068 3.5161 7.5397 8.1814 8.1181 6.4649 7.2701 7.6172 2.2172 3.383 7.8648 6.14 7.1003 4.438 4.0498 7.8859 7.5872 7.2838 7.6432 7.3034 8.1657 8.3246 6.2006 5.6318 6.2992 5.1955 6.2549 8.5781 8.3393 4.4812 8.3362 8.7554 6.8464 3.2561 7.4638 7.7897 10.7694 7.7554 8.5505 11.355 9.7593 7.2155 7.4543 5.0724 3.4644 3.5664 4.4373 7.3007 6.6662 9.5151 8.72 10.4864 10.7564 7.8236 7.5647 12.3962 12.7695 11.9761 7.9869 10.5154 10.1658 8.2477 12.2609 11.432 12.3057 12.2323 8.4107 8.9704 7.9785 12.6896 5.3691 6.2783 7.0085 8.208 8.3384 7.3402 9.2872 11.9658 11.288 7.9971 9.6134 9.9352 8.1241 8.1009 9.3867 5.2095 6.6769 9.0464 8.5693 8.125 9.2023 8.3926 9.0647 8.0966 12.1469 9.8256 10.3299 10.2052 8.1381 6.8771 6.5701 8.9343 8.1502 7.9262 8.4033 7.8831 9.3675 9.7448 5.2574 8.7415 9.5256 10.0831 9.606 9.8109 9.3915 5.779 5.0454 12.0863 11.6153 10.2646 10.7807 5.4152 11.1182 11.0801 11.4996 8.5166 11.286 6.3262 10.6699 8.9187 9.4993 9.0853 6.06 9.868 10.1291 9.384 8.777 11.5464 5.4743 10.2199 10.3893 7.4854 6.9904 6.6118 8.9268 6.1694 5.5237 5.6791 7.4154 5.988 9.3822 9.8016 6.2035 6.429 3.0169 11.8717 11.2289 10.9328 11.1885 5.5496 12.6282 11.9328 4.3202 12.0459 13.1939 12.6288 11.3008 10.6267 10.1184 1.7182 2.6208 -1.3328 -1.3606 -0.5688 -0.0426 1.4674 0.116 1.4168 -0.3117 -2.5536 -0.8644 1.2709 1.0371 -1.9136 -0.7478 3.1959 0.7271 4.9989 5.4431 -3.125 -1.585 0.4856 -3.0727 3.3403 -1.1703 3.4665 -2.1894 -2.4039 0.0848 -1.2007 -3.0714 1.5585 -0.3443 -0.7801 -1.558 -1.7376 -2.5368 4.5119 -2.4165 0.1166 -2.5362 -1.8914 -0.817 -5.6424 -2.9219 -2.3317 -2.227 5.862 2.7193 -2.1537 1.2194 -0.1228 0.4645 -1.4818 -0.3269 0.4242 0.6742 -0.5387 0.3385 -1.2214 3.3246 0.2118 4.3115 3.6157 -1.0726 3.8644 -0.7474 -0.0725 1.854 -0.8939 -2.2516 1.7273 2.1909 -0.273 -0.9425 -1.4212 -0.6942 2.6926 -0.4837 -0.3826 1.8476 -1.1143 3.2838 -1.4115 5.2015 2.4324 -1.563 0.3792 1.5326 -1.2541 4.1761 -1.3548 2.2282 3.8198 -1.2516 -2.8829 0.4321 -1.0936 1.2724 0.465 1.4161 1.4161 0.465 0.4674 -0.1893 -0.2575 0.4563 -1.0407 1.4445 -1.7914 -2.647 0.7263 -2.4604 0.4428 2.0712 0.4005 1.3298 -0.3972 -0.4679 -1.5591 -0.2909 3.0594 -1.263 -0.1988 2.1144 0.3719 1.4744 3.6861 0.3006 -1.3002 0.7698 -0.8984 1.1242 3.0436 1.7343 2.0272 0.2583 -1.1756 -0.6091 3.3452 3.8202 -1.1259 0.1615 2.7574 2.8507 2.1066 -0.6788 0.838 4.2025 -1.5996 0.1076 0.0505 3.9992 4.4444 3.4292 0.6094 4.0746 1.814 4.987 -1.0159 -1.3835 -0.0097 0.1707 5.0588 -2.5991 -0.9562 2.7364 -1.4012 3.7358 -0.8144 0.7297 2.4905 -0.1375 5.7042 -1.2217 0.8689 -0.8796 -1.4138 -0.107 -0.2045 -0.012 -0.8292 -0.7625 -2.221 -0.3426 1.7192 -1.3401 0.0519 -0.5545 -0.8065 -0.413 -1.6944 3.3778 2.2862 -0.6248 -1.4232 -0.8906 1.0449 -1.0028 2.8516 -1.0602 -0.2431 -2.6814 1.4393 1.852 -1.6936 4.3512 -1.42 -1.859 0.3458 -0.5793 1.3787 -3.3141 -3.0357 1.3034 -1.3977 -1.1648 -1.7374 4.6753 -4.3011 -4.0227 -1.2115 -4.6554 -2.3973 2.8268 3.2185 -1.3788 4.9045 2.4901 -2.1243 -1.8992 2.7452 -0.0941 -1.3259 -1.2923 1.7457 0.9646 2.0327 1.545 1.545 2.0327 -0.0719 0.7172 -0.0593 0.9497 1.0825 -0.2106 1.9877 1.2446 -2.1605 -1.3376 -3.239 -2.8963 0.3751 0.7424 -2.4816 -3.0786 -0.2279 1.5279 2.271 1.1747 0.8433 1.0158 -0.622 3.6026 2.8595 -1.9689 0.2349 1.6513 2.44 2.0879 1.5641 0.8609 4.2164 4.0944 0.5173 0.9081 -0.5785 -1.6076 -0.7609 0.874 0.6157 1.3704 0.9239 -1.3414 -1.3321 -0.4553 -1.709 1.4837 0.6891 3.2727 3.6197 2.8145 1.446 1.673 1.9779 3.5534 2.8524 2.7119 3.7131 3.0181 -1.6532 0.7814 0.6642 3.2024 3.3613 2.499 1.4886 2.1559 2.7247 -1.1015 -0.5471 1.0759 0.3155 4.8159 -1.0108 -1.6887 4.9033 4.0643 0.6611 -1.4626 4.2289 1.0555 1.1109 3.4644 4.4581 1.5761 2.3365 -0.924 4.6026 5.4734 5.3714 -1.8031 -0.7896 -0.2754 -0.3307 4.8448 5.5947 -1.3977 -1.7176 4.3191 3.5257 3.1525 0.1935 0.8795 0.1632 0.1686 2.057 6.1778 6.1044 5.2306 -0.6045 -1.1719 -1.1667 0.7347 -1.3927 -0.6162 -2.7977 0.462 -0.716 -3.7447 1.9992 -0.2062 -0.6256 -1.0958 1.5857 2.6102 -0.4157 -0.1385 -1.2405 -1.2472 -2.0398 0.0868 -0.5517 -0.443 -2.354 -0.1917 -0.6202 -0.8361 2.8713 -1.0853 -1.7025 3.3588 -0.4876 -1.9589 -0.8033 -1.2862 -1.4295 1.0099 1.6484 -0.2405 2.7253 3.4274 -1.3026 0.1525 0.2957 1.4743 0.8358 1.2632 1.941 -2.1403 -2.452 2.1941 1.2291 0.032 -0.5754 -1.5316 3.6303 1.9675 1.2898 -3.0945 -2.6434 -2.0237 5.805 1.9224 1.3763 2.8035 -1.9433 -1.9645 4.2505 4.1291 -4.6934 -4.2423 -1.575 -2.2876 0.0529 1.081 -2.2722 -2.9736 3.2375 -2.2754 -2.7427 -1.7631 4.3182 -1.9299 3.334 2.6563 -1.944 -0.7698 -2.4609 2.4728 1.6126 -5.862 4.0644 -3.5417 -1.4601 -0.6417 -2.7929 -3.0913 0.1387 1.0518 -1.4199 1.5986 0.6527 6 6 5 6 6 6 5 6 5 5 5 5 5 6 6 6 5 5 6 6 5 5 5 5 5 5 8 8 8 8 5 8 8 5 5 101 107 108 109 117 118 120 124 130 142 143 144 150 153 156 158 167 169 174 177 184 186 188 190 194 202 204 204 214 215 217 221 222 223 227 238 245 110 248 262 128 125 268 134 302 151 149 160 157 323 170 176 341 348 356 191 189 193 198 201 210 214 215 221 222 225 224 224 231 233 0 Compound Canonicalized 5 2019.01.04 1 Compound Complexity 7 E_COMPLEXITY 3.4.8.18 Cactvs Xemistry GmbH 2021.05.07 8230 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.4.8.18 Cactvs Xemistry GmbH 2021.05.07 57 Count Hydrogen Bond Donor 5 E_NHDONORS 3.4.8.18 Cactvs Xemistry GmbH 2021.05.07 53 Count Rotatable Bond 5 E_NROTBONDS 3.4.8.18 Cactvs Xemistry GmbH 2021.05.07 47 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.4.8.18 Cactvs Xemistry GmbH 2021.05.07 00000371F07FFE00700000000000000000000000000162C00000300000000000000000010000001E04100800000D2CE5D806B30E83C00200A802A1D23800020000A020000988818E08888A763E8AD93394700026F613989807BFCBE0AE20000000000000004000000000000000000000000000 IUPAC Name Allowed 1 2.7.0 Lexichem TK OpenEye Scientific Software 2021.05.07 2-[(1R,5aS,7S,10S,13S,16S,19S,21S,24R,27S,30S,33S,36S,39S,42R,48S,54S,57R,60S,63R,66S,72S,78S,81R,87S,93S,96S)-10-(4-aminobutyl)-72-(2-amino-2-oxo-ethyl)-19-(3-amino-3-oxo-propyl)-39,96-bis(carboxymethyl)-21,27,30,66-tetrakis(3-guanidinopropyl)-36,87,93-tris(hydroxymethyl)-78-[(4-hydroxyphenyl)methyl]-16-isobutyl-5a-isopropyl-54-methyl-13,60-bis[(1S)-1-methylpropyl]-a,2,3a,6a,8,11,14,17,20,22,25,28,31,34,37,40,43,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,97-tetratriacontaoxo-9a,10a,13a,14a,17a,18a-hexathia-1a,3,4a,7a,9,12,15,18,23,26,29,32,35,38,41,44,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tritriacontazahexacyclo[55.50.4.424,63.442,81.03,7.044,48]nonadecahectan-33-yl]acetic acid IUPAC Name CAS-like Style 1 2.7.0 Lexichem TK OpenEye Scientific Software 2021.05.07 2-[(1R,5aS,7S,10S,13S,16S,19S,21S,24R,27S,30S,33S,36S,39S,42R,48S,54S,57R,60S,63R,66S,72S,78S,81R,87S,93S,96S)-10-(4-aminobutyl)-72-(2-amino-2-oxoethyl)-19-(3-amino-3-oxopropyl)-13,60-bis[(2S)-butan-2-yl]-21,27,30,66-tetrakis(3-carbamimidamidopropyl)-39,96-bis(carboxymethyl)-36,87,93-tris(hydroxymethyl)-78-[(4-hydroxyphenyl)methyl]-54-methyl-16-(2-methylpropyl)-a,2,3a,6a,8,11,14,17,20,22,25,28,31,34,37,40,43,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,97-tetratriacontaoxo-5a-propan-2-yl-9a,10a,13a,14a,17a,18a-hexathia-1a,3,4a,7a,9,12,15,18,23,26,29,32,35,38,41,44,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tritriacontazahexacyclo[55.50.4.424,63.442,81.03,7.044,48]nonadecahectan-33-yl]acetic acid IUPAC Name Markup 1 2.7.0 Lexichem TK OpenEye Scientific Software 2021.05.07 2-[(1<I>R</I>,5<I>a</I><I>S</I>,7<I>S</I>,10<I>S</I>,13<I>S</I>,16<I>S</I>,19<I>S</I>,21<I>S</I>,24<I>R</I>,27<I>S</I>,30<I>S</I>,33<I>S</I>,36<I>S</I>,39<I>S</I>,42<I>R</I>,48<I>S</I>,54<I>S</I>,57<I>R</I>,60<I>S</I>,63<I>R</I>,66<I>S</I>,72<I>S</I>,78<I>S</I>,81<I>R</I>,87<I>S</I>,93<I>S</I>,96<I>S</I>)-10-(4-aminobutyl)-72-(2-amino-2-oxoethyl)-19-(3-amino-3-oxopropyl)-13,60-bis[(2<I>S</I>)-butan-2-yl]-21,27,30,66-tetrakis(3-carbamimidamidopropyl)-39,96-bis(carboxymethyl)-36,87,93-tris(hydroxymethyl)-78-[(4-hydroxyphenyl)methyl]-54-methyl-16-(2-methylpropyl)-<I>a</I>,2,3<I>a</I>,6<I>a</I>,8,11,14,17,20,22,25,28,31,34,37,40,43,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,97-tetratriacontaoxo-5<I>a</I>-propan-2-yl-9<I>a</I>,10<I>a</I>,13<I>a</I>,14<I>a</I>,17<I>a</I>,18<I>a</I>-hexathia-1<I>a</I>,3,4<I>a</I>,7<I>a</I>,9,12,15,18,23,26,29,32,35,38,41,44,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tritriacontazahexacyclo[55.50.4.4<SUP>24,63</SUP>.4<SUP>42,81</SUP>.0<SUP>3,7</SUP>.0<SUP>44,48</SUP>]nonadecahectan-33-yl]acetic acid IUPAC Name Preferred 1 2.7.0 Lexichem TK OpenEye Scientific Software 2021.05.07 2-[(1R,5aS,7S,10S,13S,16S,19S,21S,24R,27S,30S,33S,36S,39S,42R,48S,54S,57R,60S,63R,66S,72S,78S,81R,87S,93S,96S)-10-(4-aminobutyl)-72-(2-amino-2-oxoethyl)-19-(3-amino-3-oxopropyl)-13,60-bis[(2S)-butan-2-yl]-21,27,30,66-tetrakis(3-carbamimidamidopropyl)-39,96-bis(carboxymethyl)-36,87,93-tris(hydroxymethyl)-78-[(4-hydroxyphenyl)methyl]-54-methyl-16-(2-methylpropyl)-a,2,3a,6a,8,11,14,17,20,22,25,28,31,34,37,40,43,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,97-tetratriacontaoxo-5a-propan-2-yl-9a,10a,13a,14a,17a,18a-hexathia-1a,3,4a,7a,9,12,15,18,23,26,29,32,35,38,41,44,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tritriacontazahexacyclo[55.50.4.424,63.442,81.03,7.044,48]nonadecahectan-33-yl]acetic acid IUPAC Name Systematic 1 2.7.0 Lexichem TK OpenEye Scientific Software 2021.05.07 2-[(1R,5aS,7S,10S,13S,16S,19S,21S,24R,27S,30S,33S,36S,39S,42R,48S,54S,57R,60S,63R,66S,72S,78S,81R,87S,93S,96S)-10-(4-azanylbutyl)-72-(2-azanyl-2-oxidanylidene-ethyl)-19-(3-azanyl-3-oxidanylidene-propyl)-13,60-bis[(2S)-butan-2-yl]-21,27,30,66-tetrakis(3-carbamimidamidopropyl)-36,87,93-tris(hydroxymethyl)-39,96-bis(2-hydroxy-2-oxoethyl)-78-[(4-hydroxyphenyl)methyl]-54-methyl-16-(2-methylpropyl)-a,2,3a,6a,8,11,14,17,20,22,25,28,31,34,37,40,43,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,97-tetratriacontakis(oxidanylidene)-5a-propan-2-yl-9a,10a,13a,14a,17a,18a-hexathia-1a,3,4a,7a,9,12,15,18,23,26,29,32,35,38,41,44,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tritriacontazahexacyclo[55.50.4.424,63.442,81.03,7.044,48]nonadecahectan-33-yl]ethanoic acid IUPAC Name Traditional 1 2.7.0 Lexichem TK OpenEye Scientific Software 2021.05.07 2-[(1R,5aS,7S,10S,13S,16S,19S,21S,24R,27S,30S,33S,36S,39S,42R,48S,54S,57R,60S,63R,66S,72S,78S,81R,87S,93S,96S)-10-(4-aminobutyl)-72-(2-amino-2-keto-ethyl)-19-(3-amino-3-keto-propyl)-39,96-bis(carboxymethyl)-21,27,30,66-tetrakis(3-guanidinopropyl)-78-(4-hydroxybenzyl)-16-isobutyl-5a-isopropyl-a,2,3a,6a,8,11,14,17,20,22,25,28,31,34,37,40,43,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,97-tetratriacontaketo-54-methyl-36,87,93-trimethylol-13,60-bis[(1S)-1-methylpropyl]-9a,10a,13a,14a,17a,18a-hexathia-1a,3,4a,7a,9,12,15,18,23,26,29,32,35,38,41,44,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tritriacontazahexacyclo[55.50.4.424,63.442,81.03,7.044,48]nonadecahectan-33-yl]acetic acid InChI Standard 1 1.0.6 InChI iupac.org 2021.05.07 InChI=1S/C137H218N48O46S6/c1-10-64(7)105-130(228)173-75(40-62(3)4)118(216)165-70(31-32-92(139)190)107(205)69(20-14-34-149-134(141)142)109(207)176-85-57-233-234-58-86-125(223)166-71(22-15-35-150-135(143)144)110(208)155-49-97(195)162-77(42-93(140)191)111(209)156-50-96(194)161-76(41-67-27-29-68(189)30-28-67)119(217)177-84-56-232-236-60-88(179-121(219)80(45-103(203)204)172-123(221)83(55-188)174-120(218)79(44-102(201)202)171-116(214)74(24-17-37-152-137(147)148)167-115(213)73(168-124(85)222)23-16-36-151-136(145)146)132(230)184-38-18-25-90(184)127(225)159-48-95(193)160-66(9)108(206)175-87(126(224)183-106(65(8)11-2)131(229)178-86)59-235-237-61-89(133(231)185-39-19-26-91(185)128(226)169-72(117(215)182-105)21-12-13-33-138)180-129(227)104(63(5)6)181-100(198)47-153-94(192)46-154-112(210)78(43-101(199)200)170-122(220)82(54-187)164-99(197)51-157-113(211)81(53-186)163-98(196)52-158-114(84)212/h27-30,62-66,69-91,104-106,186-189H,10-26,31-61,138H2,1-9H3,(H2,139,190)(H2,140,191)(H,153,192)(H,154,210)(H,155,208)(H,156,209)(H,157,211)(H,158,212)(H,159,225)(H,160,193)(H,161,194)(H,162,195)(H,163,196)(H,164,197)(H,165,216)(H,166,223)(H,167,213)(H,168,222)(H,169,226)(H,170,220)(H,171,214)(H,172,221)(H,173,228)(H,174,218)(H,175,206)(H,176,207)(H,177,217)(H,178,229)(H,179,219)(H,180,227)(H,181,198)(H,182,215)(H,183,224)(H,199,200)(H,201,202)(H,203,204)(H4,141,142,149)(H4,143,144,150)(H4,145,146,151)(H4,147,148,152)/t64-,65-,66-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,104-,105-,106-/m0/s1 InChIKey Standard 1 1.0.6 InChI iupac.org 2021.05.07 CLNWPOLWXUOXRX-SNWIYWKESA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2021.05.07 -17.5 Mass Exact 1 2.1 PubChem ncbi.nlm.nih.gov 2021.05.07 3464.4552635 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2021.05.07 C137H218N48O46S6 Molecular Weight 1 2.1 PubChem ncbi.nlm.nih.gov 2021.05.07 3465.9 SMILES Canonical 1 2.3.0 OEChem OpenEye Scientific Software 2021.05.07 CCC(C)C1C(=O)NC2CSSCC3C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC4CSSCC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(CSSCC(C(=O)N1)NC(=O)C(NC(=O)CNC(=O)C5CCCN5C4=O)C)C(=O)N6CCCC6C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)C(C(=O)N3)CCCNC(=N)N)CCC(=O)N)CC(C)C)C(C)CC)CCCCN)C(C)C)CC(=O)O)CO)CO)NC(=O)C(NC(=O)CNC(=O)C(NC(=O)CNC(=O)C(NC2=O)CCCNC(=N)N)CC(=O)N)CC7=CC=C(C=C7)O)CC(=O)O)CO)CC(=O)O)CCCNC(=N)N)CCCNC(=N)N SMILES Isomeric 1 2.3.0 OEChem OpenEye Scientific Software 2021.05.07 CC[C@H](C)[C@H]1C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]4CSSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]5CCCN5C4=O)C)C(=O)N6CCC[C@H]6C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)[C@@H](C(=O)N3)CCCNC(=N)N)CCC(=O)N)CC(C)C)[C@@H](C)CC)CCCCN)C(C)C)CC(=O)O)CO)CO)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC2=O)CCCNC(=N)N)CC(=O)N)CC7=CC=C(C=C7)O)CC(=O)O)CO)CC(=O)O)CCCNC(=N)N)CCCNC(=N)N Topological Polar Surface Area 7 E_TPSA 3.4.8.18 Cactvs Xemistry GmbH 2021.05.07 1660 Weight MonoIsotopic 1 2.1 PubChem ncbi.nlm.nih.gov 2021.05.07 3463.4519087 237 29 29 0 0 0 0 0 1 -1