456313 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 8 8 8 8 8 8 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 3 4 5 6 7 7 7 8 8 8 9 9 9 10 10 10 11 11 11 11 12 12 12 13 13 14 14 15 15 15 16 16 16 18 18 18 19 19 19 20 20 20 21 21 22 22 24 24 24 25 25 25 27 27 28 28 29 29 29 30 30 31 31 32 32 32 33 33 33 34 34 35 35 36 36 37 37 38 40 41 41 42 42 42 43 43 43 44 44 44 45 45 46 46 47 47 48 48 49 13 65 17 26 32 23 26 39 17 18 62 14 26 64 23 29 74 39 97 98 12 15 17 50 13 51 52 14 53 16 54 21 55 56 22 57 58 19 23 59 20 60 61 24 25 63 27 28 30 31 69 70 71 66 67 68 34 72 35 73 33 39 75 36 76 37 77 42 43 44 41 78 79 38 80 38 81 40 82 40 83 84 85 45 46 92 93 94 89 90 91 86 87 88 47 95 48 96 49 99 49 100 101 1 1 2 1 1 2 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 2 1 1 1 1 1 1 1 2 1 1 1 2 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 11 12 17 15 50 2 1 13 1 14 12 53 2 1 14 8 16 13 54 2 1 18 7 19 23 59 1 1 29 9 33 39 75 1 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 9.4651 6.8671 11.1972 6.001 10.3312 3.403 6.001 9.4651 4.269 2.5369 7.7331 7.7331 8.5991 8.5991 8.5991 7.7331 6.8671 5.135 4.269 4.269 8.5991 7.7331 5.135 3.403 5.135 10.3312 7.7331 9.4651 4.269 6.8671 8.5991 12.0632 5.135 7.7331 9.4651 6.8671 8.5991 8.5991 3.403 7.7331 5.135 12.9292 12.5632 11.5632 4.269 6.001 4.269 6.001 5.135 7.7331 7.1225 7.521 8.5991 8.5991 8.8112 9.2097 7.521 7.1225 5.135 4.0569 3.6584 6.001 4.269 9.4651 9.4651 4.825 5.672 5.445 3.093 2.866 3.713 7.1962 10.0021 3.732 4.8059 6.3301 9.136 5.3471 5.7456 7.1962 10.0021 6.3301 9.136 8.5991 7.7331 12.1002 11.2532 11.0263 12.0263 12.8732 13.1002 13.2392 13.4662 12.6192 3.732 6.538 2 2.5369 3.732 6.538 5.135 -1.25 1.25 -3.25 1.75 -1.75 4.25 -0.25 -3.25 1.75 2.75 -0.25 -1.25 -1.75 -2.75 0.25 -3.25 0.25 0.25 -0.25 -1.25 1.25 -4.25 1.25 -1.75 -1.75 -2.75 1.75 1.75 2.75 -4.75 -4.75 -2.75 3.25 2.75 2.75 -5.75 -5.75 3.25 3.25 -6.25 4.25 -2.25 -3.616 -1.884 4.75 4.75 5.75 5.75 6.25 0.37 -1.1423 -1.8326 -1.13 -3.37 -0.3326 0.3577 -2.6674 -3.3577 -0.37 0.3326 -0.3577 -0.87 -1.87 -3.87 -0.63 -2.2869 -2.06 -1.2131 -1.2131 -2.06 -2.2869 1.44 1.44 1.44 2.44 -4.44 -4.44 2.6674 3.3577 3.06 3.06 -6.06 -6.06 3.87 -6.87 -1.574 -1.347 -2.194 -3.926 -4.153 -3.306 -2.7869 -1.94 -1.7131 4.44 4.44 3.06 2.13 6.06 6.06 6.87 6 5 5 5 8 8 8 8 8 8 6 8 8 8 8 8 8 8 8 8 8 8 8 11 13 14 18 21 21 22 22 27 28 29 30 31 34 35 36 37 41 41 45 46 47 48 12 1 8 7 27 28 30 31 34 35 9 36 37 38 38 40 40 45 46 47 48 49 49 0 Compound Canonicalized 5 2011.04.04 1 Compound Complexity 7 E_COMPLEXITY 3.384 Cactvs xemistry.com 2011.09.13 1030 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.384 Cactvs xemistry.com 2011.09.13 6 Count Hydrogen Bond Donor 5 E_NHDONORS 3.384 Cactvs xemistry.com 2011.09.13 5 Count Rotatable Bond 5 E_NROTBONDS 3.384 Cactvs xemistry.com 2011.09.13 19 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.384 Cactvs xemistry.com 2011.09.13 00000371F07FB8000000000000000000000000000000000000003060C0000000000000015000001E00100800000D7CE19806320882C006008802215218000200002000000888818800890A70328091319C6000249600988807BAC9F09E00000000000000000000000000000000000000000000 IUPAC Name Allowed 1 2.0.2 LexiChem openeye.com 2011.09.13 tert-butyl N-[(1S,2R,4S)-5-[[(1S)-1-[[(1S)-2-amino-1-benzyl-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]amino]-1,4-dibenzyl-2-hydroxy-5-oxo-pentyl]carbamate IUPAC Name CAS-like Style 1 2.0.2 LexiChem openeye.com 2011.09.13 N-[(2S,3R,5S)-6-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-6-oxo-1-phenyl-5-(phenylmethyl)hexan-2-yl]carbamic acid tert-butyl ester IUPAC Name Preferred 1 2.0.2 LexiChem openeye.com 2011.09.13 tert-butyl N-[(2S,3R,5S)-6-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-benzyl-3-hydroxy-6-oxo-1-phenylhexan-2-yl]carbamate IUPAC Name Systematic 1 2.0.2 LexiChem openeye.com 2011.09.13 tert-butyl N-[(2S,3R,5S)-6-[[(2S)-1-[[(2S)-1-azanyl-1-oxidanylidene-3-phenyl-propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-3-oxidanyl-6-oxidanylidene-1-phenyl-5-(phenylmethyl)hexan-2-yl]carbamate IUPAC Name Traditional 1 2.0.2 LexiChem openeye.com 2011.09.13 N-[(1S,2R,4S)-5-[[(1S)-1-[[(1S)-2-amino-1-benzyl-2-keto-ethyl]carbamoyl]-3-methyl-butyl]amino]-1,4-dibenzyl-2-hydroxy-5-keto-pentyl]carbamic acid tert-butyl ester InChI Standard 1 1.0.3 InChI nist.gov 2011.09.13 InChI=1S/C39H52N4O6/c1-26(2)21-33(37(47)41-32(35(40)45)24-29-19-13-8-14-20-29)42-36(46)30(22-27-15-9-6-10-16-27)25-34(44)31(23-28-17-11-7-12-18-28)43-38(48)49-39(3,4)5/h6-20,26,30-34,44H,21-25H2,1-5H3,(H2,40,45)(H,41,47)(H,42,46)(H,43,48)/t30-,31-,32-,33-,34+/m0/s1 InChIKey Standard 1 1.0.3 InChI nist.gov 2011.09.13 MURCDOXDAHPNRQ-PJRHAEEISA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2011.09.13 5.9 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2011.09.13 672.388685 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2011.09.13 C39H52N4O6 Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2011.09.13 672.85338 SMILES Canonical 1 1.7.4 OEChem openeye.com 2011.09.13 CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC2=CC=CC=C2)CC(C(CC3=CC=CC=C3)NC(=O)OC(C)(C)C)O SMILES Isomeric 1 1.7.4 OEChem openeye.com 2011.09.13 CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)NC(=O)[C@@H](CC2=CC=CC=C2)C[C@H]([C@H](CC3=CC=CC=C3)NC(=O)OC(C)(C)C)O Topological Polar Surface Area 7 E_TPSA 3.384 Cactvs xemistry.com 2011.09.13 160 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2011.09.13 672.388685 49 5 5 0 0 0 0 0 1 24