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Compound Summary for: CID 4528

Nomifensine

Also known as: nomifensin; Linamiphen; 24526-64-5; (+-)-Nomifensin; (+-)-Nomifensine; 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine
Molecular Formula: C16H18N2   Molecular Weight: 238.32752   InChIKey: XXPANQJNYNUNES-UHFFFAOYSA-N
An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)   From: MeSH
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