4484463 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 16 9 8 8 8 8 8 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 3 4 4 5 6 7 7 8 8 8 9 9 10 10 10 11 11 12 12 13 15 17 17 18 18 19 19 20 21 22 23 23 23 23 24 24 24 25 25 26 26 27 27 28 28 29 30 30 30 31 31 31 32 32 33 33 34 34 34 35 36 36 37 37 38 38 38 39 40 41 41 41 16 28 39 21 25 15 58 13 14 20 41 10 14 16 16 29 11 12 42 13 15 17 18 14 19 20 43 22 44 26 27 21 22 46 24 30 31 45 25 47 48 49 50 33 34 32 51 29 36 37 55 56 57 52 53 54 35 38 35 59 60 61 62 63 39 64 40 65 66 67 68 40 69 70 71 72 1 1 1 1 1 1 1 2 2 1 1 1 1 1 2 1 1 1 1 1 2 2 1 1 1 1 1 2 1 2 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 10 8 11 12 42 3 1 11 10 13 15 4 19 3 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 5.5443 2 6.4796 9.3712 9.4758 7.4067 5.1414 7.1279 5.5443 7.7157 8.6668 7.4067 8.6668 7.7157 9.4758 6.1279 6.4285 8.0758 10.3893 6.1195 6.7886 7.7668 7.5089 6.8397 7.1488 11.1983 10.4938 4.5981 4.5981 7.1998 8.487 11.4074 12.1119 11.0938 12.2164 3.732 3.732 11.5119 2.866 2.866 4.8323 7.1033 6.0137 8.6822 7.9237 8.1816 6.2923 6.458 7.6962 7.5305 9.9922 8.6159 9.0935 8.3581 6.6102 7.0083 7.7895 9.8728 12.6135 10.4772 11.029 11.7104 12.7828 3.732 3.732 12.1285 11.5767 10.8953 2.3291 4.2427 4.6408 5.422 3.9255 4.1208 -1.4925 1.0385 4.2086 4.8809 -0.0062 3.1208 2.316 2.3118 2.6208 1.3607 3.6208 3.9298 2.033 3.1208 1.1528 0.6176 2.4397 0.2017 -0.5414 -0.3335 -3.9298 -3.1867 -2.2356 1.852 3.4343 3.6208 2.6208 -4.8809 -3.7219 3.841 2.2587 0.8574 3.2532 4.1208 2.1208 4.8355 3.6208 2.6208 -0.9572 2.2148 1.6136 0.7465 -4.3906 -0.7942 -2.8956 -3.6752 -2.5267 -1.747 3.7987 -4.3283 -3.593 -3.1154 -4.6893 -5.4705 -5.0724 0.6741 1.8943 0.9222 0.2408 0.7926 3.5054 4.7408 1.5008 4.7707 5.4521 4.9003 2.3108 -0.7656 -1.5469 -1.1488 8 8 8 8 3 1 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 1 1 9 9 10 11 12 12 17 18 19 19 20 21 26 27 28 28 29 32 33 36 37 39 16 28 16 29 12 15 17 18 20 22 26 27 21 22 33 32 29 36 37 35 35 39 40 40 0 Compound Canonicalized 5 2011.04.04 1 Compound Complexity 7 E_COMPLEXITY 3.402 Cactvs xemistry.com 2012.05.21 993 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.402 Cactvs xemistry.com 2012.05.21 8 Count Hydrogen Bond Donor 5 E_NHDONORS 3.402 Cactvs xemistry.com 2012.05.21 1 Count Rotatable Bond 5 E_NROTBONDS 3.402 Cactvs xemistry.com 2012.05.21 8 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.402 Cactvs xemistry.com 2012.05.21 00000371E07F3900400000000000000000000000000162C000003060C000000000005801F400001F04000800000D2CE1DE0E33D7B3081608AC03A572740083F8A9612A3849983DBEECD88D26BAE4B9BB86782AECC713CAF927BCD8F38EE000030000104100C000060000208200000000000000 IUPAC Name Allowed 1 2.1.0 LexiChem openeye.com 2012.05.21 4-[(2,5-dimethylphenyl)-hydroxy-methylene]-1-(6-fluoro-1,3-benzothiazol-2-yl)-5-(4-isopentyloxy-3-methoxy-phenyl)pyrrolidine-2,3-dione IUPAC Name CAS-like Style 1 2.1.0 LexiChem openeye.com 2012.05.21 4-[(2,5-dimethylphenyl)-hydroxymethylidene]-1-(6-fluoro-1,3-benzothiazol-2-yl)-5-[3-methoxy-4-(3-methylbutoxy)phenyl]pyrrolidine-2,3-dione IUPAC Name Preferred 1 2.1.0 LexiChem openeye.com 2012.05.21 4-[(2,5-dimethylphenyl)-hydroxymethylidene]-1-(6-fluoro-1,3-benzothiazol-2-yl)-5-[3-methoxy-4-(3-methylbutoxy)phenyl]pyrrolidine-2,3-dione IUPAC Name Systematic 1 2.1.0 LexiChem openeye.com 2012.05.21 4-[(2,5-dimethylphenyl)-oxidanyl-methylidene]-1-(6-fluoranyl-1,3-benzothiazol-2-yl)-5-[3-methoxy-4-(3-methylbutoxy)phenyl]pyrrolidine-2,3-dione IUPAC Name Traditional 1 2.1.0 LexiChem openeye.com 2012.05.21 4-[(2,5-dimethylphenyl)-hydroxy-methylene]-1-(6-fluoro-1,3-benzothiazol-2-yl)-5-(4-isoamoxy-3-methoxy-phenyl)pyrrolidine-2,3-quinone InChI Standard 1 1.0.4 InChI iupac.org 2012.05.21 InChI=1S/C32H31FN2O5S/c1-17(2)12-13-40-24-11-8-20(15-25(24)39-5)28-27(29(36)22-14-18(3)6-7-19(22)4)30(37)31(38)35(28)32-34-23-10-9-21(33)16-26(23)41-32/h6-11,14-17,28,36H,12-13H2,1-5H3 InChIKey Standard 1 1.0.4 InChI iupac.org 2012.05.21 JNIUAOFLSIVNEI-UHFFFAOYSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.05.21 7.8 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 574.193771 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 C32H31FN2O5S Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 574.662343 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.05.21 CC1=CC(=C(C=C1)C)C(=C2C(N(C(=O)C2=O)C3=NC4=C(S3)C=C(C=C4)F)C5=CC(=C(C=C5)OCCC(C)C)OC)O SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.05.21 CC1=CC(=C(C=C1)C)C(=C2C(N(C(=O)C2=O)C3=NC4=C(S3)C=C(C=C4)F)C5=CC(=C(C=C5)OCCC(C)C)OC)O Topological Polar Surface Area 7 E_TPSA 3.402 Cactvs xemistry.com 2012.05.21 117 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 574.193771 41 1 0 1 1 0 1 0 1 14