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Compound Summary for: CID 446541     Try the new version summary page

Mycophenolic Acid

Also known as: 24280-93-1; Mycophenolate; Myfortic; Melbex; Mycophenolsaeure; Lilly-68618; Acido micofenolico; Micofenolico acido
Molecular Formula: C17H20O6   Molecular Weight: 320.3371   InChIKey: HPNSFSBZBAHARI-RUDMXATFSA-N
An antibiotic substance derived from Penicillium stoloniferum, and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase. Mycophenolic acid is important because of its selective effects on the immune system. It prevents the proliferation of T-cells, lymphocytes, and the formation of antibodies from B-cells. It also may inhibit recruitment of leukocytes to inflammatory sites. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1301)   From: MeSH
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Use and Manufacturing
Biomedical Effects and Toxicity
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