Bookmark and Share

Compound Summary for: CID 446541     Try the new version summary page

Mycophenolic Acid

Also known as: 24280-93-1; Mycophenolate; Myfortic; Melbex; Mycophenolsaeure; Lilly-68618; Acido micofenolico; Micofenolico acido
Molecular Formula: C17H20O6   Molecular Weight: 320.3371   InChIKey: HPNSFSBZBAHARI-RUDMXATFSA-N
An antibiotic substance derived from Penicillium stoloniferum, and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase. Mycophenolic acid is important because of its selective effects on the immune system. It prevents the proliferation of T-cells, lymphocytes, and the formation of antibodies from B-cells. It also may inhibit recruitment of leukocytes to inflammatory sites. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1301)   From: MeSH
Show subcontent titlesTable of Contents
Identification
Related Records
show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)
Use and Manufacturing
Pharmacology
Biomedical Effects and Toxicity
Literature
Patents
Biomolecular Interactions and Pathways
Biological Test Results
Classification
Chemical and Physical Properties
_ _