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Compound Summary for: CID 446155

fluvastatin

Also known as: Lescol; 93957-54-1; Cranoc; CHEBI:38565; T6624179; CHEMBL1078; Canef; Fluvastatin & Primycin; XU 62320
Molecular Formula: C24H26FNO4   Molecular Weight: 411.465943   InChIKey: FJLGEFLZQAZZCD-MCBHFWOFSA-N
Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It is also the first entirely synthetic HMG-CoA reductase inhibitor and is structurally distinct from the fungal derivatives of this therapeutic class.    From: DrugBank
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