44593582 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 16 16 16 16 16 16 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 3 4 5 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 21 22 22 23 24 25 26 26 27 28 29 30 31 32 32 33 34 34 35 36 37 37 38 39 40 41 42 43 44 44 45 46 47 48 48 49 50 50 50 51 51 51 52 52 52 53 53 53 54 54 54 55 55 55 56 56 56 57 57 57 58 58 58 59 59 59 60 60 60 61 61 61 62 62 62 63 63 63 64 64 64 65 65 65 66 66 66 67 67 67 68 68 68 69 69 69 70 70 70 71 71 71 72 72 72 73 73 73 74 74 74 75 75 75 76 76 76 77 77 77 78 78 78 79 79 80 80 80 81 81 81 82 82 82 83 83 83 84 84 84 85 85 85 86 86 86 87 87 87 88 88 88 89 89 89 90 90 90 91 91 91 92 92 93 93 93 94 94 94 95 95 96 96 96 97 97 97 100 100 100 101 101 101 104 104 104 105 105 105 106 106 106 107 107 107 108 108 108 109 110 111 111 111 112 112 112 113 113 114 114 115 115 115 116 116 116 117 117 117 118 118 119 119 122 122 122 123 123 124 125 125 125 126 126 127 127 127 128 128 129 130 130 130 131 132 132 133 134 134 135 135 135 136 136 136 138 138 139 139 139 140 140 140 141 141 141 142 142 143 143 144 145 145 146 146 146 148 149 149 149 150 150 151 151 151 152 153 153 154 154 156 156 157 157 158 158 159 159 160 160 160 161 161 162 162 162 165 165 165 166 166 166 167 167 168 168 171 171 171 174 174 174 176 177 177 178 179 179 179 180 180 180 181 181 181 182 182 182 183 183 183 184 185 185 186 186 187 187 187 188 188 189 191 191 193 193 193 194 194 194 195 195 195 196 196 196 197 197 197 198 198 198 199 199 200 200 200 202 203 203 204 205 205 205 206 206 206 207 207 208 208 211 211 211 212 212 212 214 214 214 215 215 215 216 216 216 218 218 219 219 220 220 221 221 221 223 223 223 224 225 225 226 226 226 227 227 228 228 228 230 230 230 231 231 232 232 232 233 233 234 234 236 236 237 237 239 3 118 4 119 146 151 6 161 199 98 99 102 103 109 110 120 121 124 129 137 144 147 152 155 364 159 371 155 163 164 175 393 169 170 172 173 176 185 412 184 191 426 190 192 201 432 201 202 209 210 213 217 222 451 224 229 235 238 459 238 88 91 98 89 94 99 96 109 262 97 110 263 102 108 270 103 111 271 113 124 290 114 129 293 120 127 294 121 136 299 131 133 307 126 144 308 132 152 320 137 149 323 134 327 328 147 160 336 150 173 345 154 170 346 153 176 347 164 165 353 156 184 355 163 181 360 171 172 361 169 183 368 177 202 377 178 204 378 190 193 398 186 210 399 192 197 400 189 204 205 209 413 203 224 419 213 221 427 225 229 438 217 439 440 218 443 444 231 454 455 235 457 458 90 102 240 93 103 241 92 242 243 92 244 245 246 247 95 248 249 95 250 251 252 253 98 100 254 99 101 255 104 106 256 105 107 257 112 258 259 115 260 261 264 265 266 267 268 269 118 120 272 113 114 119 121 273 274 275 276 117 277 116 278 279 280 281 122 282 283 123 284 285 286 287 288 289 125 291 292 128 131 126 134 295 296 130 297 135 137 298 133 138 132 139 140 300 301 141 302 142 303 304 143 305 306 147 309 310 145 311 314 316 317 312 313 315 155 318 319 148 321 157 158 150 148 322 153 324 325 326 159 163 329 161 330 156 331 332 154 164 333 162 334 169 335 167 337 168 338 174 339 166 172 340 341 342 178 343 344 170 179 348 180 349 350 175 351 175 352 173 185 354 356 357 358 177 182 359 189 188 362 363 201 365 366 190 191 367 194 195 369 187 192 370 186 372 373 200 374 196 375 376 207 208 379 380 381 198 209 382 386 387 388 383 384 385 206 389 390 199 213 391 211 214 392 394 395 217 396 397 203 212 401 402 210 215 403 218 404 405 219 406 220 407 223 408 409 216 410 411 414 415 416 227 417 418 226 420 421 422 423 222 424 222 425 228 229 428 429 430 431 225 230 433 231 434 435 233 234 232 436 437 235 441 442 445 446 238 447 448 236 449 237 450 239 452 239 453 456 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 2 2 1 1 1 1 2 2 2 1 1 2 2 2 2 2 1 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 1 2 2 2 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 1 1 1 88 50 90 102 240 1 1 89 51 93 103 241 1 1 96 52 100 98 254 2 1 97 53 101 99 255 2 1 100 96 106 104 256 2 1 101 97 107 105 257 2 1 108 54 118 120 272 1 1 111 55 119 121 273 1 1 113 56 117 109 277 2 1 114 57 116 110 278 2 1 126 61 130 124 297 2 1 127 58 135 137 298 1 1 132 62 141 129 302 2 1 149 63 159 163 329 1 1 150 66 161 144 330 2 1 153 68 146 164 333 1 1 154 67 162 152 334 2 1 156 70 151 169 335 1 1 159 22 149 174 339 1 1 160 65 166 172 340 1 1 165 69 179 170 348 2 1 171 72 185 173 354 2 1 177 74 182 176 359 2 1 181 71 191 190 367 2 1 183 73 187 192 370 1 1 186 77 200 184 374 2 1 193 76 198 209 382 1 1 197 78 199 213 391 1 1 198 193 214 211 392 2 1 203 81 212 202 401 2 1 205 80 215 210 403 2 1 221 82 228 229 428 1 1 225 83 230 224 433 2 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 9.2894 31.8862 8.3492 32.1665 26.4478 26.4129 16.0458 25.423 12.9024 29.3115 19.2529 20.009 11.7354 29.2548 22.4885 14.4827 14.6851 25.7172 27.8438 9.7372 11.8343 16.1141 11.3295 17.7355 5.4051 13.1254 32.559 6.539 27.155 25.9495 6.5186 25.392 30.5879 19.2735 20.8531 29.8161 26.8963 25.7533 9.6995 24.0038 26.9788 25.3763 28.8912 2.5338 14.434 19.9571 14.7593 23.1245 21.3981 15.2112 26.4922 18.2979 21.6873 12.1974 29.7157 21.4235 16.499 13.0761 29.6424 18.3796 24.5538 11.7656 15.9639 18.4886 28.3761 26.7699 8.2519 6.8657 6.5256 31.0443 18.9383 27.4151 30.9648 9.2172 6.9897 21.9668 28.0532 27.834 6.1867 25.0163 13.2001 23.3266 18.171 30.6172 33.3676 8.676 15.682 14.1969 27.3012 14.1579 15.6966 15.0617 28.1102 26.8012 27.8012 17.263 23.3724 16.2337 24.9838 17.3705 23.4304 13.1919 28.5928 16.5632 24.3239 18.2852 22.5948 11.2147 19.3371 19.959 30.6496 16.6707 20.3794 18.2191 24.3818 17.8792 20.5902 10.245 31.3775 12.1383 30.1301 18.5238 19.8491 22.4681 18.1839 23.512 14.0271 19.9568 14.8301 23.307 18.8763 13.2427 19.0437 18.8285 13.457 29.1872 14.9901 20.7665 24.0521 23.1019 13.0168 18.9405 13.3741 25.5924 20.6632 7.4254 28.7649 19.7502 16.9473 26.6264 32.2132 10.4257 6.5192 9.2473 12.0602 32.0255 14.1957 12.4696 16.969 28.0212 26.519 8.6561 17.9392 6.4051 6.8786 27.3641 14.1128 12.3867 31.6068 7.4575 27.1645 27.7008 26.9494 17.3314 13.2083 7.4385 8.2271 7.662 6.0175 27.5192 19.9434 7.5301 30.111 30.0544 26.1898 29.0569 31.0607 5.1466 7.1657 20.9533 20.0695 29.0611 22.9826 6.5606 7.8026 31.2645 26.4521 22.6943 26.4143 29.8785 26.7412 10.3908 11.7265 6.0779 26.0316 32.2142 4.2856 5.1367 23.9995 27.0443 21.7209 11.3682 24.9405 23.3795 26.3612 10.3805 29.7957 32.4179 3.4146 4.2658 21.6399 3.4048 21.4327 14.7849 16.4519 10.0221 25.7084 21.5593 19.9109 16.4901 9.0344 22.3822 26.038 24.726 15.6438 25.3852 24.0731 22.3016 24.4027 13.9794 27.3012 13.996 13.545 16.1957 16.1177 15.5734 14.771 28.4202 28.6766 26.866 26.1948 28.4077 27.7364 16.9196 23.8394 17.871 23.4663 16.2898 15.9677 24.5019 24.9397 18.2241 21.8013 18.0347 18.8524 18.5357 22.9354 22.0767 22.2542 11.9973 30.2152 10.9125 31.0736 16.0543 16.7373 17.2871 20.1896 18.3281 25.0008 24.4178 23.7629 17.4818 17.3416 20.9203 21.1644 9.7488 10.4856 31.9873 30.7982 21.4145 18.9212 19.0614 16.3638 12.8463 17.7865 17.6463 23.7053 13.9757 29.0896 22.7001 18.6234 12.8194 19.2259 19.3661 12.8588 14.0405 17.7629 24.6097 28.8338 29.7495 21.3326 22.4951 22.9748 23.6386 23.7087 24.5141 24.4656 13.6359 13.0917 11.403 18.3744 21.1653 15.7955 6.893 7.7244 19.6862 18.8883 17.8783 16.5384 27.4678 32.7295 31.5937 5.6767 8.6799 32.8456 28.2782 14.7565 11.9602 16.4255 27.9074 26.0127 27.1367 9.2122 8.4826 26.1574 7.7206 6.2678 6.2586 26.7903 27.0033 14.6222 11.8259 5.9114 26.8398 31.1969 17.9092 17.556 16.7535 7.6306 18.8332 26.9773 6.4207 5.6237 11.2412 28.1057 27.819 19.7036 31.5243 8.1312 30.5239 16.1275 26.4641 25.712 29.0056 31.6805 31.1497 8.7323 7.116 7.4203 20.6617 20.3534 23.1774 7.206 7.9715 8.3991 6.7126 5.9595 6.4086 30.6448 31.1756 26.922 22.5156 12.5646 25.8734 27.0342 30.1382 30.4781 21.9262 28.3466 28.2431 11.2447 5.5397 26.236 32.8339 32.3031 4.2917 5.6706 21.1053 21.6859 11.3573 11.9768 24.821 25.0405 23.8311 23.8042 22.9278 26.9022 26.7534 12.9065 10.3913 9.7719 31.7982 32.329 2.8808 4.2597 19.3517 23.5193 21.9056 22.0263 21.2539 20.839 26.4139 16.1627 10.0113 10.6307 20.9594 21.301 18.1161 31.178 30.5659 16.7243 17.0962 33.494 33.8302 9.0452 8.4258 22.9821 22.6405 26.6471 24.5216 2 25.5895 23.464 8.0637 9.0662 23.998 15.1573 16.2304 23.0745 -3.7955 2.3124 -3.3404 0.5948 -8.2543 -9.2952 -7.0111 11.8756 -6.2373 9.0504 -7.4521 13.2713 -3.2648 5.1382 -7.5554 12.4225 -2.147 -7.32 2.2352 9.4662 13.0114 -1.0287 11.3545 -1.3436 -0.5947 1.3815 -4.8695 4.8802 -0.2526 -4.1059 -6.0738 -3.4822 -1.5287 -0.3808 -0.8635 -9.7414 3.2582 2.4255 -10.6718 -0.7119 -0.8867 -13.1397 -0.183 1.3864 -13.6457 -14.5152 -14.2741 -16.4487 -16.3092 -5.8148 10.1093 -6.3496 12.0688 -4.9603 7.0257 -6.5588 11.9779 -3.7868 3.7344 -8.8308 -6.4401 9.8515 -2.8062 16.5927 0.8795 -5.1478 6.033 -4.0384 1.1395 -2.6075 -2.1329 -2.0921 -6.1815 -8.6642 8.8985 -1.7742 -2.0128 -10.3197 7.4938 -1.734 -11.9903 -12.8908 -13.4793 -0.0395 -10.5952 -14.1782 -15.74 -5.5651 9.5215 -4.5941 -4.9729 -4.2372 10.1093 11.0603 11.0603 -6.2073 11.6343 -6.0289 10.9772 -7.2015 12.6326 -5.2802 8.3551 -7.7917 13.0816 -7.6055 13.182 -4.606 -6.4557 12.2726 5.5573 -8.7859 -6.5254 12.2421 14.0799 13.1826 -7.503 -4.2175 3.9766 -4.1801 4.6546 13.9472 -8.1743 -6.5557 14.8877 -6.5161 -3.4264 -9.1625 11.4848 -7.4948 -7.9697 10.7717 -9.5704 15.6522 -2.6048 2.7977 -3.0994 -9.7493 -8.1618 -8.4736 11.7458 -10.565 -1.6082 -6.3278 -10.7439 -2.8527 1.8457 -11.1518 -2.5472 -6.1794 -1.1448 8.741 -2.3331 7.4605 12.0372 -2.8749 -1.0381 -1.1817 -1.5474 -0.0996 -7.2153 8.267 -2.3227 -0.5966 2.8436 0.6542 -0.0416 -0.1852 -4.564 4.4847 -3.1029 -1.0905 -4.1219 -0.6154 0.3849 -5.6817 -7.233 8.1582 3.3521 1.6421 -1.9781 -7.9501 -7.6979 -2.3745 -2.8793 -2.1761 -8.011 2.8607 7.29 -1.8585 -0.9861 -9.0857 -1.7253 -7.705 -8.9122 -8.99 -11.3774 -0.7677 -10.3366 -1.6061 2.2703 -9.9492 -11.0646 8.4878 -1.7915 -9.3031 3.3692 1.8607 -1.7119 -1.8845 -0.5386 -11.9982 -12.2397 -0.0393 -0.8474 -12.1546 -0.6095 -10.2821 2.8778 1.3693 -13.3189 1.8778 0.4189 -12.7093 -13.2087 -13.0882 -0.0899 -14.3157 -13.5163 -14.208 -13.2446 -14.8838 0.8542 -0.2765 -14.7407 1.6117 0.481 -15.8806 1.4251 -6.3868 8.6715 -3.9956 -4.6881 -5.3406 -4.5179 -3.8871 -3.6896 9.5723 10.3615 11.6769 11.1892 11.1892 11.6769 -6.9848 12.3446 -6.8356 13.2516 -7.2352 -7.9643 12.4877 13.1537 -6.9652 12.6782 -8.1726 -7.856 -7.0383 13.7 13.5226 12.6639 -5.5471 7.3929 -5.4004 6.294 -8.8525 -9.4023 -8.7192 -7.1156 12.8525 14.044 14.6989 14.1159 13.6585 12.8739 -8.0278 -7.269 -4.5892 -3.6461 3.8644 3.7558 -7.1787 13.4713 14.2559 12.583 -3.2109 15.3635 14.5789 -7.1052 -2.8085 4.0151 -7.3677 -7.4036 11.2247 15.1763 15.961 -2.4417 -2.3952 -8.8953 -7.0576 3.3071 2.5364 -9.4964 -8.3465 -9.0804 -8.6238 -8.6007 -8.5752 -7.6998 11.7789 12.3613 10.3545 -10.8179 -11.1077 -2.2095 -3.1705 -2.3095 -11.7685 17.0667 16.7018 -1.802 -6.0586 -1.488 -1.1196 -2.4458 7.7102 -3.0984 1.4918 -1.3026 -1.5352 -1.8457 0.5098 -6.8574 -7.2684 8.5411 8.8622 -5.0517 6.3526 -4.2026 2.8497 0.889 0.15 0.3119 0.0793 1.224 -2.5748 -2.0065 -0.8401 -0.0375 -0.3907 -7.402 -1.5218 -2.5311 3.8231 3.831 13.1921 1.441 2.1848 -1.4064 -6.4485 -8.102 -8.1604 -0.4089 -2.3233 -2.4842 -1.5583 -7.992 -7.3974 -9.0505 9.5055 6.7247 -1.1699 -0.4349 -0.8979 -9.0812 -9.5088 -8.7433 -7.1039 -7.553 -8.306 -9.009 -9.6036 -12.0857 -0.1741 1.6459 -10.0336 -10.325 -2.1691 -1.4482 -1.1555 -1.4666 -10.7855 -11.4548 8.7955 -1.2062 -9.2841 -8.6895 3.9892 1.5454 -0.6115 -1.1576 -12.6181 -12.1165 -3.2407 -1.1144 -0.4641 0.4123 0.3855 -1.1503 -0.3673 -12.5363 -11.5347 -12.0363 -10.3011 -10.8957 3.1931 0.7493 0.2342 -13.4801 -13.8791 0.5977 1.0126 0.2402 3.6478 -13.7571 -13.7081 -13.2065 -14.1591 -14.8793 -14.0969 -0.3039 0.5784 -14.7821 -14.0771 -11.2022 -10.1823 -12.6247 -13.1263 -15.0403 -14.3202 0.9699 -0.8619 1.7017 2.1971 0.3653 -14.2752 -14.66 1.8948 -16.0702 -16.0292 -17.0667 8 8 8 8 8 8 5 6 6 6 5 5 6 6 5 5 8 8 5 5 8 8 5 8 8 8 8 8 8 6 6 5 5 6 8 8 6 6 5 8 8 6 5 8 5 5 5 8 8 6 5 6 5 5 8 8 8 8 5 5 8 8 8 8 8 8 60 60 75 75 79 79 88 89 96 97 100 101 108 111 113 114 123 123 126 127 128 128 132 133 138 142 143 143 145 149 150 153 154 156 157 158 159 160 165 167 168 171 177 178 181 183 186 188 188 193 197 198 203 205 207 208 219 220 221 225 227 227 233 234 236 237 131 133 178 204 189 204 240 241 254 255 106 107 272 273 117 116 128 131 130 135 133 138 141 142 145 148 157 158 148 329 330 333 162 335 167 168 22 166 179 175 175 185 182 189 191 187 200 207 208 382 391 214 212 215 219 220 222 222 228 230 233 234 236 237 239 239 0 Compound Canonicalized 5 2010.07.16 0 Compound Complexity 7 E_COMPLEXITY 3.402 Cactvs xemistry.com 2012.05.21 8040 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.402 Cactvs xemistry.com 2012.05.21 53 Count Hydrogen Bond Donor 5 E_NHDONORS 3.402 Cactvs xemistry.com 2012.05.21 43 Count Rotatable Bond 5 E_NROTBONDS 3.402 Cactvs xemistry.com 2012.05.21 45 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.402 Cactvs xemistry.com 2012.05.21 00000371F07FFE00700000000000000000000000000162C58B003060C180000000005801FC00001E04100800000D3CE5DE06BFDEF7C99200A80335F77C0082802DB132A009D9A1BE7C988A7EFEC2D9B39470086EF613D8D827BFDFE28EA0000000000200004000000000040000000000000000 InChI Standard 1 1.0.4 InChI iupac.org 2012.05.21 InChI=1S/C152H220N38O43S6/c1-12-76(8)120-149(230)173-95(54-80-28-16-15-17-29-80)131(212)171-100(60-113(157)197)134(215)178-106-69-235-234-67-104-124(205)160-64-114(198)162-92(45-47-115(199)200)126(207)175-102(65-191)138(219)179-109-72-239-236-68-105(177-125(206)89(165-140(106)221)32-20-23-49-153)141(222)166-93(46-48-116(201)202)127(208)170-99(59-112(156)196)133(214)163-90(33-21-24-50-154)128(209)183-119(75(6)7)148(229)182-108(143(224)167-94(55-81-37-41-85(194)42-38-81)130(211)169-98(58-84-63-158-73-161-84)132(213)172-101(61-117(203)204)135(216)164-91(34-22-25-51-155)129(210)186-121(77(9)13-2)151(232)189-52-26-35-110(189)145(226)180-104)71-238-237-70-107(142(223)168-96(56-82-39-43-86(195)44-40-82)136(217)188-123(79(11)193)150(231)176-103(66-192)139(220)185-120)181-146(227)111-36-27-53-190(111)152(233)122(78(10)14-3)187-137(218)97(174-147(228)118(74(4)5)184-144(109)225)57-83-62-159-88-31-19-18-30-87(83)88/h15-19,28-31,37-44,62-63,73-79,89-111,118-123,159,191-195H,12-14,20-27,32-36,45-61,64-72,153-155H2,1-11H3,(H2,156,196)(H2,157,197)(H,158,161)(H,160,205)(H,162,198)(H,163,214)(H,164,216)(H,165,221)(H,166,222)(H,167,224)(H,168,223)(H,169,211)(H,170,208)(H,171,212)(H,172,213)(H,173,230)(H,174,228)(H,175,207)(H,176,231)(H,177,206)(H,178,215)(H,179,219)(H,180,226)(H,181,227)(H,182,229)(H,183,209)(H,184,225)(H,185,220)(H,186,210)(H,187,218)(H,188,217)(H,199,200)(H,201,202)(H,203,204)/t76-,77-,78-,79+,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,118-,119-,120-,121-,122-,123-/m0/s1 InChIKey Standard 1 1.0.4 InChI iupac.org 2012.05.21 MSVJOJFCJSDVQL-BDXIEVRTSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.05.21 -10.3 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 3458.455429 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 C152H220N38O43S6 Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 3459.992 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.05.21 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC2CSSCC3C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC4CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CO)C(C)O)CC5=CC=C(C=C5)O)NC(=O)C6CCCN6C(=O)C(NC(=O)C(NC(=O)C(NC4=O)C(C)C)CC7=CNC8=CC=CC=C87)C(C)CC)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N9CCCC9C(=O)N3)C(C)CC)CCCCN)CC(=O)O)CC1=CN=CN1)CC1=CC=C(C=C1)O)C(C)C)CCCCN)CC(=O)N)CCC(=O)O)NC(=O)C(NC2=O)CCCCN)CO)CCC(=O)O)CC(=O)N)CC1=CC=CC=C1 SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.05.21 CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]2CSSC[C@H]3C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]4CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CO)[C@@H](C)O)CC5=CC=C(C=C5)O)NC(=O)[C@@H]6CCCN6C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC4=O)C(C)C)CC7=CNC8=CC=CC=C87)[C@@H](C)CC)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N9CCC[C@H]9C(=O)N3)[C@@H](C)CC)CCCCN)CC(=O)O)CC1=CN=CN1)CC1=CC=C(C=C1)O)C(C)C)CCCCN)CC(=O)N)CCC(=O)O)NC(=O)[C@@H](NC2=O)CCCCN)CO)CCC(=O)O)CC(=O)N)CC1=CC=CC=C1 Topological Polar Surface Area 7 E_TPSA 3.402 Cactvs xemistry.com 2012.05.21 1430 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 3457.452074 239 33 33 0 0 0 0 0 1 1000