4451895 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 17 17 9 8 8 8 8 8 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 3 4 5 6 7 8 8 9 9 9 10 10 10 11 11 11 11 12 12 12 13 13 13 14 14 15 15 16 16 16 17 18 18 18 19 19 19 20 25 25 26 26 26 27 27 28 28 29 29 30 30 31 31 32 32 32 34 34 35 35 36 36 36 37 37 37 38 38 39 39 13 14 40 21 22 23 24 33 67 21 24 26 22 23 29 12 15 17 41 18 21 42 14 15 22 16 23 43 44 17 25 45 20 19 24 46 20 47 48 49 27 28 32 50 51 30 52 31 53 34 35 33 36 33 37 54 55 56 38 57 39 58 59 60 61 62 63 64 40 65 40 66 1 1 1 2 2 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 2 1 1 1 1 1 1 2 1 2 1 2 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 2 1 1 1 11 12 15 17 41 3 1 12 11 18 21 42 3 1 13 1 14 15 22 3 1 14 2 13 16 23 3 1 16 14 17 25 45 3 1 18 12 19 24 46 3 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 8.5991 6.001 10.065 8.633 9.4486 6.4084 5.5487 2.5369 7.2415 8.065 6.8671 6.8831 7.7331 6.8671 7.7331 6.001 6.001 5.9851 5.083 5.091 7.6562 8.4701 7.0763 6.2108 5.135 7.7481 5.135 4.269 8.565 4.269 3.403 7.2548 3.403 9.565 8.065 4.269 2.5369 10.065 8.565 9.565 7.4064 7.4469 7.9451 8.3437 5.4641 5.4854 4.473 4.8695 4.5577 8.2261 8.22 5.672 4.269 6.7155 6.949 7.7941 9.875 7.445 4.889 4.269 3.649 2.2269 2 2.8469 10.685 8.255 2 -0.0639 1.4361 5.4751 -2.5805 0.897 2.6522 -4.3931 2.4361 -3.7431 2.011 -1.0639 -2.1054 0.4361 0.9361 -0.5639 0.4361 -0.5639 -2.6331 -2.1123 -1.0707 -2.7943 1.1032 1.9079 -3.6437 0.9361 -4.6052 1.9361 0.4361 2.877 2.4361 0.9361 -5.4751 1.9361 2.877 3.743 3.4361 0.4361 3.743 4.6091 4.6091 -1.3697 -1.8474 -1.1465 -0.4562 0.1261 -3.0001 -2.0015 -2.6944 -0.7545 -5.0001 -4.2031 2.2461 -0.1839 -5.1692 -6.0144 -5.781 2.3401 3.743 3.4361 4.0561 3.4361 0.9731 0.1261 -0.1008 3.743 5.146 2.1261 3 3 3 3 3 3 8 8 8 8 8 8 8 8 8 8 8 8 11 12 13 14 16 18 25 25 27 28 29 29 30 31 34 35 38 39 15 21 1 2 25 19 27 28 30 31 34 35 33 33 38 39 40 40 0 Compound Canonicalized 5 2011.04.04 1 Compound Complexity 7 E_COMPLEXITY 3.396 Cactvs xemistry.com 2012.02.08 1160 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.396 Cactvs xemistry.com 2012.02.08 6 Count Hydrogen Bond Donor 5 E_NHDONORS 3.396 Cactvs xemistry.com 2012.02.08 1 Count Rotatable Bond 5 E_NROTBONDS 3.396 Cactvs xemistry.com 2012.02.08 3 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.396 Cactvs xemistry.com 2012.02.08 00000371E07B3900060000000000000000000000000162C000003060C1000000000058814000001F02000800000D0EC1980C32C6830002008802255250008200002122000888410C6E88482632C39193C4700864C631C8D8079DC8F08EA000020000080000C800044000320008000000000000 IUPAC Name Allowed 1 2.1.0 LexiChem openeye.com 2012.02.08 6a,9a-dichloro-2-ethyl-8-(4-fluorophenyl)-6-(4-hydroxy-3,5-dimethyl-phenyl)-3a,4,6,10,10a,10b-hexahydroisoindolo[5,6-e]isoindole-1,3,7,9-tetrone IUPAC Name CAS-like Style 1 2.1.0 LexiChem openeye.com 2012.02.08 6a,9a-dichloro-2-ethyl-8-(4-fluorophenyl)-6-(4-hydroxy-3,5-dimethylphenyl)-3a,4,6,10,10a,10b-hexahydroisoindolo[5,6-e]isoindole-1,3,7,9-tetrone IUPAC Name Preferred 1 2.1.0 LexiChem openeye.com 2012.02.08 6a,9a-dichloro-2-ethyl-8-(4-fluorophenyl)-6-(4-hydroxy-3,5-dimethylphenyl)-3a,4,6,10,10a,10b-hexahydroisoindolo[5,6-e]isoindole-1,3,7,9-tetrone IUPAC Name Systematic 1 2.1.0 LexiChem openeye.com 2012.02.08 6a,9a-bis(chloranyl)-6-(3,5-dimethyl-4-oxidanyl-phenyl)-2-ethyl-8-(4-fluorophenyl)-3a,4,6,10,10a,10b-hexahydroisoindolo[5,6-e]isoindole-1,3,7,9-tetrone IUPAC Name Traditional 1 2.1.0 LexiChem openeye.com 2012.02.08 6a,9a-dichloro-2-ethyl-8-(4-fluorophenyl)-6-(4-hydroxy-3,5-dimethyl-phenyl)-3a,4,6,10,10a,10b-hexahydroisoindol[5,6-e]isoindole-1,3,7,9-diquinone InChI Standard 1 1.0.4 InChI nist.gov 2012.02.08 InChI=1S/C30H27Cl2FN2O5/c1-4-34-25(37)20-10-9-19-21(22(20)26(34)38)13-29(31)27(39)35(18-7-5-17(33)6-8-18)28(40)30(29,32)23(19)16-11-14(2)24(36)15(3)12-16/h5-9,11-12,20-23,36H,4,10,13H2,1-3H3 InChIKey Standard 1 1.0.4 InChI nist.gov 2012.02.08 HFQFLSNHSQPLDV-UHFFFAOYSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.02.08 4 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.02.08 584.128106 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.02.08 C30H27Cl2FN2O5 Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.02.08 585.450183 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.02.08 CCN1C(=O)C2CC=C3C(C2C1=O)CC4(C(=O)N(C(=O)C4(C3C5=CC(=C(C(=C5)C)O)C)Cl)C6=CC=C(C=C6)F)Cl SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.02.08 CCN1C(=O)C2CC=C3C(C2C1=O)CC4(C(=O)N(C(=O)C4(C3C5=CC(=C(C(=C5)C)O)C)Cl)C6=CC=C(C=C6)F)Cl Topological Polar Surface Area 7 E_TPSA 3.396 Cactvs xemistry.com 2012.02.08 95 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.02.08 584.128106 40 6 0 6 0 0 0 0 1 8