Bookmark and Share

Compound Summary for: CID 42611257

PLX4032

Also known as: Vemurafenib, Zelboraf, 918504-65-1, RG7204, PLX-4032, PLX 4032, 1029872-54-5, UNII-207SMY3FQT, RO5185426
Molecular Formula: C23H18ClF2N3O3S   Molecular Weight: 489.922126   InChIKey: GPXBXXGIAQBQNI-UHFFFAOYSA-N
Vemurafenib is a BRAF enzyme inhibitor developed by Plexxikon and Genentech for the treatment of late-stage melanoma. [Wikipedia] The cobas® 4800 BRAF B600 mutation test provided by Roche Molecular Systems is the diagnostic test to confirm eligibility for treatment. FDA approved on August 17, 2011 under the company Hoffmann La Roche.    From: DrugBank
Show subcontent titlesTable of Contents
Identification
Related Records
show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)
Use and Manufacturing
Pharmacology
Biomedical Effects and Toxicity
Safety and Handling
Environmental Fate and Exposure Potential
Exposure Standards and Regulations
Literature
Patents
Biomolecular Interactions and Pathways
Biological Test Results
Classification
Chemical and Physical Properties
_ _