4245792
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
16
16
8
8
8
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
4
4
5
6
6
6
7
7
8
9
9
9
9
10
10
10
11
11
11
12
12
12
13
13
13
14
14
18
18
18
20
20
20
21
21
21
16
17
17
18
15
19
20
19
15
16
33
8
16
17
10
11
15
22
12
23
24
13
25
26
14
27
28
14
29
30
31
32
19
34
35
21
36
37
38
39
40
1
1
1
1
2
1
1
2
1
1
1
1
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
0.1114
3.1383
-2.8277
6.2822
6.112
-2.1472
-0.0543
1.2992
-4.463
-4.9764
-5.3522
-6.4406
-6.8153
-7.3224
-3.0535
-0.7557
1.5231
4.1244
5.6009
7.7091
8.3077
-4.4869
-4.3701
-4.8649
-5.2846
-5.0068
-6.7927
-6.53
-6.9261
-7.4304
-8.352
-7.3454
-2.4912
3.9155
3.8686
8.0093
8.0591
8.0013
7.9523
9.3998
-1.8908
-1.5902
1.6924
0.7801
-1.4951
-0.5467
0.6428
0.3541
-0.003
-0.4083
1.0682
-0.8373
0.6354
0.2352
0.4988
-0.4366
-0.9312
-0.087
-0.3927
0.6685
2.0432
-0.8838
-1.2285
0.4294
2.0094
1.2888
-1.0528
-1.7681
-0.2113
1.4511
-0.1319
1.1186
-1.4943
0.6117
0.3668
0.0055
0.2529
2.7228
2.4795
1.9946
0.3637
0.2426
-0.0465
-0.1699
0.1528
0.2399
0.0196
0.0236
0.227
-1.1565
0.8626
-1.1115
0.903
-0.4793
0.1225
0.1863
0.1945
0.0099
0.0131
-0.1944
-0.4033
0.8834
-1.56
-1.8577
0.3013
1.8802
-2.1266
-0.538
1.5916
1.2994
-0.4024
-1.1294
0.3726
0.8262
-0.9527
-1.0135
0.7572
0.3988
-1.3426
-0.4272
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0040C92000000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
20.705
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
30.447
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10 15 17167863084735868152
10066227 49 16414929539501311686
10299344 5 18060137626362223782
10595046 47 18271243820272171690
106641 1 17458350761900289457
10968037 39 18411980261304189471
11315181 36 18344146995530426473
11524674 6 14620788315193854045
11638347 137 16298381345706459560
12091667 2 18202003223039230027
12236239 1 18202562852297350007
13073987 5 17023459737938781144
13288520 33 17561078108399735855
13533116 47 18336821979761923602
14123256 10 18409165510766839206
14251764 18 18342738520481267040
14251764 46 18333450936754751235
14344974 204 12174466267272385077
14428016 86 18407762543696007696
14729087 3 16588016905749188735
14849402 71 18341335573351086248
15183329 4 16988849367128821714
15419008 47 16443059504298321061
15716309 27 18343300336537052271
17093844 174 17095525081221402121
18681886 176 17774993622747738851
19489759 90 13623533437970385247
195137 175 18059861649334211393
20157964 124 18334295354113319874
20281389 69 18040714754153769540
20735858 18 13984661460544430896
21150785 3 17918275372409022382
21521721 280 18335704931560774570
220451 1 17560797706648352343
22224240 67 17530965795696751730
2297311 6 15913327983828200699
23035841 295 17703786994764494511
23081809 10 18272649009049156314
23402539 116 18131627864416692789
23559900 14 18335978778754604193
246663 6 12679466400089187924
28498 318 10519991452364401896
34797466 226 18131357388946153598
4073 2 18334862731276554450
4325135 7 18272368668122854645
4340502 62 16153429424407001010
445580 167 18341608239523244404
445580 37 16988570069658338873
5470011 282 14692574356157395536
5758199 1 18411139129865030426
59682541 35 17967821573806425105
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
407.32
24.89
1.63
0.85
20.4
0.04
0.08
-9.76
3.28
2.11
-0.07
-1.22
0.02
-1.37
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
801.286
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
244.3
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.02.08
1
69
124
36
114
162
33
50
58
52
139
174
186
44
23
118
194
146
203
206
145
239
209
20
190
7
41
236
187
102
90
218
82
61
219
2
168
210
182
88
29
87
16
228
34
171
48
12
227
63
175
176
111
101
188
169
121
193
144
205
163
4
108
154
223
54
8
65
177
45
137
167
165
37
153
53
86
110
238
164
72
89
56
136
230
226
135
81
73
11
156
96
207
79
179
180
80
123
232
160
166
142
70
185
71
19
85
202
83
42
143
125
130
134
28
126
103
149
117
75
198
66
217
178
184
213
107
140
235
46
201
215
199
3
183
62
18
181
21
113
192
127
106
189
237
51
74
211
10
159
68
6
109
233
105
38
84
212
224
157
93
128
14
216
151
30
196
27
97
155
161
112
26
43
104
9
77
220
15
141
35
173
22
76
131
132
92
25
170
197
49
100
234
40
147
129
120
222
229
55
24
31
195
191
99
17
221
200
122
57
13
214
32
208
116
119
231
94
172
204
225
60
5
95
115
91
59
150
67
39
47
78
138
158
148
98
133
152
64
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
16
1 -0.08
15 0.57
16 0.44
17 0.43
18 0.29
19 0.66
2 -0.29
20 0.28
3 -0.57
33 0.37
4 -0.43
5 -0.57
6 -0.49
7 -0.34
8 -0.34
9 0.06
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
9.2
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
6
1 3 acceptor
1 5 acceptor
1 6 donor
1 8 acceptor
5 1 7 8 16 17 rings
6 9 10 11 12 13 14 rings
21
0
0
0
0
0
0
0
1
3