4218614
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
17
17
8
8
8
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
3
4
4
5
6
6
6
7
7
7
7
8
8
8
9
9
9
10
10
11
11
12
12
12
13
14
14
15
16
16
17
17
18
18
19
20
20
19
21
13
14
15
15
10
11
13
8
9
12
22
10
23
24
11
25
26
27
28
29
30
31
32
33
14
34
35
16
17
18
19
36
20
37
21
21
38
1
1
2
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
2
1
2
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
6.1883
6.6514
-1.4245
0.322
1.181
-3.2712
-5.9987
-4.9544
-5.3079
-3.8744
-4.2229
-7.0304
-1.9072
-0.9894
1.3299
2.659
3.68
2.8319
4.9285
4.0804
5.1287
-6.5251
-5.4403
-4.4834
-4.8558
-6.0446
-3.1316
-4.3085
-4.6653
-3.7123
-7.5412
-6.5619
-7.7894
-1.105
-1.218
3.5178
2.0351
4.2197
1.5786
-1.5611
-1.7226
0.0665
2.1503
-0.4098
0.1799
1.2897
-1.136
0.8677
-1.5085
0.583
-0.6378
0.535
0.977
0.3603
1.1469
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0.5676
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0.0278
2.2061
1.5258
-1.0351
-1.9455
1.6629
0.7242
-1.7161
-2.4195
1.5065
0.7496
-0.1975
0.8869
1.326
2.2004
-1.6009
-2.6157
-1.0899
-0.4626
-0.05
0.3212
0.7901
0.4633
-0.3286
-0.1338
-0.7173
0.8611
0.2905
-1.3794
0.2852
0.5217
0.4861
0.2457
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0.5221
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0.296
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0.6231
0.2212
-1.0969
-1.7126
-0.7778
0.9445
1.8577
1.2719
-0.0371
-1.087
-2.3553
-1.497
1.5521
-0.2
-0.4601
0.9215
0.5153
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
00405EF600000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
43.6736
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
20.298
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10 15 9151172065199572885
10066227 112 18113616798385536773
10354089 29 10303810982670751170
106641 1 13829838120357593986
10835480 77 18335421322270322724
11315181 36 18060139851619338193
11719270 70 18412540999582159570
12107183 9 17689718562718342057
12166972 35 17203607112179744025
12236239 1 18413674612695663248
12516196 113 17989204845942062000
12616971 3 8214140733315198753
12670543 26 18408882932331660533
12838862 33 18340470215514672570
12916748 109 10737283537653014554
13533116 47 18060138700499849034
13668630 136 16415197901599754805
13782708 43 14979413759457200132
13862211 1 17917992771623508823
1420 363 12463569595230542965
14251752 14 18333727987978359534
14251764 18 18343025497558951865
14528608 73 18408886256404414434
146900 427 10953462933383275940
14848160 23 13758072996027298725
15048467 5 17749108915279145732
15183329 4 18409165485292415019
15188451 53 15698274517257020407
15196674 1 18411141346395248130
15475509 35 14404637450751719484
15716309 27 10375871875006153173
17349148 13 16845580837371184347
17834072 33 18341895211873275944
17834072 8 18410008823680294987
18006028 8 17917710180572466928
18222031 100 16988847189638548208
190975 80 10303516343656455285
19489759 90 16415200057763059947
20281389 69 16732977613856026221
20612939 158 18261117378758263624
20645477 70 18411421683437876622
21150785 3 17203609319750930220
21267235 1 18341902886943242091
220451 1 18273501182311137339
221357 26 18409441475654495613
2215653 11 18343579646776269351
22224240 67 15841544172813183838
23081809 10 18059863843735250568
23198884 109 18040715866391939637
23402539 116 17561083592777859897
23522609 53 18056510358930367080
23559900 14 18271799190019961017
2871803 45 18333452028388600994
29717793 49 18342743992570276174
300161 21 18187080676210867936
3004659 81 18335139770194885674
3014965 18 18115019710597674106
3663271 9 9583520919002856997
4073 2 17749397008874546874
4214541 1 18411702084445598377
465052 167 18060706117050317006
542803 24 12684811121458104618
559249 180 18272368651001410223
59755656 215 18409726223659841663
6138700 20 18342177717764100006
6328613 192 18333735727573256781
960060 61 18335425681556158980
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
413.32
19.21
1.83
0.95
5.58
0.02
-0.14
0.49
-7.26
-1.31
-0.02
0.44
-0.19
-0.33
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
842.44
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
240.6
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.02.08
1
116
217
36
280
20
262
25
244
132
266
160
304
81
287
173
50
130
225
45
108
49
46
174
63
247
39
306
246
127
161
264
194
6
269
249
298
23
305
10
40
198
33
238
164
66
191
312
13
240
183
104
281
169
224
206
2
35
232
34
237
27
278
211
112
98
91
86
228
179
93
213
32
21
87
12
310
70
99
117
56
55
140
48
250
222
11
95
201
133
149
111
3
139
53
297
296
103
137
65
77
229
4
96
219
105
209
145
120
71
100
19
134
286
5
147
162
151
207
69
18
279
82
284
26
168
212
152
8
185
123
265
119
110
155
186
16
51
195
295
197
37
301
234
167
60
24
76
223
260
216
124
193
253
239
54
92
113
90
275
42
288
221
256
154
258
58
146
14
143
38
293
176
64
235
299
84
85
29
259
43
215
17
187
272
245
307
165
153
80
273
128
158
9
230
226
142
291
271
203
204
148
121
7
125
44
68
231
210
182
180
122
236
188
308
72
59
302
79
94
101
285
118
73
192
156
135
31
67
282
309
268
220
205
257
22
141
144
41
172
74
129
115
252
181
47
61
177
97
109
202
138
126
233
150
52
303
102
189
289
136
254
248
242
175
283
292
255
88
83
208
30
184
263
267
89
170
166
190
107
157
57
261
106
277
171
251
28
131
199
241
163
227
196
243
78
178
75
159
290
214
62
294
218
270
200
276
300
274
311
114
15
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
20
1 -0.18
10 0.3
11 0.3
13 0.57
14 0.34
15 0.63
16 0.09
17 -0.15
18 -0.15
19 0.18
2 -0.18
20 -0.15
21 0.18
3 -0.57
36 0.15
37 0.15
38 0.15
4 -0.43
5 -0.57
6 -0.66
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
6.2
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
4
1 3 acceptor
1 5 acceptor
6 16 17 18 19 20 21 rings
6 6 7 8 9 10 11 rings
21
0
0
0
0
0
0
0
1
1