NSC305352 - PubChem

NSC305352 - Compound Summary (CID 41987) Also known as: Prestwick0_000092, Prestwick1_000092, SureCN145093, AC1L26VA, NCIStruc1_001846, NCIStruc2_001359 Molecular Formula: C₁₆H₁₇BrN₂ Molecular Weight: 317.22358 InChIKey: OYPPVKRFBIWMSX-UHFFFAOYSA-N Zimelidine has been banned worldwide due to serious, sometimes fatal, cases of central and/or peripheral neuropathy known as Guillain-Barr� syndrome and due to a peculiar hypersensitivity reaction involving many organs including skin exanthema, flu-like symptoms, arthralgias, and sometimes eosinophilia. Additionally, zimelidine was charged to cause an increase in suicidal ideation and/or attempts among depressive patients. After its ban, it was succeeded by fluvoxamine and fluoxetine (derived from the antihistamine diphenhydramine) in that order, and the other SSRIs. From: DrugBank View the conformer with web-based 3D viewer View the conformer with Pc3D viewer application Download Pc3D viewer application 2D ASN.1 Text: Display 2D ASN.1 Text: Save 2D ASN.1 Binary: Save 3D ASN.1 Text: Display 3D ASN.1 Text: Save 3D ASN.1 Binary: Save 2D XML: Display 2D XML: Save 3D XML: Display 3D XML: Save 2D SDF: Display 2D SDF: Save 3D SDF: Display 3D SDF: Save BioActivity, this compound BioActivity, with similar compounds BioActivity, with similar conformers
Show subcontent titlesHide subcontent titlesTable of Contents Identification Depositor-Supplied Synonyms Compound Information Related Records Related Compounds with Annotation Related Compounds Related Substances Use and Manufacturing Methods of Manufacturing Pharmacology Therapeutic Uses Drug Warning Minimum/Potential Fatal Human Dose Biomedical Effects and Toxicity Absorption, Distribution and Excretion Metabolism/Metabolites Biological Half-Life Interactions Antidote and Emergency Treatment Human Toxicity Excerpts Non-Human Toxicity Excerpts Non-Human Toxicity Values Safety and Handling Decomposition Disposal Methods Literature Depositor Provided PubMed Citations Patents Depositor-Supplied Patent Identifiers Biomolecular Interactions and Pathways Interactions Target Transporter Action General Function Specific Function Gene Name GenBank Gene GenBank Protein References Biological Test Results BioAssay Results Classification Ontologies Substance Categorization Classification Chemical and Physical Properties Dissociation Constants Octanol/Water Partition Coefficient Solubilities Vapor Pressure Other Chemical/Physical Properties Computed Properties Expand all sub-sections	2D Structure 3D Conformer
Identification Help top of page Related Records Help top of page show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)show first sub-section only Use and Manufacturing Help top of page Pharmacology Help top of page show all 3 sub-sections (Therapeutic Uses, Drug Warning, Minimum/Potential Fatal Human Dose)show first sub-section only Biomedical Effects and Toxicity Help top of page show all 8 sub-sections (Absorption, Distribution and Excretion, Metabolism/Metabolites, Biological Half-Life ...)show first sub-section only Safety and Handling Help top of page show all 2 sub-sections (Decomposition, Disposal Methods)show first sub-section only Literature Help top of page Patents Help top of page Biomolecular Interactions and Pathways Help top of page Biological Test Results Help top of page Data Analysis Data Download BioActivity Summary: This Compound with Similar Compounds with Similar Conformers Classification Help top of page show all 2 sub-sections (Ontologies, Substance Categorization Classification)show first sub-section only Chemical and Physical Properties Help top of page show all 6 sub-sections (Dissociation Constants, Octanol/Water Partition Coefficient, Solubilities, Vapor Pressure ...)show first sub-section only

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