416492
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
17
16
8
8
8
8
7
7
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
3
4
4
5
6
7
7
7
8
8
8
9
9
9
10
10
10
11
11
13
13
13
14
14
16
16
16
17
17
17
18
18
19
19
19
20
20
20
18
11
19
12
17
14
15
12
15
9
15
26
13
16
31
10
12
21
11
22
23
24
25
14
27
28
29
30
18
32
33
20
34
35
36
37
38
39
40
41
42
43
1
1
1
1
1
1
1
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
9
7
10
12
21
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
-8.4684
3.91
2.8087
-1.1043
4.5471
-0.0977
1.1383
-4.7862
2.4553
3.0391
3.2159
3.395
-3.461
-2.3871
-0.0271
-5.8226
3.6297
-7.1956
2.3794
2.8317
2.37
2.3745
4.0087
2.276
3.9231
1.0562
-3.2906
-3.3554
-2.5183
-2.4354
-4.9162
-5.687
-5.7535
4.5133
3.946
-7.3742
-7.311
2.5976
1.9551
1.6489
1.9345
2.4926
3.4304
-0.4686
3.1737
-1.908
-0.0516
-1.1229
0.7906
-0.1054
0.1602
0.0878
1.4443
1.5553
-1.0368
-0.1388
0.2761
0.262
-0.2726
-2.9939
0.0742
4.1339
-3.8594
0.0437
2.2369
1.5844
1.4015
0.8004
-0.5291
0.3854
-1.2105
-0.2576
1.3564
-0.3007
0.2232
-1.3552
-2.5976
-3.5884
-0.4164
1.1545
5.1626
4.1549
3.7209
-4.248
-3.2737
-4.7012
-1.1255
-1.3932
-0.3012
0.2931
0.9804
2.178
0.4306
0.3676
0.9843
0.5681
-0.9465
0.5673
-0.1541
0.839
1.0734
-0.5607
-0.7437
-0.0061
-1.3554
-1.6954
2.0766
0.9329
1.0637
-1.4856
-1.3042
-0.489
-1.1027
-0.3656
1.7883
1.0226
1.2678
-1.5298
-0.7242
-1.2563
0.1207
0.956
0.1276
-1.6548
-0.349
-2.0559
-1.2023
-2.5563
-2.0543
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
00065AEC00000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
16.4053
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
30.446
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
11796584 16 15984814987319037327
13533116 47 17988922250126761891
13836976 161 18341614832667379998
14863182 85 17775003462787170542
15183329 4 17060625495523726553
15475509 35 12391527359690133229
17844677 252 18114180805402026829
20645477 70 18412261705446327251
21304303 282 17477759552451526004
21304303 94 17632312193565988006
220451 1 17917997213658935943
23081809 10 18060423513277760401
23522609 53 17916048861933287993
23559900 14 18412543240694738778
239999 70 18333167271445265106
29717793 49 18408600341080177809
3004659 81 18342173345492440299
3060560 45 18338812203682968620
34797466 226 18113898278300415781
46194498 28 18333730199886614877
5281201 14 18260829250460538693
59682541 52 18411696583003877413
60123966 16 18187081767275083709
6025842 7 18411140259683924822
7164475 11 18199756847057707184
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
383.87
16.87
3.96
1.56
52.3
0.2
-0.04
-1.09
6.13
-10.38
3.5
-0.93
0.05
-0.81
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
701.325
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
246.3
Conformer
RMSD
7
2009.12.11
1
Diverse Conformer
ID List
6
2012.02.08
1
65
137
83
125
109
94
154
32
153
207
59
134
66
174
181
70
178
26
184
23
122
19
105
160
156
81
58
9
119
104
110
51
131
12
93
203
143
43
149
22
204
177
186
195
101
44
40
138
115
20
193
201
169
132
68
151
162
126
175
202
6
187
150
205
188
118
170
198
29
200
33
21
168
183
103
167
159
85
27
176
155
82
28
194
208
189
76
10
77
136
56
80
147
62
152
72
107
78
163
41
171
145
69
57
144
74
192
13
172
63
206
97
141
91
67
190
36
165
46
98
182
96
120
55
99
166
16
124
100
179
54
88
116
180
24
142
47
139
128
5
61
164
157
135
191
4
113
42
158
129
48
53
185
11
108
112
197
121
196
25
87
34
140
148
14
7
15
64
89
84
45
130
79
161
173
31
38
92
127
18
133
17
60
199
90
73
146
8
35
102
39
71
37
49
52
2
117
50
111
75
123
106
30
86
95
114
3
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
20
1 -0.29
11 0.23
12 0.66
13 0.27
14 0.28
15 0.78
16 0.27
17 0.28
18 0.29
19 0.23
2 -0.46
26 0.37
3 -0.43
31 0.36
4 -0.43
5 -0.57
6 -0.57
7 -0.73
8 -0.9
9 0.36
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
14
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
6
1 19 hydrophobe
1 5 acceptor
1 6 acceptor
1 7 donor
1 8 cation
1 8 donor
20
1
0
1
0
0
0
0
1
2