4115974
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
17
16
16
8
8
8
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
3
4
4
5
6
7
7
7
8
8
8
9
9
10
10
10
11
11
11
12
12
12
13
13
14
14
15
16
16
18
18
19
20
21
22
22
23
23
24
24
25
26
26
27
27
28
16
17
20
25
10
13
15
19
14
15
38
17
18
19
17
21
11
14
29
12
30
31
13
32
33
34
35
36
37
16
39
40
23
24
20
21
22
25
41
26
42
27
43
44
28
45
28
46
1
1
1
1
1
1
1
2
2
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
2
1
2
1
1
1
2
1
1
2
1
1
1
10
4
11
14
29
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
-6.0892
-1.189
2.6836
2.6271
-1.1583
-0.2271
1.1503
-0.6417
1.0971
1.6053
1.9805
2.6202
3.3658
1.5103
-0.1642
-0.2773
-0.1162
-1.9608
0.1441
1.4734
1.9138
3.2646
-3.0265
-2.1506
3.8123
-4.3071
-3.4311
-4.5093
0.6729
1.1197
2.7195
1.8436
3.2714
4.3661
3.4648
2.4796
0.7737
1.9056
-0.8311
0.7005
3.8127
-2.8777
-1.3244
4.8188
-5.1378
-3.5731
0.5672
-0.4622
-2.7956
1.3294
2.4392
-2.0058
2.2109
-1.2105
-1.2966
2.337
3.2214
2.2243
1.3266
3.0867
1.9546
1.0126
-1.0225
-0.7801
-1.8056
-2.1052
-1.8474
-2.2153
-1.6616
0.5112
-2.7496
-1.2436
0.929
0.0516
1.8121
3.7353
3.9763
1.6507
2.6784
1.7184
0.3039
3.5213
3.8941
1.7498
1.5219
0.7342
-2.1038
-2.6725
1.2003
-3.1166
-1.9382
1.9404
-1.389
2.7489
-1.3804
-0.5936
1.5505
-2.0267
1.7139
0.1522
1.8492
-0.6792
-1.8556
-2.7888
-1.8244
0.6354
2.0888
3.2642
1.461
-0.2208
-0.8721
-0.4105
0.8572
1.0648
-0.1032
-0.6937
-0.0843
-0.4656
-1.056
-0.9421
-0.8954
-2.2922
-1.561
-3.3087
-3.5401
-1.6115
-2.1962
0.903
0.5648
2.2124
4.059
3.6674
1.9913
0.2662
-0.8026
-0.2275
-0.3715
-1.4283
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
003ECE0600000002
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
79.5414
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
40.68
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10190108 129 17403465560058146263
10305334 12 12688215385878790566
11112662 9 16444746279836715597
11578080 2 17171562953826289065
12035759 4 18059033738104569000
12156800 1 16915114918731818057
12166972 35 18339637824449927439
12422481 6 17903592472688897872
12539773 59 13536065169992306604
12633257 1 15648435944298254472
133893 2 18118148959608507948
14114207 22 17982696888620853584
14468879 13 17316494095188350236
15163728 17 17169565205322403645
15238133 3 17632303311958351425
17357779 13 17343475853094294515
18365409 1 17338712666103457497
18769570 83 17826781547627660656
20600515 1 17904175067263236135
20691752 17 16660638544920372599
229495 10 18045807803013417411
23419403 2 17550335789143291208
23559900 14 18263626443050276767
238 59 18189631590579752012
35225 105 17040974103866289596
44802255 64 17176053527356278908
469060 322 17900821544631321658
6669772 16 17628623456566762992
9925002 15 17770518451118653512
9981440 41 17607534818923802772
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
553.24
7.5
4.03
2.88
10.11
1.72
-1.69
-1.36
5.24
-4.8
0.96
-0.49
1.29
-0.95
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1161.205
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
314.7
Conformer
RMSD
7
2009.12.11
1
Diverse Conformer
ID List
6
2012.02.08
2
25
99
105
103
8
178
111
73
106
1
183
114
139
175
64
169
135
39
164
55
71
185
126
193
112
110
30
147
170
141
130
159
128
113
174
132
15
179
187
137
74
3
123
167
180
151
192
134
119
156
148
45
89
153
50
154
115
157
94
120
121
67
108
76
146
42
162
47
104
21
144
93
79
19
57
124
5
116
98
101
189
13
163
38
28
172
66
81
107
117
152
40
51
125
109
188
56
131
7
22
59
72
31
4
68
149
85
133
173
60
82
171
122
34
20
97
29
58
63
181
35
36
69
10
77
24
158
142
70
100
49
44
37
184
145
127
90
155
182
41
129
12
26
62
186
87
168
78
52
102
165
177
92
143
11
80
161
23
9
18
61
118
6
166
138
48
65
83
140
46
95
33
14
136
27
150
160
17
96
91
190
191
75
16
43
88
84
176
53
86
32
54
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
33
1 -0.18
10 0.28
13 0.28
14 0.3
15 0.57
16 0.29
17 0.65
18 0.12
19 0.71
2 -0.37
20 -0.05
21 0.12
22 -0.15
23 -0.15
24 -0.15
25 -0.11
26 -0.15
27 -0.15
28 0.18
3 -0.08
38 0.37
4 -0.56
41 0.15
42 0.15
43 0.15
44 0.15
45 0.15
46 0.15
5 -0.57
6 -0.57
7 -0.73
8 -0.24
9 -0.57
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
8
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
8
1 4 acceptor
1 5 acceptor
1 6 acceptor
1 7 donor
5 3 20 21 22 25 rings
5 4 10 11 12 13 rings
6 18 23 24 26 27 28 rings
6 8 9 17 19 20 21 rings
28
1
0
1
0
0
0
0
1
2