4111671 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 8 8 8 8 8 8 7 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 -1 3 -1 5 -1 7 1 10 1 11 1 12 1 1 2 3 4 5 6 7 7 7 8 8 9 9 10 11 12 13 13 13 14 14 15 15 16 17 17 18 18 19 19 20 20 20 21 21 21 22 23 23 24 24 25 25 26 26 27 27 29 30 30 31 31 32 33 10 10 11 11 12 12 13 14 15 9 16 25 47 28 29 32 16 34 35 18 20 19 21 17 23 24 22 36 22 37 38 39 40 41 42 43 44 26 45 27 46 29 30 28 48 28 49 31 33 50 32 51 33 52 1 2 1 2 1 2 1 2 1 1 2 1 1 1 1 1 1 1 1 1 1 2 1 1 2 1 2 1 1 1 1 1 1 1 1 1 1 1 1 2 1 2 1 2 1 1 1 1 2 1 2 1 1 1 8 -1 9 16 13 17 3 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 -5.6203 -5.7253 4.9246 2.7453 6.8391 7.7245 -2.1819 0.5104 1.5911 -5.1898 3.8879 6.7278 -0.9241 -3.3022 -2.1403 -0.6896 -1.8453 -4.4973 -3.3053 -3.2715 -0.85 -4.4941 -2.3416 -2.4572 2.8815 -3.4498 -3.5655 -4.0618 4.0124 3.0396 5.2841 5.4335 4.3112 -0.8754 -0.1202 -5.4238 -3.3057 -3.4431 -4.1033 -2.3798 -0.3404 -0.1932 -1.0195 -5.4179 -1.8605 -2.076 1.5084 -3.806 -4.0156 2.1909 6.1619 4.39 3.8593 3.3247 -2.8308 -2.6155 2.9848 0.9862 -2.1442 0.3617 -0.4216 3.2286 -2.1265 1.748 -1.6203 -2.0272 -2.7115 -0.1526 0.7152 -2.5104 -3.213 -1.3813 -2.8076 -3.1092 1.426 0.8371 0.1015 2.2588 1.67 2.3808 -0.7233 1.4773 -0.1792 1.1931 2.0213 -1.7629 -2.2656 -2.429 -3.6814 -2.1585 -0.6715 -0.8513 -1.8426 -3.5547 -3.1276 -3.4947 1.36 0.2949 -1.3568 2.8008 1.7412 2.1561 -0.8211 3.0946 0.7556 -1.371 0.4099 0.5635 -0.5433 -0.3421 0.1962 0.2156 0.3597 -0.2402 0.4011 -0.3643 0.7697 0.9115 -1.0109 0.3884 0.227 0.3981 -1.5738 2.2552 -1.7524 -0.8581 1.3196 -1.0206 0.1811 1.1649 -1.1755 -0.0827 0.2003 -0.0209 0.02 -0.1806 -0.2011 1.8507 0.4182 0.9579 -2.5529 3.0101 2.3358 2.5718 -1.8177 -1.2959 -2.7872 -1.2791 2.2921 -1.8818 0.7269 2.0372 -2.1624 -0.0402 0.0349 -0.3542 Conformer ID 11 2.1 PubChem ncbi.nlm.nih.gov 2009.12.11 003EBD3700000001 Energy MMFF94 NoEstat 7 1.7.2 Szybki openeye.com 2012.11.26 143.8014 Feature Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 71.296 Fingerprint Shape 2 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 10050765 1 18409167693106623946 10076449 9 18267300010452040543 11101153 10 18046068430419436996 12107183 9 18121494657702079394 12422481 6 18194712340040103155 12788726 201 18265319776519086611 13540713 5 18189598510605008234 13631057 29 18269551813690170318 14118638 360 18334572486503450530 144659 39 18340214011481817039 14790565 3 17978793411356821745 14840074 17 18197785602950135398 15276724 80 18411135879255269063 15439362 3 18054232020597525397 15575132 122 18342459287272257070 16114785 44 18260837007836250683 19427546 20 18411418453300281541 21033648 144 18261949652693321828 21236236 1 18336547213133179880 22393880 68 18271807960669895228 22907989 373 18201145607916742583 23559900 14 17974846482540191728 249057 3 18194118521771700282 283562 15 18261951959692406123 32027 91 17700997456993811558 350125 39 18340208595348546331 4073 2 18113624495325211618 4409770 3 18343298206750140967 484985 159 14764347193372657965 5104073 3 18113053823041678458 5171179 24 17771894189990646321 563151 97 18334013934675622650 6036956 94 17900830658198691116 6327066 14 18336262332764966101 6371009 1 18046058539658237460 6898599 12 18412825802187450821 7237137 82 18340770441516562389 Shape Multipoles 8 1.8.3 OEShape openeye.com 2012.11.26 614.02 16.06 4.89 1.34 27.21 0.77 0.08 9.93 -2.02 -7.12 -1.02 -1.87 -0.43 -1.05 Shape Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 1334.085 Shape Volume 7 1.8.3 OEShape openeye.com 2012.11.26 334.2 Conformer RMSD 7 2009.12.11 1 Diverse Conformer ID List 6 2012.02.08 1 10 8 11 5 3 2 9 4 6 7 Charge MMFF94 Partial 2 1.7.6 OEChem openeye.com 2012.02.08 44 1 -0.52 10 0.91 11 0.91 12 0.91 13 0.55 14 0.22 15 0.22 16 0.3 17 0.09 18 -0.15 19 -0.15 2 -0.52 20 0.14 21 0.14 22 -0.15 23 -0.15 24 -0.15 25 0.1 26 -0.15 27 -0.15 28 0.13 29 0.13 3 -0.52 30 -0.15 31 -0.15 32 0.13 33 -0.15 36 0.15 37 0.15 4 -0.52 44 0.15 45 0.15 46 0.15 47 0.4 48 0.15 49 0.15 5 -0.52 50 0.15 51 0.15 52 0.15 6 -0.52 7 -0.21 8 -0.49 9 -0.46 Count Effective Rotor 7 1.7.6 OEChem ncbi.nlm.nih.gov 2012.01.18 8 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.1 OEShape openeye.com 2012.02.08 14 1 1 acceptor 1 1 anion 1 2 acceptor 1 3 acceptor 1 3 anion 1 4 acceptor 1 5 acceptor 1 5 anion 1 6 acceptor 1 8 acceptor 1 9 donor 6 17 23 24 26 27 28 rings 6 25 29 30 31 32 33 rings 6 7 14 15 18 19 22 rings 33 0 0 0 1 0 1 0 1 1