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Compound Summary for: CID 3749


Also known as: Avapro; Aprovel; 138402-11-6; Karvea; BMS-186295; SR-47436; Irbesarran; Lrbesartan; Irbetan
Molecular Formula: C25H28N6O   Molecular Weight: 428.52942   InChIKey: YOSHYTLCDANDAN-UHFFFAOYSA-N
Irbesartan is an angiotensin receptor blocker (ARB) used mainly for the treatment of hypertension. It competes with angiotensin II for binding at the AT1 receptor subtype. Unlike ACE inhibitors, ARBs do not have the adverse effect of dry cough. The use of ARBs is pending revision due to findings from several clinical trials suggesting that this class of drugs may be associated with a small increased risk of cancer.   From: DrugBank
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