ibudilast - Compound Summary (CID 3671) Also known as: Ketas, Ke Tas, Eyevinal, Ibudilastum, Ibudilastum [Latin], 50847-11-5, KC-404, Ketas (TN), Tocris-1694 Molecular Formula: C 14H 18N 2O Molecular Weight: 230.30552 InChIKey: ZJVFLBOZORBYFE-UHFFFAOYSA-N Ibudilast is an anti-inflammatory and neuroprotective oral agent which shows an excellent safety profile at 60 mg/day and provides significantly prolonged time-to-first relapse and attenuated brain volume shrinkage in patients with relapsing-remitting (RR) and/or secondary progressive (SP) multiple sclerosis (MS). Ibudilast is currently in development in the U.S. (codes: AV-411 or MN-166), but is approved for use as an antiinflammatory in Japan. From: DrugBank |
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