3544296
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
17
17
8
8
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
3
4
5
5
5
6
6
7
7
7
8
8
8
9
9
10
10
11
11
12
12
13
13
14
14
15
17
17
18
19
19
21
21
22
22
23
24
24
23
25
16
20
6
16
33
20
34
19
20
35
9
10
11
12
14
13
16
17
26
15
27
15
28
18
29
30
18
31
32
21
22
23
36
24
37
25
25
38
1
1
2
2
1
1
1
1
1
1
1
1
1
1
2
1
2
2
1
1
1
2
1
1
1
1
1
1
2
1
1
2
1
1
1
2
1
2
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
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32
33
34
35
36
37
38
7.5451
7.8927
-1.9062
1.1706
-0.9713
0.3109
2.5631
-3.9999
-5.293
-3.3781
-3.3668
-5.9261
-4.0218
-5.9147
-5.2933
-2.0458
-3.9992
-5.2705
3.8439
1.3456
4.9404
3.9768
6.2038
5.2402
6.3536
-2.3744
-6.9201
-3.5419
-6.9084
-5.7941
-3.4988
-5.7624
-1.0825
0.4563
2.5295
4.8165
3.1658
5.3402
-0.9938
1.5717
-1.7684
0.528
-0.9894
-1.2326
-0.8276
0.2597
0.4811
-0.9833
1.2876
-0.5471
-1.9935
1.7242
-1.7757
-1.2859
2.5165
2.7344
-0.2646
-0.4133
-0.8226
0.8338
-0.2671
1.3892
0.8388
1.1594
-0.3993
-2.9564
1.9167
-2.5625
3.3035
3.6913
-0.599
-2.0229
-1.631
-1.685
1.3158
2.2511
-1.2703
0.67
-1.6742
1.0902
0.2964
-0.1316
-0.2266
-0.2255
0.3052
-0.0237
-0.9432
1.0224
0.6916
0.1033
1.2136
-0.5391
-1.1341
-0.6117
-0.0219
0.3196
-0.6592
0.8122
-0.4572
1.0143
0.3795
-1.3688
1.4395
0.849
0.5024
1.7704
-1.6909
-0.7607
1.2268
-0.7506
-0.8492
-1.3102
1.3376
1.6695
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
003614E800000002
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
77.747
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
42.215
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10 15 18334574659129012241
10066227 112 18131348626928377232
10165383 225 17988929977289846787
10411042 1 17972890430745445771
10638233 991 16732993058916937372
11089746 13 14333407848466467522
11135926 11 16917075434311856302
11497681 19 17488170690547782551
13073987 5 18040992934490001746
13403585 85 18334576854368918633
13911987 19 17489583429776220967
14251752 14 18410573951451264754
14251764 18 15864072096508388454
14598715 104 18271229600126435920
14849402 71 17168997845166174348
14856354 85 17603592958201308747
14933364 13 18410295822074586658
15119646 104 14979684243627976518
15183329 4 17275103916637795114
15461852 350 18273492399514467839
15716309 27 13623526865937316218
16110190 28 18334016120429420045
17844677 252 18261960738230460184
19377110 9 16515678931745540568
20281389 69 18410573981136123808
21033648 29 18272638073967261168
21756936 100 18335132116120325347
21792961 116 18272375226733399450
22956985 138 17104547922773714731
23081809 10 16950278508111695250
23198884 109 15554443007644902917
23522609 53 16661228974153617212
23559900 14 17060048298662728826
29717793 49 16128665146048139462
3663271 9 17676481748764458354
4073 2 18187088390563540762
4098825 35 18187931630035128322
445580 37 18260840280136885164
4938544 92 17313377890984523413
504843 32 17131827720100603998
5104073 3 18040710320988170826
9995097 60 18342739615502774726
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
491.55
22.85
2.35
1.18
28.59
0.95
-0.12
6.35
1.25
-3.68
-0.3
0.16
-0.08
2.99
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1055.644
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
271.5
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.02.08
2
30
10
21
33
44
20
7
56
29
52
25
54
41
57
15
58
26
51
60
11
32
1
47
22
53
45
14
34
59
42
13
9
27
31
39
55
23
12
3
8
43
49
19
48
46
17
50
28
40
4
16
24
18
36
38
6
35
37
5
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
36
1 -0.18
10 0.09
11 -0.15
12 -0.15
13 -0.15
14 -0.15
15 -0.15
16 0.54
17 -0.15
18 -0.15
19 0.12
2 -0.18
20 0.69
21 -0.15
22 -0.15
23 0.18
24 -0.15
25 0.18
26 0.15
27 0.15
28 0.15
29 0.15
3 -0.57
30 0.15
31 0.15
32 0.15
33 0.37
34 0.37
35 0.37
36 0.15
37 0.15
38 0.15
4 -0.57
5 -0.43
6 -0.43
7 -0.55
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
6
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
8
1 3 acceptor
1 4 acceptor
1 5 donor
1 6 donor
1 7 donor
6 19 21 22 23 24 25 rings
6 8 9 10 12 13 15 rings
6 8 9 11 14 17 18 rings
25
0
0
0
0
0
0
0
1
6