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Compound Summary for: CID 3448

gaboxadol

Also known as: THIP; Gaboxadolum [Latin]; Gaboxadolum; 4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3-ol; UNII-K1M5RVL18S; Prestwick-13B03; CHEMBL312443
Molecular Formula: C6H8N2O2   Molecular Weight: 140.13992   InChIKey: ZXRVKCBLGJOCEE-UHFFFAOYSA-N
Gaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep aid drug developed by Lundbeck and Merck. In March, 2007, Merck and H. Lundbeck cancelled work on the drug, citing safety concerns and the failure of an efficacy trial. It acts on the GABA system, but possibly in a different way from benzodiazepines, nonbenzodiazepines and barbiturates - (Valium, Sodium Pentothal, Ambien etc.). Lundbeck states that gaboxadol also increases deep sleep (stage 4). It is, however, not reinforcing like benzodiazepines are. [Wikipedia]   From: DrugBank
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