33338
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
8
8
8
8
8
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
3
4
4
5
6
6
6
7
7
7
8
8
9
9
9
10
10
11
11
12
12
12
13
14
14
15
15
15
16
16
16
17
17
19
19
19
20
20
20
21
21
21
8
33
14
18
15
45
17
46
18
7
9
12
8
11
22
10
23
10
24
25
26
27
13
14
13
28
29
30
31
32
16
17
18
19
20
34
21
35
36
37
38
39
40
41
42
43
44
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
7
6
8
11
22
3
1
8
1
10
7
23
2
1
15
3
16
17
18
3
1
17
4
15
21
35
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
-1.8131
0.5383
3.9934
1.972
1.9474
-3.6356
-2.3553
-2.7254
-4.7252
-4.1148
-1.7947
-3.6865
-2.5454
-0.5485
2.8233
2.4772
3.1488
1.7429
3.4984
2.2234
3.5794
-1.6679
-2.7563
-5.0148
-5.6102
-4.0643
-4.6751
-3.5507
-4.6378
-2.3473
-0.2974
-0.6913
-0.9314
1.5291
3.9532
4.4959
3.213
3.5623
1.8365
3.1418
1.4809
4.4755
3.796
2.7817
3.7674
1.8123
-2.4164
0.494
-0.3086
1.3124
0.5624
0.3707
-0.1255
-1.3581
-0.3612
-1.7221
1.0239
1.823
2.1136
0.9137
-0.089
-1.461
1.0431
0.3562
-1.9617
-2.5639
2.3545
-0.3818
-1.1489
0.096
-0.425
-2.3252
-2.2974
2.3717
2.1426
3.085
1.8817
0.1843
-2.1049
-1.3421
0.744
-2.0503
-2.947
-1.29
-3.4645
-2.8505
-2.2624
2.2263
3.1025
2.778
-0.9081
0.5433
-0.2435
-0.4008
-0.8372
1.7471
-2.2168
0.9425
0.35
-0.4775
0.279
0.0169
-0.4315
0.6675
-0.2486
-1.2318
-0.0325
0.6205
0.9752
-1.026
1.646
-0.4208
0.3223
1.166
-1.5537
-0.6762
0.9188
0.9321
-0.7267
1.6058
0.228
-0.6778
-1.6823
-2.0374
-0.5102
1.1629
1.6555
1.2036
2.0306
2.507
0.0699
-0.9431
-1.1653
-0.2915
1.0934
-0.2969
-1.5673
2.3192
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0000823A00000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
39.7097
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
56.196
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10366900 7 17986946534767954265
10616163 171 18410018766329638511
11552529 35 17417810707717955151
11578080 2 17750776922112224029
12363563 72 15719382936807260868
12500047 106 18338795602753550709
12553582 1 18187939433810902677
12633257 1 18272087132847777449
13224815 77 18114177544825159721
13533116 47 18341609275048400775
13583140 156 18271230651997628237
14081887 123 18199176476774442035
14178342 30 18335979860753760696
14223421 5 18412823590242155501
14289901 80 18410291436533637289
14866123 147 16039160152612077798
17804303 29 18266181617076983686
1813 80 17167865274905497509
19862831 5 11312058746719819033
20442098 301 18334013865243859567
2255824 54 17751095805805286884
22646028 28 18113339704333249487
23559900 14 18130234756734288069
339767 52 18041271175382354507
3797600 57 17631451340100871192
5104073 3 18408608033134659633
6442390 28 18197214965653340344
7064713 232 18268423542971930115
7097593 13 18336543837246674244
8988823 20 18271794766314155741
90316 7 18334583412921825045
9709674 26 18411423903561643175
9882013 296 18200311151225870485
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
397.84
8.99
2.65
1.37
3.35
0.61
-0.11
0.7
2.07
-0.53
0.3
-1.11
-0.16
-0.4
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
816.386
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
232.4
Conformer
RMSD
7
2009.12.11
1
Diverse Conformer
ID List
6
2012.02.08
1
6
288
320
35
372
95
265
330
105
326
76
62
355
284
178
348
295
167
234
229
276
252
40
106
315
333
196
102
267
226
262
131
366
248
195
281
291
345
270
301
317
31
296
186
30
237
171
153
264
120
217
361
128
253
111
199
298
77
304
338
319
78
58
335
233
14
286
279
352
83
300
94
137
369
86
259
343
354
206
146
293
329
158
373
61
261
75
118
213
219
274
257
166
65
321
241
308
121
73
89
126
29
46
263
292
339
350
41
358
81
114
93
51
159
242
221
28
181
74
258
363
152
205
285
148
55
172
49
337
283
174
347
97
269
202
207
115
21
260
184
188
256
134
371
143
273
37
324
208
251
107
341
85
332
26
302
222
160
244
192
340
289
211
310
82
277
223
232
39
275
20
346
66
44
24
362
309
157
306
278
16
54
218
191
282
135
290
303
169
25
84
170
147
88
133
116
67
8
12
230
142
336
22
156
227
255
312
13
110
9
173
141
243
311
356
357
123
316
43
351
182
287
50
307
246
68
139
34
175
161
56
47
15
151
57
349
190
80
109
96
203
180
149
325
334
101
163
144
69
212
38
45
271
154
19
112
280
136
168
164
189
150
214
42
162
17
2
113
250
238
79
72
3
27
32
359
215
140
60
193
318
210
99
322
23
370
368
108
127
365
132
353
100
266
4
228
367
18
104
138
130
299
87
177
323
48
183
327
103
231
185
328
364
198
64
216
70
360
239
33
53
52
268
297
249
235
224
197
5
272
331
36
247
63
342
314
59
11
117
305
122
201
200
7
204
194
254
90
145
10
294
91
236
176
119
124
313
245
165
240
92
179
98
225
209
125
187
129
220
71
344
155
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
20
1 -0.68
11 -0.28
12 0.41
13 -0.29
14 0.42
15 0.34
17 0.28
18 0.66
2 -0.43
3 -0.68
30 0.15
33 0.4
4 -0.68
45 0.4
46 0.4
5 -0.57
6 -0.81
7 0.41
8 0.28
9 0.27
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
6.8
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
11
1 1 acceptor
1 1 donor
1 3 acceptor
1 3 donor
1 4 acceptor
1 4 donor
1 5 acceptor
1 6 cation
3 16 19 20 hydrophobe
5 6 7 11 12 13 rings
5 6 7 8 9 10 rings
21
4
1
3
0
0
0
0
1
1