3169
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
8
8
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
3
3
4
4
4
5
5
5
6
6
6
7
7
8
8
9
9
9
10
10
11
11
12
12
13
13
14
14
15
15
16
16
17
10
33
12
37
5
6
9
7
8
11
7
18
19
8
20
21
22
23
24
25
10
26
27
12
28
13
14
29
30
15
31
16
32
17
34
17
35
36
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
2
1
2
1
1
1
1
10
1
9
12
28
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
-5.2874
-5.1605
-1.698
1.1248
-1.1431
-0.7767
0.2068
0.5845
-3.0112
-4.0303
2.504
-4.2223
3.0184
3.4205
4.3933
4.7954
5.2818
-1.0246
-1.7865
-1.1866
-0.6437
0.6176
0.0607
0.4877
1.2522
-2.9536
-3.3947
-3.7752
-3.2917
-4.6163
2.3574
3.0646
-5.8829
4.7725
5.4873
6.3523
-6.0366
-0.6267
1.9408
-0.5879
-0.2259
0.1972
-1.6756
0.8103
-1.1244
-1.1234
-0.0143
0.0104
0.9335
1.3133
-1.048
1.5483
-0.8129
0.4852
-0.426
1.0401
-2.2607
-2.3613
1.3078
1.5705
-0.5741
-1.9732
-1.7882
-1.7457
0.5532
1.4361
0.4101
2.1649
-2.0669
0.0672
2.5587
-1.6402
0.6682
1.5228
-0.7134
0.4043
0.2168
-0.0289
-0.8925
0.5686
-0.5116
0.9991
-0.14
-0.4118
-0.0367
0.7701
0.1172
-0.1976
0.1106
-0.2042
-0.05
-1.7891
-1.1604
1.4008
-0.2792
-1.399
0.2666
1.944
1.1865
-1.013
0.68
-1.3123
1.0467
1.6477
0.2577
-0.3324
-1.0432
0.2335
-0.3321
-0.0551
0.3549
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
00000C6100000002
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
50.7628
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
40.605
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
11132069 177 17676203602118616463
11401426 45 18187642535158394807
11471102 20 18411418432236914590
117890 112 18344146990465566184
12107183 9 17623297073969494691
12236239 1 18341892991950209855
12596602 18 13695592156757189980
12644460 14 17603858954004823042
12916748 109 18410579504617131723
13167823 11 18201715188761709559
13544592 145 18336274466073749606
13675066 3 18041005063144972067
15048467 5 18342176661069938640
15196674 1 18410012147594579009
15209294 21 18408041793099262145
15375358 24 18410859888640721454
17349148 13 12391515290836831374
17834072 33 18130503119291738935
17959699 21 18342176682676741656
18186145 218 18259696809429053150
19489759 90 16271930393706937947
200 152 17846498145035382458
20300324 65 18060700606976333289
20645477 56 17822005445579441406
20645477 70 18272371945494644678
23402539 116 18202560666122021253
23402655 69 18341894121447474470
23536379 177 17989207031700509695
23559900 14 18334858346958216522
2916195 48 18412258471341091744
293599 30 18335985289908992417
34797466 226 17131277981397719780
351380 180 18272369775934571792
4047638 21 18260829315454539370
4214541 1 18342176674213075965
42788 4 18341894099476791766
495365 180 17988352789218788626
4990 188 18343304760110826246
5104073 3 18187643656672153184
542803 24 18343584053180535012
633830 44 18407755954240690998
69090 78 18409726296426417686
7495541 125 16486686000038258627
77779 3 18341613741312942806
8272917 22 18130231458716570822
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
328.15
12.15
1.62
0.83
3.39
0.2
-0.03
3.42
0.34
0.23
-0.26
0.37
-0.04
-0.3
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
670.013
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
190.1
Conformer
RMSD
7
2009.12.11
0.6
Diverse Conformer
ID List
6
2012.02.08
2
93
11
75
76
83
54
97
26
67
78
87
73
5
89
13
85
74
58
24
56
69
6
57
72
84
12
52
37
20
88
7
80
79
86
98
96
77
35
68
36
27
44
4
64
95
70
30
10
49
9
45
19
28
60
71
82
38
43
1
47
62
91
21
94
34
18
46
39
8
29
33
3
31
48
25
16
22
51
66
55
65
17
59
53
90
23
63
41
61
81
50
40
92
42
32
14
15
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
24
1 -0.68
10 0.28
11 0.1
12 0.28
13 -0.15
14 -0.15
15 -0.15
16 -0.15
17 -0.15
2 -0.68
3 -0.81
31 0.15
32 0.15
33 0.4
34 0.15
35 0.15
36 0.15
37 0.4
4 -0.84
5 0.27
6 0.27
7 0.37
8 0.37
9 0.27
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
5.2
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
8
1 1 acceptor
1 1 donor
1 2 acceptor
1 2 donor
1 3 cation
1 4 cation
6 11 13 14 15 16 17 rings
6 3 4 5 6 7 8 rings
17
1
0
1
0
0
0
0
1
1