31621
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
8
8
8
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
3
4
4
4
4
5
5
5
6
6
7
7
7
8
8
8
9
9
11
11
12
12
12
13
13
13
14
14
14
15
15
15
16
16
17
17
19
19
19
20
20
20
21
22
10
12
10
18
5
6
7
8
6
9
23
10
24
25
26
27
28
29
30
11
31
13
14
15
16
32
35
36
37
38
39
40
18
33
34
17
19
18
20
41
42
43
21
44
45
22
46
1
1
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
3
1
5
4
9
6
23
2
1
6
4
10
5
24
2
1
12
1
15
16
32
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
-0.3642
0.8011
-3.4612
2.4459
3.2141
1.978
3.0811
1.611
4.4881
0.7642
5.7111
-1.5944
6.9379
5.9649
-1.8272
-2.7306
-3.5371
-2.9941
-2.851
-4.7361
-5.9523
-6.9491
3.1606
2.0791
3.5169
3.8677
2.3358
0.6857
2.1552
1.345
4.4337
-1.6004
-2.1291
-0.9902
7.4435
6.7031
7.6356
5.0502
6.4374
6.6332
-2.9241
-3.7379
-1.9746
-4.6772
-4.7815
-7.8329
-0.7855
-0.2333
2.3127
0.4661
0.0423
-0.6859
0.2258
1.7027
-0.6481
-0.5358
-0.1012
-0.6772
-0.9609
1.3792
0.7601
-0.9798
0.0617
1.183
-2.3607
0.2122
-0.0727
-0.3049
0.6876
-1.6761
-0.7745
0.9628
0.3184
1.5685
2.5458
2.0033
-1.7357
-1.3699
0.8018
1.437
-0.7604
-2.03
-0.7491
1.9714
1.6559
1.6689
-3.0899
-2.4788
-2.6062
-0.4656
1.2233
-0.5109
-0.1054
-2.0222
-0.3988
0.847
-0.3703
0.0288
2.1753
0.8015
-0.2365
-0.8372
-0.0994
-0.8079
0.0281
-0.0608
-1.2579
0.1312
0.3777
-0.4148
0.687
1.2343
0.4641
-0.1639
-1.2422
0.464
2.2726
2.3698
2.9736
1.3722
1.2421
-0.2174
-0.2647
-1.6584
-2.3091
-1.071
0.9783
-0.0041
-0.7888
-0.1575
0.8874
-0.8784
-0.1261
1.3163
1.295
2.0935
1.6547
-0.7211
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
00007B8500000009
Energy
MMFF94 NoEstat
7
1.6.0
Szybki
openeye.com
2012.01.18
30.9366
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.01.18
30.446
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10 15 18187643643908933696
10354089 29 17489588956776696974
10366900 7 18335975454391933683
106641 1 17749394805550678337
10968037 39 8574709092355969771
11045977 3 18341050821904340803
11315181 36 17167870763704922389
11646440 116 14333413367241077827
12166972 35 16773792632108550865
12236239 1 17022626381292377855
12403259 415 17846205649056831905
12507557 5 17060338547724933154
12516196 113 15719391741500500887
12553582 1 16153980348056197922
12596602 18 17748826297941608080
12633257 1 18410005568089784409
12788726 201 9295021128702297087
14123256 10 13045945707591530282
14170010 4 15985109604573640862
14251764 18 17917990590296950732
14341114 176 18334580156945789044
15527383 91 17418092126881008088
15537594 2 16732978747511309770
15788980 27 12103844583810995548
1601671 61 17275386491569245276
17844677 252 18334863805613885964
1813 80 16009037129336356238
20281389 69 18343863316655582120
21033648 29 18130493163499856097
21065198 48 17023176068281443497
21267235 1 16226054378928634558
21521721 280 15357990005414643036
21792961 116 18272940384732358910
22224240 67 17676767651736731050
23402539 116 12823289092154500000
23536379 177 18260830376517189850
23559900 14 18337106886348320873
23569943 247 14475309655442730156
23622692 88 17676490561974370631
339767 52 16370727045638906265
34797466 226 18339092553172487236
3545911 37 17632859724264919479
5486654 2 13840270282180873512
57724786 102 17346027982918019872
59755656 215 18408325458177432583
59755656 520 16415473853206234191
9996256 80 18060698394741303847
Shape
Multipoles
8
1.8.1
OEShape
openeye.com
2012.01.18
435.14
16.1
1.58
1.3
3.13
0.16
0.17
-0.4
1.77
-0.58
0.11
0.22
0.09
0.63
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.01.18
900.179
Shape
Volume
7
1.8.1
OEShape
openeye.com
2012.01.18
253
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.02.08
9
130
122
168
118
81
141
31
87
172
32
154
173
54
82
85
117
176
175
62
163
161
29
162
167
110
158
129
127
103
183
101
108
180
121
24
23
88
137
170
159
124
116
133
152
2
22
126
182
166
55
40
64
84
106
113
179
76
184
53
169
46
115
38
149
128
155
95
99
145
19
140
151
148
131
147
78
89
91
178
157
143
37
86
144
107
138
156
10
136
146
164
96
92
100
39
58
160
109
30
112
49
150
7
74
120
177
94
65
125
123
60
20
174
111
43
135
80
61
72
1
33
18
27
44
171
93
77
119
51
56
132
41
52
90
36
105
6
181
11
97
50
153
66
17
114
102
25
45
98
28
79
16
69
21
34
73
35
75
165
15
5
134
26
14
8
139
71
83
142
12
59
3
13
68
42
48
4
57
63
104
67
70
47
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
26
1 -0.43
10 0.72
11 -0.28
12 0.42
13 0.14
14 0.14
15 0.06
16 -0.28
17 -0.12
18 0.49
19 0.14
2 -0.57
20 0.34
21 -0.2
22 -0.18
23 0.1
24 0.1
3 -0.57
31 0.15
4 -0.19
46 0.18
5 -0.06
6 -0.1
7 0.09
8 0.09
9 -0.19
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
6
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
6
1 2 acceptor
1 22 hydrophobe
1 3 acceptor
3 11 13 14 hydrophobe
3 4 7 8 hydrophobe
5 12 15 16 17 18 rings
22
3
2
1
0
0
0
0
1
5