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Compound Summary for: CID 3117

Disulfiram

Also known as: Tetraethylthiuram disulfide, Antabuse, Alcophobin, Antabus, Anticol, Esperal, Teturam, Dicupral, Refusal
Molecular Formula: C10H20N2S4   Molecular Weight: 296.5392   InChIKey: AUZONCFQVSMFAP-UHFFFAOYSA-N
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.   From: MeSH
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